List of Predicted Activities

No - number of activity
Active compounds - number of active compounds
IAP - Invariant accuracy of prediction

This is Activities List for PASS Online

No Activity Type Active compounds IAP
1 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase inhibitor64,445
2 (R)-3-amino-2-methylpropionate-pyruvate transaminase inhibitor240,31
3 (R)-6-hydroxynicotine oxidase inhibitor37,039
4 (R)-aminopropanol dehydrogenase inhibitor100,94
5 (R)-limonene 6-monooxygenase inhibitor30,311
6 (R)-Pantolactone dehydrogenase (flavin) inhibitor812,764
7 (R,R)-butanediol dehydrogenase inhibitor30,535
8 (S)-2-hydroxy-acid oxidase inhibitor287,424
9 (S)-2-Methylmalate dehydratase inhibitor40,348
10 (S)-3-amino-2-methylpropionate transaminase inhibitor84,569
11 (S)-3-hydroxyacid ester dehydrogenase inhibitor30,917
12 (S)-6-hydroxynicotine oxidase inhibitor44,741
13 (S)-carnitine 3-dehydrogenase inhibitor71,228
14 (S)-methylmalonyl-CoA hydrolase inhibitor80,002
15 [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] kinase inhibitor340,811
16 [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase inhibitor120,02
17 [acetyl-CoA carboxylase] kinase inhibitor60,451
18 [acyl-carrier-protein] S-acetyltransferase inhibitor74,377
19 [acyl-carrier-protein] S-malonyltransferase inhibitor101,265
20 [citrate-(pro-3S)-lyase] thiolesterase inhibitor40,082
21 [glutamate-ammonia-ligase] adenylyltransferase inhibitor130,29
22 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase inhibitor114,446
23 [hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase inhibitor80,186
24 [Isocitrate dehydrogenase (NADP+)] kinase inhibitor90,21
25 [myelin basic protein]-arginine N-methyltransferase inhibitor31,589
26 [phosphorylase] phosphatase inhibitor145,51
27 [protein-PII] uridylyltransferase inhibitor270,271
28 [Skp1-protein]-hydroxyproline N-acetylglucosaminyltransferase inhibitor50,263
29 1,2-alpha-L-fucosidase inhibitor55,174
30 1,3-Beta-glucan synthase inhibitor30,078
31 1,4-Alpha-glucan branching enzyme inhibitor44,079
32 1,4-Lactonase inhibitor419,195
33 1,5-Anhydro-D-fructose reductase inhibitor90,745
34 11-Beta-hydroxysteroid dehydrogenase 1 inhibitor17370,794
35 11-Beta-hydroxysteroid dehydrogenase 2 inhibitor2530,234
36 11-Beta-hydroxysteroid dehydrogenase inhibitor17890,828
37 11-Cis-retinyl-palmitate hydrolase inhibitor40,398
38 12-Lipoxygenase inhibitor862,316
39 15-Hydroxyprostaglandin-D dehydrogenase (NADP+) inhibitor83,142
40 15-Lipoxygenase inhibitor2691,735
41 17-Beta-hydroxysteroid dehydrogenase 1 inhibitor491,837
42 17-Beta-hydroxysteroid dehydrogenase 5 inhibitor60,001
43 1-Acylglycerol-3-phosphate O-acyltransferase inhibitor4511,79
44 1-Alkyl-2-acetylglycerol O-acyltransferase inhibitor30,21
45 1-Alkyl-2-acetylglycerophosphocholine esterase inhibitor4410,74
46 1-Alkylglycerophosphocholine O-acetyltransferase inhibitor247,386
47 1-Aminocyclopropane-1-carboxylate deaminase inhibitor111,245
48 1-Deoxy-D-xylulose-5-phosphate reductoisomerase inhibitor120,178
49 1-Phosphofructokinase inhibitor90,948
50 1-Pyrroline-5-carboxylate dehydrogenase inhibitor241,048
51 2-(acetamidomethylene)succinate hydrolase inhibitor110,09
52 2,2-Dialkylglycine decarboxylase (pyruvate) inhibitor71,121
53 2,3,4,5-Tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase inhibitor52,85
54 2,3-Dihydroxyindole 2,3-dioxygenase inhibitor41,476
55 2,3-Oxidosqualene-lanosterol cyclase inhibitor1421,18
56 2,4-Diaminopentanoate dehydrogenase inhibitor31,035
57 2,4-Dichlorophenol 6-monooxygenase inhibitor92,859
58 2,5-Dihydroxypyridine 5,6-dioxygenase inhibitor71,039
59 2,6-Dihydroxypyridine 3-monooxygenase inhibitor31,709
60 27-Hydroxycholesterol 7alpha-monooxygenase inhibitor617,114
61 2-Acylglycerol O-acyltransferase inhibitor186,119
62 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase inhibitor40,128
63 2-Aminoadipate transaminase inhibitor61,498
64 2-Aminoethylphosphonate-pyruvate transaminase inhibitor90,936
65 2-Aminohexano-6-lactam racemase inhibitor191,533
66 2-Aminohexanoate transaminase inhibitor30,004
67 2-Dehydro-3-deoxy-L-arabinonate dehydratase inhibitor40,64
68 2-Dehydro-3-deoxy-phosphogluconate aldolase inhibitor60,839
69 2-Dehydropantoate 2-reductase inhibitor718,938
70 2-Dehydropantoate aldolase inhibitor30,819
71 2-Dehydropantolactone reductase (A-specific) inhibitor100,914
72 2-Enoate reductase inhibitor103,82
73 2-Ethylmalate synthase inhibitor30,044
74 2-Haloacid dehalogenase (configuration-inverting) inhibitor61,425
75 2-Haloacid dehalogenase inhibitor32,653
76 2-Hydroxy-3-oxoadipate synthase inhibitor31,731
77 2-Hydroxy-3-oxopropionate reductase inhibitor50,957
78 2-Hydroxyacylsphingosine 1-beta-galactosyltransferase inhibitor30,003
79 2-Hydroxymuconate-semialdehyde hydrolase inhibitor76,686
80 2-Hydroxyquinoline 8-monooxygenase inhibitor615,855
81 2-Isopropylmalate synthase inhibitor150,161
82 2-Methylacyl-CoA dehydrogenase inhibitor71,496
83 2-Methyl-branched-chain-enoyl-CoA reductase inhibitor52,012
84 2-Methylcitrate dehydratase inhibitor40,368
85 2-Methylcitrate synthase inhibitor32,19
86 2-Methyleneglutarate mutase inhibitor90,842
87 2-Nitrophenol 2-monooxygenase inhibitor30,959
88 2-Nitropropane dioxygenase inhibitor213,236
89 2-Oxoaldehyde dehydrogenase (NAD+) inhibitor120,904
90 2-Oxoaldehyde dehydrogenase (NADP+) inhibitor31,495
91 2-Oxoglutarate decarboxylase inhibitor81,76
92 2-Oxoisovalerate dehydrogenase (acylating) inhibitor40,767
93 2-Pyrocatechuate decarboxylase inhibitor200,811
94 3 Beta-hydroxy-delta 5-steroid dehydrogenase inhibitor970,026
95 3'(2'),5'-Bisphosphate nucleotidase inhibitor40,335
96 3(or 17)alpha-hydroxysteroid dehydrogenase inhibitor90,725
97 3(or 17)beta-hydroxysteroid dehydrogenase inhibitor632,283
98 3,4-Dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase inhibitor41,433
99 3,4-Dihydroxyphenylacetate 2,3-dioxygenase inhibitor120,397
100 3-Alpha-hydroxysteroid dehydrogenase (B-specific) inhibitor72,664
101 3-Aminobutyryl-CoA ammonia-lyase inhibitor30,638
102 3-Carboxyethylcatechol 2,3-dioxygenase inhibitor41,114
103 3-Chloro-D-alanine dehydrochlorinase inhibitor41,221
104 3C-like protease (Human coronavirus) inhibitor2911,088
105 3-Cyanoalanine hydratase inhibitor416,136
106 3-Dehydroquinate dehydratase inhibitor140,595
107 3-Dehydroquinate synthase inhibitor160,517
108 3'-Demethylstaurosporine O-methyltransferase inhibitor43,06
109 3-Demethylubiquinone-9 3-O-methyltransferase inhibitor31,39
110 3-Deoxy-7-phosphoheptulonate synthase inhibitor480,827
111 3-Deoxy-8-phosphooctulonate synthase inhibitor80,519
112 3-Galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase inhibitor30,641
113 3-Hydroxy-4-oxoquinoline 2,4-dioxygenase inhibitor61,923
114 3-Hydroxyacyl-CoA dehydrogenase inhibitor60,924
115 3-Hydroxyanthranilate 3,4-dioxygenase inhibitor145,436
116 3-Hydroxyanthranilate oxidase inhibitor131,962
117 3-Hydroxybenzoate 4-monooxygenase inhibitor71,914
118 3-Hydroxybenzoate 6-monooxygenase inhibitor515,728
119 3-Hydroxybutyrate dehydrogenase inhibitor251,002
120 3-Hydroxybutyryl-CoA dehydrogenase inhibitor31,035
121 3-Hydroxydecanoyl-[acyl-carrier-protein] dehydratase inhibitor91,053
122 3-Hydroxyisobutyryl-CoA hydrolase inhibitor70,003
123 3-Hydroxyphenylacetate 6-hydroxylase inhibitor40,944
124 3-Isopropylmalate dehydratase inhibitor81,38
125 3-Isopropylmalate dehydrogenase inhibitor70,44
126 3-Ketovalidoxylamine C-N-lyase inhibitor41,515
127 3-Mercaptopyruvate sulfurtransferase inhibitor90,026
128 3-Methyl-2-oxobutanoate dehydrogenase (lipoamide) inhibitor150,467
129 3-Methyl-2-oxobutanoate hydroxymethyltransferase inhibitor81,842
130 3-Methylbutanal reductase inhibitor914,246
131 3'-Nucleotidase inhibitor82,195
132 3-Oxoacid CoA-transferase inhibitor260,666
133 3-Oxoacyl-[acyl-carrier-protein] synthase II inhibitor91,618
134 3-Oxoacyl-[acyl-carrier-protein] synthase III inhibitor321,941
135 3-Oxoacyl-[acyl-carrier-protein] synthase inhibitor541,646
136 3-Oxoadipate enol-lactonase inhibitor30,724
137 3-Oxosteroid 1-dehydrogenase inhibitor60,556
138 3-Phosphoshikimate 1-carboxyvinyltransferase inhibitor410,288
139 3-Phytase inhibitor911,177
140 4,5-Dihydroxyphthalate decarboxylase inhibitor166,958
141 4a-Hydroxytetrahydrobiopterin dehydratase inhibitor30,172
142 4-Alpha-glucanotransferase inhibitor80,854
143 4-Carboxymethyl-4-methylbutenolide mutase inhibitor90,536
144 4-Chlorobenzoyl-CoA dehalogenase inhibitor72,294
145 4-Chlorophenylacetate 3,4-dioxygenase inhibitor41,236
146 4-Coumarate-CoA ligase inhibitor814,796
147 4-Hydroxy-2-oxoglutarate aldolase inhibitor170,537
148 4-Hydroxy-4-methyl-2-oxoglutarate aldolase inhibitor110,462
149 4-Hydroxybenzoate 1-hydroxylase inhibitor30,047
150 4-Hydroxybenzoate 3-monooxygenase [NAD(P)H] inhibitor60,022
151 4-Hydroxybenzoate 3-monooxygenase inhibitor281,415
152 4-Hydroxybenzoate decarboxylase inhibitor70,266
153 4-Hydroxybenzoate nonaprenyltransferase inhibitor153,388
154 4-Hydroxybenzoate-CoA ligase inhibitor40,199
155 4-Hydroxyglutamate transaminase inhibitor41,426
156 4-Hydroxymandelate oxidase inhibitor107,342
157 4-Hydroxyphenylacetate 1-monooxygenase inhibitor40,015
158 4-Hydroxyphenylacetate 3-monooxygenase inhibitor812,11
159 4-Hydroxyphenylpyruvate dioxygenase inhibitor220,497
160 4-Hydroxyproline epimerase inhibitor812,455
161 4-Methoxybenzoate monooxygenase (O-demethylating) inhibitor1910,785
162 4-Nitrophenol 2-monooxygenase inhibitor617,991
163 4-Nitrophenylphosphatase inhibitor4710,387
164 4-Phytase inhibitor131,437
165 4-Pyridoxolactonase inhibitor60,59
166 5 Hydroxytryptamine 1 agonist19031,35
167 5 Hydroxytryptamine 1 antagonist47871,792
168 5 Hydroxytryptamine 1A agonist11311,162
169 5 Hydroxytryptamine 1A antagonist38531,489
170 5 Hydroxytryptamine 1B agonist651,026
171 5 Hydroxytryptamine 1B antagonist10271,398
172 5 Hydroxytryptamine 1D agonist6950,447
173 5 Hydroxytryptamine 1D antagonist10721,469
174 5 Hydroxytryptamine 1E antagonist338,922
175 5 Hydroxytryptamine 1F agonist1150,072
176 5 Hydroxytryptamine 1F antagonist2161,005
177 5 Hydroxytryptamine 2 agonist4790,882
178 5 Hydroxytryptamine 2 antagonist42272,624
179 5 Hydroxytryptamine 2A agonist594,988
180 5 Hydroxytryptamine 2A antagonist29611,912
181 5 Hydroxytryptamine 2B agonist95,307
182 5 Hydroxytryptamine 2B antagonist8612,182
183 5 Hydroxytryptamine 2C agonist4150,487
184 5 Hydroxytryptamine 2C antagonist17811,532
185 5 Hydroxytryptamine 3 agonist733,09
186 5 Hydroxytryptamine 3 antagonist16791,123
187 5 Hydroxytryptamine 3A antagonist2542,293
188 5 Hydroxytryptamine 4 agonist3430,548
189 5 Hydroxytryptamine 4 antagonist5710,545
190 5 Hydroxytryptamine 4A antagonist76,475
191 5 Hydroxytryptamine 4B antagonist60,058
192 5 Hydroxytryptamine 4C antagonist42,233
193 5 Hydroxytryptamine 4D antagonist42,233
194 5 Hydroxytryptamine 4E antagonist270,49
195 5 Hydroxytryptamine 5 antagonist1261,644
196 5 Hydroxytryptamine 5A antagonist1241,491
197 5 Hydroxytryptamine 6 agonist290,808
198 5 Hydroxytryptamine 6 antagonist7640,864
199 5 Hydroxytryptamine 7 agonist87,395
200 5 Hydroxytryptamine 7 antagonist5601,619
201 5 Hydroxytryptamine 7L antagonist54,871
202 5 Hydroxytryptamine 7S antagonist55,384
203 5 Hydroxytryptamine agonist29062,141
204 5 Hydroxytryptamine antagonist108563,381
205 5 Hydroxytryptamine release inhibitor3312,9
206 5 Hydroxytryptamine release stimulant178,829
207 5 Hydroxytryptamine uptake inhibitor43111,479
208 5 Hydroxytryptamine uptake stimulant518,651
209 5 Lipoxygenase activating protein inhibitor1440,039
210 5-Alpha-reductase 1 inhibitor4670,374
211 5-Alpha-reductase 2 inhibitor5090,657
212 5-Alpha-reductase inhibitor14630,592
213 5-Aminolevulinate synthase inhibitor252,119
214 5-Aminovalerate transaminase inhibitor70,352
215 5-Formyltetrahydrofolate cyclo-ligase inhibitor117,033
216 5-Guanidino-2-oxopentanoate decarboxylase inhibitor80,009
217 5-Hydroxypentanoate CoA-transferase inhibitor40,016
218 5-Lipoxygenase inhibitor19981,681
219 5-Methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase inhibitor40,412
220 5'-Nucleotidase inhibitor450,558
221 5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase inhibitor311,784
222 5-Oxoprolinase (ATP-hydrolysing) inhibitor80,421
223 6,7-Dihydropteridine reductase inhibitor472,543
224 6-Carboxyhexanoate-CoA ligase inhibitor31,059
225 6-Methylsalicylate decarboxylase inhibitor81,087
226 6-Phospho-beta-glucosidase inhibitor80,21
227 6-Phosphofructo-2-kinase inhibitor110,655
228 6-Pyruvoyltetrahydropterin synthase inhibitor41,268
229 8-Amino-7-oxononanoate synthase inhibitor152,41
230 8-oxodGTPase stimulant120,017
231 ABCA1 expression enhancer2112,234
232 Abl kinase inhibitor6042,918
233 Abortion inducer385,074
234 Acaricide425,527
235 Acetate kinase inhibitor119,204
236 Acetate-CoA ligase inhibitor231,311
237 Acetoacetate decarboxylase inhibitor80,758
238 Acetoacetyl-CoA reductase inhibitor100,204
239 Acetoin dehydrogenase inhibitor151,422
240 Acetolactate decarboxylase inhibitor151,717
241 Acetolactate synthase inhibitor201,596
242 Acetylcholine agonist20532,613
243 Acetylcholine antagonist39402,746
244 Acetylcholine M1 receptor agonist10140,776
245 Acetylcholine M1 receptor antagonist12631,218
246 Acetylcholine M2 receptor agonist392,902
247 Acetylcholine M2 receptor antagonist13741,127
248 Acetylcholine M3 receptor agonist160,37
249 Acetylcholine M3 receptor antagonist13971,366
250 Acetylcholine M4 receptor agonist570,506
251 Acetylcholine M4 receptor antagonist7061,145
252 Acetylcholine M5 receptor antagonist5911,047
253 Acetylcholine muscarinic agonist12161,167
254 Acetylcholine muscarinic antagonist30512,136
255 Acetylcholine neuromuscular blocking agent1817,252
256 Acetylcholine nicotinic agonist8022,163
257 Acetylcholine nicotinic antagonist9472,112
258 Acetylcholine release stimulant1463,749
259 Acetylcholinesterase stimulant60,012
260 Acetyl-CoA C-acyltransferase inhibitor103,589
261 Acetyl-CoA carboxylase 1 inhibitor960,798
262 Acetyl-CoA carboxylase 2 inhibitor2600,004
263 Acetyl-CoA carboxylase inhibitor2790,818
264 Acetyl-CoA transferase 1 inhibitor6021,029
265 Acetyl-CoA transferase 2 inhibitor2262,03
266 Acetyl-CoA transferase inhibitor15691,121
267 Acetylenecarboxylate hydratase inhibitor31,109
268 Acetylesterase inhibitor613,366
269 Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase inhibitor617,321
270 Acetylornithine deacetylase inhibitor41,506
271 Acetylserotonin O-methyltransferase inhibitor118,852
272 Acetylspermidine deacetylase inhibitor164,881
273 Acid phosphatase 1 inhibitor50,001
274 Acid phosphatase inhibitor434,491
275 Acidifying agent gastric60,188
276 Acidifying agent non gastric74,479
277 Acidosis13018,786
278 Acidosis, lactic911,607
279 Acidosis, metabolic4515,39
280 Acid-sensing ion channel blocker611,757
281 ACK1 kinase inhibitor96,672
282 Acneiform eruption35,323
283 Aconitate decarboxylase inhibitor40,397
284 Aconitate hydratase inhibitor220,813
285 Acrocylindropepsin inhibitor312,297
286 Acrosin inhibitor203,493
287 Actin depolymerization stimulant80,156
288 Actin polymerization inhibitor50,004
289 Activin receptor-like kinase 4 inhibitor230,021
290 Acute neurologic disorders treatment118318,967
291 Acylaminoacyl-peptidase inhibitor253,675
292 Acylcarnitine hydrolase inhibitor38,131
293 Acyl-CoA dehydrogenase (NADP+) inhibitor191,05
294 Acyl-CoA dehydrogenase inhibitor150,649
295 Acyl-CoA hydrolase inhibitor442,13
296 Acyl-CoA oxidase inhibitor118,573
297 Acylglycerone-phosphate reductase inhibitor61,429
298 Acyl-lysine deacylase inhibitor30,577
299 Acyloxyacyl hydrolase inhibitor151,378
300 Acylphosphatase inhibitor132,094
301 ADAM inhibitor540,301
302 ADAM10 endopeptidase inhibitor1251,335
303 Adamalysin inhibitor80,329
304 Adenine deaminase inhibitor101,235
305 Adenine nucleotide translocase inhibitor233,679
306 Adenine nucleotide translocator 1 inhibitor30
307 Adenine phosphoribosyltransferase inhibitor230,521
308 Adenomatous polyposis treatment105,918
309 Adenosine A1 receptor agonist2730,096
310 Adenosine A1 receptor agonist enhancer100,001
311 Adenosine A1 receptor antagonist26231,118
312 Adenosine A2 receptor agonist2390,114
313 Adenosine A2 receptor antagonist28191,044
314 Adenosine A2a receptor agonist2160,088
315 Adenosine A2a receptor antagonist20911,032
316 Adenosine A2b receptor agonist170,112
317 Adenosine A2b receptor antagonist8520,695
318 Adenosine A3 receptor agonist880,198
319 Adenosine A3 receptor antagonist13651,971
320 Adenosine deaminase inhibitor1651,615
321 Adenosine kinase inhibitor3340,41
322 Adenosine receptor agonist6140,528
323 Adenosine receptor antagonist43101,725
324 Adenosine regulator39,856
325 Adenosine uptake inhibitor550,05
326 Adenosylhomocysteine nucleosidase inhibitor570,011
327 Adenosylmethionine cyclotransferase inhibitor120,041
328 Adenosylmethionine-8-amino-7-oxononanoate transaminase inhibitor121,354
329 Adenylate cyclase I inhibitor540,306
330 Adenylate cyclase I stimulant430
331 Adenylate cyclase inhibitor1745,028
332 Adenylate cyclase stimulant896,284
333 Adenylate cyclase V inhibitor364,016
334 Adenylate kinase inhibitor236,452
335 Adenylosuccinate lyase inhibitor290,391
336 Adenylosuccinate synthase inhibitor600,844
337 Adenylyl-sulfate kinase inhibitor202,771
338 Adenylyl-sulfate reductase inhibitor510,117
339 Adenylylsulphatase inhibitor171,917
340 ADP-ribose diphosphatase inhibitor70,218
341 ADP-ribosylarginine hydrolase inhibitor67,59
342 ADP-thymidine kinase inhibitor54,77
343 Adrenal cortex hypoplasia37,509
344 Adrenaline agonist20552,131
345 Adrenaline antagonist64302,818
346 Adrenaline release stimulant86,619
347 Adrenaline uptake inhibitor23661,216
348 Adrenergic45092,373
349 Adrenergic, ophthalmic90,83
350 Aerobactin synthase inhibitor30,877
351 Agaritine gamma-glutamyltransferase inhibitor110,97
352 Age-related macular degeneration treatment5111,901
353 Aggrecanase 1 inhibitor482,32
354 Aggrecanase 2 inhibitor1170,595
355 Aggrecanase inhibitor3100,518
356 Agmatinase inhibitor77,567
357 Agranulocytosis40815,924
358 AgrC-1 protein inhibitor40
359 AgrC-2 protein inhibitor40
360 AICAR transformylase inhibitor393,823
361 Akathisia8415,369
362 Alanine carboxypeptidase inhibitor100,59
363 Alanine dehydrogenase inhibitor271,076
364 Alanine racemase inhibitor121,57
365 Alanine transaminase inhibitor181,377
366 Alanine-tRNA ligase inhibitor63,016
367 Albendazole monooxygenase inhibitor33,017
368 Alcohol dehydrogenase (acceptor) inhibitor1112,794
369 Alcohol dehydrogenase (NADP+) inhibitor454,135
370 Alcohol dehydrogenase [NAD(P)+] inhibitor167,207
371 Alcohol dehydrogenase alpha inhibitor120,002
372 Alcohol dehydrogenase beta 1 inhibitor70,001
373 Alcohol dehydrogenase beta inhibitor70,001
374 Alcohol dehydrogenase gamma 2 inhibitor60,007
375 Alcohol dehydrogenase gamma inhibitor60,007
376 Alcohol dehydrogenase I inhibitor140,001
377 Alcohol dehydrogenase inhibitor1194,311
378 Alcohol dehydrogenase substrate714,534
379 Alcohol O-acetyltransferase inhibitor99,209
380 Alcohol oxidase inhibitor171,123
381 Aldehyde dehydrogenase (NAD+) inhibitor383,98
382 Aldehyde dehydrogenase (NADP+) inhibitor173,323
383 Aldehyde dehydrogenase (pyrroloquinoline-quinone) inhibitor712,336
384 Aldehyde dehydrogenase [NAD(P)+] inhibitor50,764
385 Aldehyde dehydrogenase 1 substrate80,112
386 Aldehyde dehydrogenase 1A2 inhibitor300,537
387 Aldehyde dehydrogenase 2 substrate614,501
388 Aldehyde dehydrogenase 3 substrate50,127
389 Aldehyde dehydrogenase inhibitor1144,001
390 Aldehyde dehydrogenase substrate554,055
391 Aldehyde ferredoxin oxidoreductase inhibitor51,14
392 Aldehyde oxidase inhibitor2710,971
393 Aldehyde oxidase substrate515,777
394 Aldose 1-epimerase inhibitor310,68
395 Aldose reductase 2 inhibitor880,439
396 Aldose reductase inhibitor8031,39
397 Aldose reductase substrate113,637
398 Aldosterone antagonist5812,837
399 ALK inhibitor1213,638
400 Alkaline phosphatase inhibitor3364,313
401 Alkanal monooxygenase (FMN-linked) inhibitor274,17
402 Alkane 1-monooxygenase inhibitor44,92
403 Alkene monooxygenase inhibitor30,925
404 Alkenylglycerophosphocholine hydrolase inhibitor58,908
405 Alkenylglycerophosphoethanolamine hydrolase inhibitor66,941
406 Alkylacetylglycerophosphatase inhibitor411,842
407 Alkylator5625,295
408 Alkylglycerone-phosphate synthase inhibitor61,956
409 Alkylglycerophosphoethanolamine phosphodiesterase inhibitor52,744
410 Allantoate deiminase inhibitor30,692
411 Allantoicase inhibitor91,03
412 Allantoin racemase inhibitor40,975
413 Allantoinase inhibitor40,73
414 Allergic contact dermatitis9315,511
415 Allergic dermatitis7314,688
416 Allergic rhinitis treatment4093,568
417 Allophanate hydrolase inhibitor51,362
418 All-trans-retinyl-palmitate hydrolase inhibitor45,498
419 Allyl-alcohol dehydrogenase inhibitor61,728
420 Alopecia treatment613,534
421 Alpha 1 adrenoreceptor agonist780,776
422 Alpha 1 adrenoreceptor antagonist38762,191
423 Alpha 1a adrenoreceptor agonist480,032
424 Alpha 1a adrenoreceptor antagonist31421,764
425 Alpha 1b adrenoreceptor antagonist13311,684
426 Alpha 1d adrenoreceptor antagonist15121,464
427 Alpha 1L adrenoreceptor agonist30,673
428 Alpha 1L adrenoreceptor antagonist112,775
429 Alpha 2 adrenoreceptor agonist3371,291
430 Alpha 2 adrenoreceptor antagonist16081,98
431 Alpha 2a adrenoreceptor antagonist6291,912
432 Alpha 2b adrenoreceptor agonist450,085
433 Alpha 2b adrenoreceptor antagonist4202,507
434 Alpha 2c adrenoreceptor agonist450,04
435 Alpha 2c adrenoreceptor antagonist4972,217
436 Alpha 2d adrenoreceptor agonist440,155
437 Alpha 2d adrenoreceptor antagonist941,19
438 Alpha 3 adrenoreceptor agonist50,649
439 Alpha adrenoreceptor agonist4962,02
440 Alpha adrenoreceptor antagonist51262,909
441 Alpha galactosidase inhibitor160,038
442 Alpha glucosidase I inhibitor50,009
443 Alpha glucosidase II inhibitor80,004
444 Alpha glucosidase inhibitor1152,026
445 Alpha,alpha-phosphotrehalase inhibitor50,688
446 Alpha,alpha-trehalase inhibitor201,42
447 Alpha,alpha-trehalose phosphorylase (configuration-retaining) inhibitor110,541
448 Alpha,alpha-trehalose phosphorylase inhibitor40,141
449 Alpha,alpha-trehalose-phosphate synthase (UDP-forming) inhibitor143,099
450 Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase inhibitor110,152
451 Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase inhibitor30,364
452 Alpha-1,6-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase inhibitor44,012
453 Alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase inhibitor50,871
454 Alpha-amino-acid esterase inhibitor40,089
455 Alpha-amylase inhibitor285,137
456 Alpha-glucuronidase inhibitor42,12
457 Alpha-L-fucosidase inhibitor440,942
458 Alpha-L-rhamnosidase inhibitor110,632
459 Alpha-mannosidase inhibitor591,484
460 Alpha-Methylacyl-CoA racemase inhibitor81,893
461 Alpha-N-acetylgalactosaminidase inhibitor30,532
462 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase inhibitor170,427
463 Alpha-N-acetylglucosaminidase inhibitor42,032
464 Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase inhibitor150,266
465 Alpha-N-arabinofuranosidase inhibitor91,685
466 Alpha-pinene-oxide decyclase inhibitor81,207
467 Alternansucrase inhibitor40,236
468 Altronate dehydratase inhibitor70,111
469 Alzheimer's disease treatment249310,821
470 Amidase inhibitor1242,631
471 Amidophosphoribosyltransferase inhibitor250,268
472 Amiloride-sensitive cation channel 3 blocker70
473 Amine dehydrogenase inhibitor1012,64
474 Amino acid-polyamine-organocation (APC) transporter antagonist820,019
475 Amino-acid N-acetyltransferase inhibitor250,682
476 Amino-acid racemase inhibitor60,391
477 Aminoacylase inhibitor191,728
478 Aminoacyl-tRNA hydrolase inhibitor50,556
479 Aminoacyl-tRNA synthetase inhibitor3212,517
480 Aminobutyraldehyde dehydrogenase inhibitor313,088
481 Aminocarboxymuconate-semialdehyde decarboxylase inhibitor61,153
482 Aminoglycoside N6'-acetyltransferase inhibitor150,032
483 Aminolevulinate transaminase inhibitor260,913
484 Aminomuconate-semialdehyde dehydrogenase inhibitor42,05
485 Aminopeptidase A inhibitor550,094
486 Aminopeptidase B inhibitor456,05
487 Aminopeptidase I inhibitor261,619
488 Aminopeptidase microsomal inhibitor2092,127
489 Aminopeptidase N inhibitor1831,804
490 Aminopeptidase P inhibitor90,002
491 Aminopeptidase Y inhibitor82,218
492 AMP deaminase 2 inhibitor690,004
493 AMP deaminase 3 inhibitor210,223
494 AMP deaminase inhibitor1031,369
495 AMP nucleosidase inhibitor150,485
496 AMPA 1 receptor antagonist6810,459
497 AMPA 2 receptor antagonist4520,78
498 AMPA 3 receptor antagonist4370,753
499 AMPA 4 receptor antagonist2221,116
500 AMPA 5 receptor antagonist40
501 AMPA receptor agonist720,612
502 AMPA receptor antagonist13170,948
503 Amylin agonist100
504 Amylo-alpha-1,6-glucosidase inhibitor260,703
505 Amyloid beta aggregation inhibitor392,526
506 Amyloid beta precursor protein antagonist2955,291
507 Amylosucrase inhibitor50,102
508 Amyotrophic lateral sclerosis treatment1809,625
509 Anabolic1583,969
510 Analeptic23410,879
511 Analgesic841813,497
512 Analgesic stimulant2213,226
513 Analgesic, non-opioid621011,735
514 Anaphylatoxin receptor antagonist510,318
515 Androgen agonist2191,463
516 Androgen antagonist12801,791
517 Andropause treatment852,679
518 Androst-4-ene-3,17-dione monooxygenase inhibitor90,695
519 Anemia22815,192
520 Anemia, sideroblastic42,623
521 Anesthetic7075,868
522 Anesthetic general1518,835
523 Anesthetic inhalation201,216
524 Anesthetic local4633,89
525 Angiogenesis inhibitor44899,161
526 Angiogenesis stimulant2313,636
527 Angiotensin agonist120,913
528 Angiotensin antagonist34331,056
529 Angiotensin AT1 receptor antagonist30181,027
530 Angiotensin AT1A receptor antagonist9730,228
531 Angiotensin AT2 receptor agonist71,255
532 Angiotensin AT2 receptor antagonist10390,291
533 Angiotensin II receptor agonist97,409
534 Angiotensin II receptor antagonist34071,003
535 Angiotensin-converting enzyme inhibitor6941,605
536 Anhydrotetracycline monooxygenase inhibitor40,411
537 Anorexiant36317,19
538 Anthranilate 3-monooxygenase (deaminating) inhibitor114,163
539 Anthranilate phosphoribosyltransferase inhibitor50,341
540 Anthranilate synthase inhibitor231,523
541 Anthranilate-CoA ligase inhibitor41,801
542 Anthrax lethal factor inhibitor616,527
543 Antiacne12023,03
544 Antiacromegalic712,371
545 Antiadrenergic65012,983
546 Antialcoholic1218,976
547 Antiallergic619511,824
548 Antiamyloidogenic26910,384
549 Antianemic1825,229
550 Antianginal85017,012
551 Antianorexic636,842
552 Antiarrhythmic22016,532
553 Antiarthritic945313,525
554 Antiasthmatic760911,229
555 Antibacterial69508,08
556 Antibacterial, ophthalmic118,542
557 Antibiotic34813,185
558 Antibiotic Aminoglycoside-like483,154
559 Antibiotic Anthracycline-like73,781
560 Antibiotic beta Lactam-like7680,488
561 Antibiotic Carbacephem-like220,017
562 Antibiotic Carbapenem-like1530,129
563 Antibiotic Cephalosporin-like3480,036
564 Antibiotic Glycopeptide-like321,91
565 Antibiotic Isocephem-like70,002
566 Antibiotic Macrolide-like5840,178
567 Antibiotic Naphthyridine-like300,025
568 Antibiotic Oxacephem-like120,078
569 Antibiotic Oxazolidinone-like901,001
570 Antibiotic Penem-like410,006
571 Antibiotic Penicillin-like500,015
572 Antibiotic Quinolone-like3050,818
573 Antibiotic Rifamycin-like640,004
574 Antibiotic Tetracycline-like121,927
575 Antibiotic Tribactam-like170,001
576 Antibiotic Trimethoprim-like100,024
577 Anticarcinogenic3689,196
578 Anticataract635,031
579 Anticholelithogenic412,162
580 Anticoagulant23975,113
581 Anticonvulsant146611,676
582 Antidepressant80068,069
583 Antidepressant, Imipramin-like874,262
584 Antidiabetic1153010,712
585 Antidiabetic (type 1)1026,85
586 Antidiabetic (type 2)28355,847
587 Antidiabetic symptomatic71310,15
588 Antidiarrheal2569,702
589 Antidiuretic hormone agonist1510,249
590 Antidiuretic hormone antagonist12470,526
591 Antidote1226,815
592 Antidote, heavy metal481,81
593 Antidote, organophosphates40
594 Antidyskinetic2219,888
595 Antieczematic817,703
596 Antieczematic atopic33310,764
597 Antiemetic10234,171
598 Antiemphysemic2095,25
599 Antiepileptic24567,056
600 Antifibrinolytic1715,43
601 Antifungal20878,807
602 Antifungal (Pneumocystis)92,987
603 Antifungal enhancer204,444
604 Antiglaucomic13785,694
605 Anti-Helicobacter pylori1439,689
606 Antihelmintic4617,024
607 Antihelmintic (Fasciola)53,267
608 Antihelmintic (Nematodes)5610,496
609 Antihematotoxic3110,16
610 Antihemorrhagic165,385
611 Antihistaminic29694,749
612 Antihyperaldosteronism810,138
613 Antihyperammonemic30,197
614 Antihypercholesterolemic2487,382
615 Antihyperlipoproteinemic834,466
616 Antihypermotility774,668
617 Antihypertensive78749,933
618 Antihypertriglyceridemic1372,905
619 Antihypotensive389,978
620 Antihypoxic3813,373
621 Antiinfective17813,179
622 Antiinfertility, female677,432
623 Antiinflammatory598316,163
624 Antiinflammatory steroid30,006
625 Antiinflammatory, intestinal98,862
626 Antiinflammatory, ophthalmic5114,51
627 Antiischemic221010,218
628 Antiischemic, cerebral43922,758
629 Antileprosy566,104
630 Antileukemic49646,077
631 Antimetabolite7321,231
632 Antimetastatic2011,465
633 Antimigraine19805,625
634 Antimitotic19255,743
635 Antimitotic, Podophyllotoxin-like30,037
636 Antimutagenic344,135
637 Antimycobacterial72611,387
638 Antimycoplasmal376,469
639 Antimyopathies612,945
640 Antinaupathic175,037
641 Antineoplastic4962014
642 Antineoplastic (bladder cancer)3308,054
643 Antineoplastic (bone cancer)6810,854
644 Antineoplastic (brain cancer)51210,693
645 Antineoplastic (breast cancer)55697,08
646 Antineoplastic (carcinoma)19043,742
647 Antineoplastic (cervical cancer)20354,024
648 Antineoplastic (colon cancer)54574,807
649 Antineoplastic (colorectal cancer)56545,346
650 Antineoplastic (endocrine cancer)1679,079
651 Antineoplastic (gastric cancer)5416,067
652 Antineoplastic (glioblastoma multiforme)3478,444
653 Antineoplastic (glioma)4976,516
654 Antineoplastic (insulinoma)440,014
655 Antineoplastic (liver cancer)3638,186
656 Antineoplastic (lung cancer)29756,159
657 Antineoplastic (lymphocytic leukemia)28034,304
658 Antineoplastic (lymphoma)9796,454
659 Antineoplastic (melanoma)13976,232
660 Antineoplastic (multiple myeloma)19912,782
661 Antineoplastic (non-Hodgkin's lymphoma)7318,693
662 Antineoplastic (non-small cell lung cancer)8728,535
663 Antineoplastic (ovarian cancer)20064,955
664 Antineoplastic (pancreatic cancer)31211,833
665 Antineoplastic (renal cancer)4667,526
666 Antineoplastic (sarcoma)3208,776
667 Antineoplastic (small cell lung cancer)18612,361
668 Antineoplastic (solid tumors)70913,127
669 Antineoplastic (squamous cell carcinoma)12263,275
670 Antineoplastic (thyroid cancer)599,26
671 Antineoplastic (uterine cancer)1396,256
672 Antineoplastic alkaloid238,942
673 Antineoplastic antibiotic15992,166
674 Antineoplastic antimetabolite1664,928
675 Antineoplastic enhancer7749,187
676 Antineoplastic, alkylator1183,292
677 Antinephritic8314,859
678 Antineurogenic pain56111,555
679 Antineurotic4719,366
680 Antinociceptive4114,27
681 Antiobesity77698,827
682 Antiosteoporotic26667,339
683 Antioxidant8436,122
684 Antiparasitic6057,275
685 Antiparkinsonian276810,617
686 Antiparkinsonian, rigidity relieving377,312
687 Antiparkinsonian, tremor relieving1145,697
688 Antiperistaltic105,333
689 Antiprotozoal21918,48
690 Antiprotozoal (Amoeba)8813,152
691 Antiprotozoal (Babesia)52,614
692 Antiprotozoal (Coccidial)989,729
693 Antiprotozoal (Histomonas)70,375
694 Antiprotozoal (Leishmania)15112,068
695 Antiprotozoal (Plasmodium)13226,181
696 Antiprotozoal (Toxoplasma)217,964
697 Antiprotozoal (Trichomonas)898,17
698 Antiprotozoal (Trypanosoma)22512,137
699 Antiprotozoal activity enhancer50,001
700 Antipruritic26812,443
701 Antipruritic, allergic14614,962
702 Antipruritic, non-allergic686,137
703 Antipsoriatic177110,276
704 Antipsychotic66807,089
705 Antipyretic4108,141
706 Antirickettsial185,737
707 Antischistosomal395,658
708 Antiseborrheic109,308
709 Antisecretoric1929,274
710 Antiseptic1704,284
711 Antismoking1892,617
712 Antispirochetal353,71
713 Antithrombocytopenic1441,969
714 Antithrombotic55712,449
715 Antithyroid405,402
716 Antitoxic1459,506
717 Antitreponemal88,055
718 Antituberculosic43411,632
719 Antitussive2476,452
720 Antitussive, narcotic353,227
721 Antiulcerative89311,319
722 Antiuremic396,758
723 Antiviral113478,197
724 Antiviral (Adenovirus)2312,125
725 Antiviral (CMV)1513,052
726 Antiviral (Hepatitis B)539,631
727 Antiviral (Hepatitis C)14723,529
728 Antiviral (Hepatitis)17534,406
729 Antiviral (Herpes)14210,604
730 Antiviral (Herpesvirus 3, Human)70,001
731 Antiviral (HIV)70505,245
732 Antiviral (Influenza A)3112,674
733 Antiviral (Influenza)15011,74
734 Antiviral (Parainfluenza)50,008
735 Antiviral (Picornavirus)3118,954
736 Antiviral (Poxvirus)419,59
737 Antiviral (Rhinovirus)1319,345
738 Antiviral (Trachoma)121,278
739 Anxiolytic81218,971
740 Apical sodium codependent bile acid transporter inhibitor160,004
741 Apnea2410,389
742 APOA1 expression enhancer1717,426
743 Apolipoprotein A inhibitor710
744 Apolipoprotein B inhibitor2250,448
745 Apolipoprotein B-100 inhibitor500,151
746 Apoptosis agonist129913,455
747 Apoptosis antagonist2489,917
748 Apyrase inhibitor1718,198
749 AR expression inhibitor3112,267
750 Arabinogalactan endo-1,4-beta-galactosidase inhibitor40,18
751 Arabinose isomerase inhibitor70,657
752 Arabinose-5-phosphate isomerase inhibitor40,025
753 Arachidonate-CoA ligase inhibitor70,134
754 Arachidonic acid antagonist935,616
755 Aralkylamine dehydrogenase inhibitor60,075
756 Aralkylamine N-acetyltransferase inhibitor161,152
757 Arginase inhibitor340,702
758 Arginine 2-monooxygenase inhibitor410,473
759 Arginine decarboxylase inhibitor381,547
760 Arginine deiminase inhibitor225,272
761 Arginine kinase inhibitor120,485
762 Arginine N-succinyltransferase inhibitor30,025
763 Arginine racemase inhibitor30,058
764 Arginine-tRNA ligase inhibitor170,582
765 Argininosuccinate lyase inhibitor100,63
766 Argininosuccinate synthase inhibitor211,137
767 Arginyltransferase inhibitor60,615
768 Aromatase inhibitor12020,906
769 Aromatic-amino-acid transaminase inhibitor141,131
770 Aromatic-hydroxylamine O-acetyltransferase inhibitor714,927
771 Aryl hydrocarbon receptor agonist127,908
772 Aryl hydrocarbon receptor antagonist572,244
773 Aryl sulfotransferase inhibitor304,841
774 Arylacetonitrilase inhibitor113,577
775 Aryl-acylamidase inhibitor357,822
776 Aryl-alcohol dehydrogenase (NADP+) inhibitor71,461
777 Aryl-alcohol dehydrogenase inhibitor101,463
778 Aryl-aldehyde dehydrogenase (NADP+) inhibitor60,924
779 Arylalkyl acylamidase inhibitor61,194
780 Arylamine N-acetyltransferase inhibitor335,611
781 Arylamine N-Acetyltransferase substrate1031,456
782 Aryldialkylphosphatase inhibitor51,62
783 Arylesterase inhibitor96,486
784 Arylformamidase inhibitor281,598
785 Arylmalonate decarboxylase inhibitor32,726
786 Arylsulfatase inhibitor222,592
787 Arylsulfate sulfotransferase inhibitor79,066
788 Asparaginase inhibitor193,524
789 Asparagine synthase (glutamine-hydrolysing) inhibitor810,653
790 Asparagine-oxo-acid transaminase inhibitor170,53
791 Asparagine-tRNA ligase inhibitor60,992
792 Asparaginyl endopeptidase inhibitor540,759
793 Aspartate 1-decarboxylase inhibitor70,417
794 Aspartate 4-decarboxylase inhibitor191,678
795 Aspartate ammonia-lyase inhibitor260,537
796 Aspartate carbamoyltransferase inhibitor261,418
797 Aspartate kinase inhibitor244,842
798 Aspartate N-acetyltransferase inhibitor30,006
799 Aspartate racemase inhibitor40,583
800 Aspartate transaminase inhibitor211,522
801 Aspartate-ammonia ligase (ADP-forming) inhibitor40,631
802 Aspartate-ammonia ligase inhibitor32,362
803 Aspartate-phenylpyruvate transaminase inhibitor412,921
804 Aspartate-semialdehyde dehydrogenase inhibitor130,718
805 Aspartate-tRNA ligase inhibitor61,447
806 Aspartoacylase inhibitor41,479
807 Aspartyl aminopeptidase inhibitor81,138
808 Aspartyl protease inhibitor30,001
809 Aspartyltransferase inhibitor415,092
810 Aspergillopepsin I inhibitor86,98
811 Aspergillopepsin II inhibitor45,212
812 Aspergillus nuclease S1 inhibitor85,053
813 Aspulvinone dimethylallyltransferase inhibitor315,725
814 Assemblin inhibitor70,505
815 Astacin inhibitor191,485
816 Asthma20220,982
817 Astringent110,931
818 Ataxia43317,035
819 Atherosclerosis treatment367911,083
820 ATM kinase inhibitor741,67
821 ATP adenylyltransferase inhibitor71,467
822 ATP citrate lysase inhibitor470,372
823 ATP citrate synthase inhibitor200,342
824 ATP deaminase inhibitor50,297
825 ATP diphosphatase inhibitor40,464
826 ATP phosphoribosyltransferase inhibitor167,625
827 ATPase (Mitochondrial F1F0) inhibitor170,022
828 ATPase (Vacuolar H+) inhibitor730,705
829 ATPase inhibitor1506,726
830 ATPase stimulant1812,505
831 ATP-binding cassette A1 stimulant34,713
832 ATP-dependent RNA helicase inhibitor100,004
833 Atrolysin A inhibitor114,855
834 Atrolysin C inhibitor101,888
835 Attention deficit/hyperactivity disorder treatment6662,589
836 Aureolysin inhibitor41,618
837 Aurora kinase inhibitor9991,824
838 Aurora-A kinase inhibitor6001,774
839 Aurora-B kinase inhibitor5041,495
840 Aurora-C kinase inhibitor463,453
841 Autoimmune disorders treatment397212,095
842 Autophagy inducer36,623
843 Autotaxin inhibitor502,66
844 AXL receptor tyrosine kinase inhibitor405,808
845 Azobenzene reductase inhibitor51,446
846 Bacillus subtilis ribonuclease inhibitor60,367
847 Bacterial efflux pump inhibitor168,746
848 Bacterial leucyl aminopeptidase inhibitor290,693
849 Baculoviral IAP repeat-containing protein 4 inhibitor1180,859
850 Baculoviral IAP repeat-containing protein inhibitor1620,849
851 Bcl2 antagonist1347,003
852 Bcl-xL inhibitor1201,855
853 Bcr-Abl kinase inhibitor914,979
854 Behavioral disturbance153516,584
855 Benzaldehyde dehydrogenase (NAD+) inhibitor80,588
856 Benzaldehyde dehydrogenase (NADP+) inhibitor32,24
857 Benzoate 4-monooxygenase inhibitor196,156
858 Benzoate-CoA ligase inhibitor610,503
859 Benzodiazepine antagonist4551,149
860 Benzodiazepine inverse agonist590,876
861 Benzodiazepine receptor peripheral-type antagonist4250,331
862 Benzoin aldolase inhibitor30,035
863 Benzoylformate decarboxylase inhibitor910,578
864 Beta 1 adrenoreceptor agonist492,362
865 Beta 1 adrenoreceptor antagonist6771,115
866 Beta 2 adrenoreceptor agonist6830,523
867 Beta 2 adrenoreceptor antagonist6701,027
868 Beta 3 adrenoreceptor agonist7720,315
869 Beta 3 adrenoreceptor antagonist1561,24
870 Beta adrenoreceptor agonist15541,157
871 Beta adrenoreceptor antagonist14181,815
872 Beta amyloid protein antagonist1222,698
873 Beta galactosidase inhibitor810,65
874 Beta glucosidase inhibitor220,178
875 Beta glucuronidase inhibitor1513,066
876 Beta lactamase II inhibitor180,001
877 Beta lactamase Imi-1 inhibitor50,083
878 Beta lactamase inhibitor4373,739
879 Beta lactamase TEM-1 inhibitor420,062
880 Beta tubulin antagonist4780,929
881 Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase inhibitor130,67
882 Beta-adrenergic receptor kinase inhibitor2217,384
883 Beta-alanine-pyruvate transaminase inhibitor31,072
884 Beta-amylase inhibitor90,601
885 Beta-carotene 15,15'-monooxygenase inhibitor175,833
886 Beta-cyclopiazonate dehydrogenase inhibitor71,715
887 Beta-D-fucosidase inhibitor201,049
888 Beta-fructofuranosidase inhibitor430,856
889 Beta-galactoside alpha-2,3-sialyltransferase inhibitor100,152
890 Beta-glucosidase inhibitor591,125
891 Betaine-aldehyde dehydrogenase inhibitor180,736
892 Betaine-homocysteine S-methyltransferase inhibitor90,177
893 Beta-Lysine 5,6-aminomutase inhibitor40,254
894 Beta-mannosidase inhibitor101,369
895 Beta-N-acetylgalactosaminidase inhibitor31,546
896 Beta-N-acetylhexosaminidase inhibitor431,974
897 Beta-Phosphoglucomutase inhibitor50,103
898 Beta-ureidopropionase inhibitor162,976
899 Bile-salt sulfotransferase inhibitor41,334
900 Biliary tract disorders treatment9410,842
901 Bilirubin oxidase inhibitor98,284
902 Biliverdin reductase inhibitor110,638
903 Biotin carboxylase inhibitor41,376
904 Biotin-[methylmalonyl-CoA-carboxytransferase] ligase inhibitor40,041
905 Biotin-[propionyl-CoA-carboxylase (ATP-hydrolysing)] ligase inhibitor32,171
906 Biotin-CoA ligase inhibitor31,059
907 Biotinidase inhibitor816,118
908 Biphenyl-2,3-diol 1,2-dioxygenase inhibitor150,944
909 Bipolar disorder treatment1923,672
910 Bis(5'-adenosyl)-triphosphatase inhibitor40,922
911 Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) inhibitor120,399
912 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) inhibitor110,355
913 Bisphosphoglycerate mutase inhibitor41,574
914 Bisphosphoglycerate phosphatase inhibitor53,032
915 Bisphosphonate550,038
916 Blasticidin-S deaminase inhibitor42,242
917 Bombesin 1 receptor antagonist100,657
918 Bombesin 2 receptor antagonist191,882
919 Bombesin 3 receptor agonist240,518
920 Bombesin agonist250,405
921 Bombesin antagonist1481,12
922 Bone diseases treatment32817,713
923 Bone formation stimulant4767,974
924 Bone morphogenic protein 1 inhibitor1460,028
925 Bone morphogenic protein inhibitor1480,106
926 Bontoxilysin inhibitor64,89
927 Bothrolysin inhibitor31,76
928 Botulin neurotoxin A light chain inhibitor1113,049
929 Botulinum neurotoxin type B inhibitor80
930 Brachyurin inhibitor82,257
931 Bradycardic27519,877
932 Bradykinin agonist150,091
933 Bradykinin antagonist12080,427
934 Bradykinin B1 receptor agonist60
935 Bradykinin B1 receptor antagonist5680,28
936 Bradykinin B2 receptor agonist90,029
937 Bradykinin B2 receptor antagonist5450,1
938 BRAF expression inhibitor40,996
939 Branched-chain-amino-acid transaminase inhibitor210,567
940 Breast cancer-resistant protein inhibitor392,224
941 Bronchoconstrictor19818,68
942 Bronchodilator18134,154
943 Bruton tyrosine kinase inhibitor703,908
944 Bulimia treatment1030,274
945 Bullous pemphigoid83,84
946 Butyrate-CoA ligase inhibitor101,154
947 Butyrylcholinesterase inhibitor9521,096
948 Butyrylcholinesterase stimulant30,078
949 Butyryl-CoA dehydrogenase inhibitor90,37
950 Ca(v)2.2 blocker3441,647
951 Ca2+/calmodulin-dependent kinase I inhibitor188,545
952 Ca2+/calmodulin-dependent kinase II inhibitor863,941
953 Ca2+/calmodulin-dependent protein kinase inhibitor968,019
954 Ca2+-transporting ATPase inhibitor1213,918
955 Cachexia treatment1405,849
956 Cadherin antagonist30,039
957 Calcineurin inhibitor130,039
958 Calcitonin gene-related peptide 1 receptor antagonist2560,323
959 Calcitonin gene-related peptide antagonist6490,382
960 Calcitonin stimulant173,362
961 Calcium antagonist724,242
962 Calcium channel (voltage-sensitive) activator619,316
963 Calcium channel (voltage-sensitive) blocker22483,825
964 Calcium channel activator498,471
965 Calcium channel blocker43574,525
966 Calcium channel L-type blocker13791,425
967 Calcium channel N-type blocker6234,902
968 Calcium channel T-type blocker3441,664
969 Calcium regulator25916,13
970 Calcium release-activated channel blocker510,331
971 Calcium-sensing receptor agonist51,528
972 Calcium-sensing receptor antagonist870,762
973 Calpain inhibitor8636,744
974 Camphor 1,2-monooxygenase inhibitor41,554
975 Cancer associated disorders treatment4913,875
976 Cancer procoagulant inhibitor112,505
977 Candidapepsin 2 inhibitor100,014
978 Candidapepsin inhibitor172,767
979 Cannabinoid receptor antagonist19620,978
980 Capillary fragility treatment182,997
981 Carbamoyl-phosphate synthase (ammonia) inhibitor150,97
982 Carbamoyl-serine ammonia-lyase inhibitor30,096
983 Carbonic anhydrase I inhibitor8120,113
984 Carbonic anhydrase I stimulant560,05
985 Carbonic anhydrase II inhibitor12110,194
986 Carbonic anhydrase II stimulant590,713
987 Carbonic anhydrase inhibitor13440,238
988 Carbonic anhydrase IV inhibitor8100,113
989 Carbonic anhydrase IV stimulant500,009
990 Carbonic anhydrase IX inhibitor1560,101
991 Carbonic anhydrase stimulant740,88
992 Carbonic anhydrase V inhibitor750,947
993 Carbonic anhydrase VII inhibitor220,148
994 Carbonic anhydrase XII inhibitor340,075
995 Carbonic anhydrase XIV inhibitor182,083
996 Carbonic anhydrase XV inhibitor30
997 Carbon-monoxide dehydrogenase inhibitor32,443
998 Carboxy-cis,cis-muconate cyclase inhibitor190,206
999 Carboxycyclohexadienyl dehydratase inhibitor50,007
1000 Carboxylate reductase inhibitor60,241
1001 Carboxylesterase inhibitor432,016
1002 Carboxymethylenebutenolidase inhibitor30,556
1003 Carboxypeptidase B inhibitor390,42
1004 Carboxypeptidase D inhibitor94,719
1005 Carboxypeptidase E inhibitor215,516
1006 Carboxypeptidase M inhibitor60,399
1007 Carboxypeptidase Taq inhibitor37,366
1008 Carboxypeptidase U inhibitor170,66
1009 Carcinogenic18136,711
1010 Carcinogenic, group 12313,147
1011 Carcinogenic, group 2A364,508
1012 Carcinogenic, group 2B1943,975
1013 Carcinogenic, group 33875,21
1014 Carcinogenic, mouse4567,899
1015 Carcinogenic, mouse, female3848,48
1016 Carcinogenic, mouse, male3657,017
1017 Carcinogenic, rat6036,861
1018 Carcinogenic, rat, female4457,506
1019 Carcinogenic, rat, male5116,946
1020 Cardiac myosin stimulant40,001
1021 Cardiodepressant1608,521
1022 Cardioprotectant18711,548
1023 Cardiotonic322511,044
1024 Cardiovascular analeptic186,609
1025 Carminative42,215
1026 Carnitinamidase inhibitor74,287
1027 Carnitine 3-dehydrogenase inhibitor111,541
1028 Carnitine dehydratase inhibitor40,789
1029 Carnitine O-octanoyltransferase inhibitor71,673
1030 Carnitine palmitoyltransferase inhibitor231,699
1031 Carnosine synthase inhibitor144,253
1032 Caspase 2 inhibitor135,323
1033 Caspase 3 inhibitor6293,451
1034 Caspase 3 stimulant8318,982
1035 Caspase 6 inhibitor1260,081
1036 Caspase 7 inhibitor3030,038
1037 Caspase 8 inhibitor2420,653
1038 Caspase 8 stimulant3116,699
1039 Caspase 9 inhibitor373,139
1040 Catalase inhibitor273,928
1041 Catalase stimulant537,301
1042 Cataract11517,961
1043 Catechol 1,2-dioxygenase inhibitor200,905
1044 Catechol 2,3-dioxygenase inhibitor320,537
1045 Catechol O methyltransferase inhibitor581,841
1046 Catechol oxidase inhibitor152,52
1047 Catenin beta inhibitor3513,583
1048 Cathepsin B inhibitor6651,374
1049 Cathepsin D inhibitor6051,976
1050 Cathepsin E inhibitor383,377
1051 Cathepsin F inhibitor292,388
1052 Cathepsin G inhibitor974,075
1053 Cathepsin H inhibitor436,036
1054 Cathepsin K inhibitor6610,135
1055 Cathepsin L inhibitor6711,417
1056 Cathepsin S inhibitor6490,484
1057 Cathepsin T inhibitor75,276
1058 Cathepsin V inhibitor310,184
1059 CC chemokine 1 receptor antagonist2980,521
1060 CC chemokine 10 receptor antagonist100
1061 CC chemokine 2 receptor antagonist4131,433
1062 CC chemokine 3 receptor antagonist3390,66
1063 CC chemokine 4 receptor antagonist554,79
1064 CC chemokine 5 receptor agonist140,015
1065 CC chemokine 5 receptor antagonist4611,188
1066 CC chemokine 9 receptor antagonist232,385
1067 CC chemokine receptor 2B antagonist34,096
1068 CC chemokine receptor agonist151,598
1069 CC chemokine receptor antagonist15061,943
1070 CD45 antagonist962,106
1071 CD80 antagonist810
1072 CDC25 phosphatase inhibitor320,632
1073 CDC25A inhibitor902,599
1074 CDC25B inhibitor1471,798
1075 CDC25C inhibitor323,299
1076 CDC7 inhibitor940,444
1077 CDK/Cyclin complex inhibitor10902,087
1078 CDK1/cyclin B inhibitor3070,897
1079 CDK2/cyclin A inhibitor3793,603
1080 CDK2/cyclin A3 inhibitor300,003
1081 CDK2/cyclin E inhibitor4390,77
1082 CDK4/cyclin D inhibitor4250,445
1083 CDK4/cyclin D1 inhibitor2491,216
1084 CDK4/cyclin D3 inhibitor70,001
1085 CDK5/p25 inhibitor481,446
1086 CDK9/cyclin T1 inhibitor714,691
1087 CDP-4-dehydro-6-deoxyglucose reductase inhibitor41,437
1088 CDP-diacylglycerol diphosphatase inhibitor60,069
1089 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase inhibitor32,236
1090 CDP-diacylglycerol-inositol 3-phosphatidyltransferase inhibitor157,746
1091 CDP-diacylglycerol-serine O-phosphatidyltransferase inhibitor69,233
1092 CDP-glycerol diphosphatase inhibitor60,01
1093 CDP-glycerol glycerophosphotransferase inhibitor416,622
1094 Celiac disease treatment472,203
1095 Cell adhesion inhibitor6814,181
1096 Cell adhesion molecule inhibitor13514,006
1097 Cell wall biosynthesis inhibitor2011,493
1098 Cell wall synthesis inhibitor4434,01
1099 Cellobiose phosphorylase inhibitor100,71
1100 Cellulase inhibitor122,684
1101 Cellulose 1,4-beta-cellobiosidase inhibitor1110,589
1102 Cellulose synthase (UDP-forming) inhibitor1310,296
1103 Centromere associated protein inhibitor79,52
1104 Ceramidase inhibitor120,177
1105 Ceramide glucosyltransferase inhibitor184,631
1106 Cerebroside-sulfatase inhibitor91,925
1107 Cerebrovascular disordes treatment4787,616
1108 Cerevisin inhibitor81,155
1109 CF transmembrane conductance regulator agonist815,16
1110 CF transmembrane conductance regulator antagonist352,695
1111 Chalcone isomerase inhibitor260,477
1112 Channel-conductance-controlling ATPase inhibitor53,606
1113 Chaperonin ATPase inhibitor63,479
1114 Check point kinase 1 inhibitor4881,015
1115 Check point kinase 2 inhibitor1211,444
1116 Check point kinase inhibitor5671,071
1117 Chelator1172,791
1118 Chelator, Iron370,368
1119 Chemokine receptor agonist151,598
1120 Chemokine receptor antagonist22472,158
1121 Chemopreventive3455,811
1122 Chemoprotective1948,595
1123 Chemosensitizer20315,68
1124 Chenodeoxycholoyltaurine hydrolase inhibitor33,661
1125 Chitin deacetylase inhibitor30,061
1126 Chitin synthase inhibitor315,595
1127 Chitinase inhibitor2910,59
1128 Chitobiosyldiphosphodolichol beta-mannosyltransferase inhibitor51,658
1129 Chitosanase inhibitor85,452
1130 Chloramphenicol O-acetyltransferase inhibitor50,46
1131 Chlordecone reductase inhibitor48,88
1132 Chloride channel activator4111,868
1133 Chloride channel blocker104,967
1134 Chloride peroxidase inhibitor311,502
1135 Chloride/bicarbonate exchanger inhibitor240,851
1136 Cholate-CoA ligase inhibitor91,205
1137 Cholecystokinin A agonist1040,071
1138 Cholecystokinin A antagonist14770,532
1139 Cholecystokinin agonist1090,094
1140 Cholecystokinin antagonist20740,688
1141 Cholecystokinin B antagonist15010,545
1142 Choleretic1166,171
1143 Cholestanetriol 26-monooxygenase inhibitor98,759
1144 Cholestasis20617,123
1145 Cholestenol delta-isomerase inhibitor80,033
1146 Cholestenone 5alpha-reductase inhibitor128,258
1147 Cholesterol absorption inhibitor1922,354
1148 Cholesterol antagonist11912,368
1149 Cholesterol ester transfer protein antagonist5720,693
1150 Cholesterol esterase inhibitor1830,47
1151 Cholesterol monooxygenase (side-chain-cleaving) inhibitor70,002
1152 Cholesterol oxidase inhibitor151,632
1153 Cholesterol synthesis inhibitor813,284
1154 Choline acetyltransferase stimulant56,587
1155 Choline dehydrogenase inhibitor50,593
1156 Choline kinase inhibitor127,335
1157 Choline sulfotransferase inhibitor201,138
1158 Choline-phosphate cytidylyltransferase inhibitor1510,101
1159 Cholinergic39803,847
1160 Cholinergic antagonist40932,962
1161 Choline-sulfatase inhibitor82,572
1162 Choloylglycine hydrolase inhibitor31,507
1163 Chondroitin 6-sulfotransferase inhibitor41,171
1164 Chorea4510,07
1165 Choreoathetosis2911,5
1166 Chorismate mutase inhibitor220,218
1167 Chronic obstructive pulmonary disease treatment21616,739
1168 Chymase inhibitor1771,054
1169 Chymosin inhibitor312,297
1170 Chymotrypsin inhibitor2492,816
1171 Cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase inhibitor33,069
1172 Citrate (Si)-synthase inhibitor260,824
1173 Clavaminate synthase inhibitor32,527
1174 Cleft palate915,118
1175 Clostripain inhibitor225,757
1176 Cl--transporting ATPase inhibitor510,637
1177 CMP-KDO synthase inhibitor30,077
1178 CMP-N-acetylneuraminate monooxygenase inhibitor132,984
1179 CMP-N-acylneuraminate phosphodiesterase inhibitor231,414
1180 CNS active muscle relaxant1403,355
1181 Coactivator-associated arginine methyltransferase 1 inhibitor512,499
1182 Coagulant222,352
1183 Cocain dependency treatment2013,838
1184 Coccolysin inhibitor119,475
1185 Coenzyme-B sulfoethylthiotransferase inhibitor312,573
1186 Cognition disorders treatment674210,294
1187 Collagenase 3 inhibitor16991,005
1188 Collagenase inhibitor7531,188
1189 Colony stimulating factor agonist365,017
1190 Colony stimulating factor antagonist2782,881
1191 Colorectum cell-derived growth factor antagonist50,001
1192 Coma31117,401
1193 CO-methylating acetyl-CoA synthase inhibitor30
1194 Complement C5a chemotactic receptor antagonist1031,141
1195 Complement C5a convertase stimulant30,002
1196 Complement factor 1 inhibitor344,97
1197 Complement factor 1r inhibitor310,088
1198 Complement factor D inhibitor314,893
1199 Complement inhibitor5110,709
1200 Complement stimulant30,002
1201 Conjunctivitis34122,686
1202 Consciousness alteration57119,219
1203 Constipation treatment925,31
1204 Contraceptive7914,652
1205 Contraceptive female1196,926
1206 Contraceptive male1773,191
1207 Coproporphyrinogen oxidase inhibitor281,558
1208 Corneal wound healing stimulator111,169
1209 Corticosteroid antagonist37,549
1210 Corticosteroid side-chain-isomerase inhibitor53,068
1211 Corticosteroid-like520,137
1212 Corticotropin releasing factor 1 receptor antagonist7330,031
1213 Corticotropin releasing factor antagonist331,505
1214 Corticotropin-like30,917
1215 Cortisol sulfotransferase inhibitor140,196
1216 Cortisone alpha-reductase inhibitor40,012
1217 Cortisone beta-reductase inhibitor70,074
1218 CPB protease inhibitor30,064
1219 CpG-Oligodeoxynucleotides inhibitor270
1220 Creatinase inhibitor80,838
1221 Creatine kinase inhibitor302,621
1222 Creatininase inhibitor69,875
1223 Creatinine deaminase inhibitor30,893
1224 Crotonoyl-[acyl-carrier-protein] hydratase inhibitor31,575
1225 Cruzipain inhibitor1682,214
1226 c-Src kinase inhibitor14461,763
1227 CTGF expression inhibitor115,2
1228 CTP synthase inhibitor141,36
1229 Cushing's syndrome treatment763,014
1230 Cutinase inhibitor63,135
1231 CXC chemokine 1 receptor antagonist1130,668
1232 CXC chemokine 2 receptor antagonist1241,609
1233 CXC chemokine 3 receptor antagonist1550,74
1234 CXC chemokine 4 receptor antagonist1450,597
1235 CXC chemokine 5 receptor antagonist3280,015
1236 CXC chemokine L1/GRO-alpha antagonist170,001
1237 CXC chemokine receptor antagonist8691,124
1238 Cyanate hydratase inhibitor131,38
1239 Cyanoalanine nitrilase inhibitor515,74
1240 Cyanosis16216,426
1241 Cyclamate sulfohydrolase inhibitor40,942
1242 Cyclic AMP agonist1512,919
1243 Cyclic AMP modulator4010,603
1244 Cyclic AMP phosphodiesterase inhibitor18812,531
1245 Cyclic GMP phosphodiesterase inhibitor1912,003
1246 Cyclin-dependent kinase 1 inhibitor11431,443
1247 Cyclin-dependent kinase 2 inhibitor20021,681
1248 Cyclin-dependent kinase 4 inhibitor9580,974
1249 Cyclin-dependent kinase 5 inhibitor7000,979
1250 Cyclin-dependent kinase 6 inhibitor533,368
1251 Cyclin-dependent kinase 7 inhibitor533,483
1252 Cyclin-dependent kinase 9 inhibitor631,751
1253 Cyclin-dependent kinase inhibitor36652,21
1254 Cycloartenol synthase inhibitor193,461
1255 Cyclohexadienyl dehydrogenase inhibitor120,067
1256 Cyclohexanone monooxygenase inhibitor1115,009
1257 Cyclohexyl-isocyanide hydratase inhibitor31,881
1258 Cyclomaltodextrin glucanotransferase inhibitor170,049
1259 Cyclomaltodextrinase inhibitor616,448
1260 Cyclooxygenase 1 inhibitor13762,625
1261 Cyclooxygenase 1 substrate30,428
1262 Cyclooxygenase 2 inhibitor33702,278
1263 Cyclooxygenase 3 inhibitor180,277
1264 Cyclooxygenase inhibitor42163,405
1265 Cyclooxygenase substrate159,15
1266 Cyclopentanone monooxygenase inhibitor52,091
1267 Cyclopropane-fatty-acyl-phospholipid synthase inhibitor104,969
1268 CYP11B substrate70,001
1269 CYP11B1 inhibitor3130,853
1270 CYP11B1 substrate30,004
1271 CYP11B2 inhibitor3150,198
1272 CYP11B2 substrate60,002
1273 CYP17 inhibitor76,035
1274 CYP17 substrate101,433
1275 CYP17A substrate40,012
1276 CYP19 inducer30
1277 CYP19 inhibitor433,603
1278 CYP19 substrate232,576
1279 CYP19A1 expression inhibitor2415,479
1280 CYP19A1 substrate120,003
1281 CYP1A inducer458,307
1282 CYP1A inhibitor43511,393
1283 CYP1A substrate62011,286
1284 CYP1A1 inducer303,974
1285 CYP1A1 inhibitor837,84
1286 CYP1A1 substrate3288,042
1287 CYP1A2 inducer2411,055
1288 CYP1A2 inhibitor41210,987
1289 CYP1A2 substrate47711,768
1290 CYP1A3 substrate50,458
1291 CYP1B substrate836,854
1292 CYP1B1 inducer90,09
1293 CYP1B1 inhibitor622,504
1294 CYP1B1 substrate815,726
1295 CYP24 inhibitor118,787
1296 CYP24 substrate142,37
1297 CYP26 inhibitor190,69
1298 CYP26 substrate55,081
1299 CYP26A substrate46,443
1300 CYP27 substrate141,652
1301 CYP27A substrate122,02
1302 CYP27A1 inhibitor90,047
1303 CYP27A1 substrate80,008
1304 CYP2A substrate22811,345
1305 CYP2A1 substrate1613,887
1306 CYP2A10 substrate42,151
1307 CYP2A11 substrate32,462
1308 CYP2A13 substrate30,039
1309 CYP2A2 substrate84,145
1310 CYP2A3 substrate144,024
1311 CYP2A4 substrate39,305
1312 CYP2A5 inhibitor340,413
1313 CYP2A5 substrate86,313
1314 CYP2A6 inhibitor783,89
1315 CYP2A6 substrate20011,815
1316 CYP2A8 substrate34,416
1317 CYP2B substrate4428,786
1318 CYP2B1 substrate1795,128
1319 CYP2B10 substrate313,903
1320 CYP2B11 substrate107,263
1321 CYP2B18 substrate413,801
1322 CYP2B2 substrate778,823
1323 CYP2B4 substrate371,59
1324 CYP2B5 substrate34,664
1325 CYP2B6 substrate21311,118
1326 CYP2C substrate56412,974
1327 CYP2C10 substrate186,996
1328 CYP2C11 substrate868,692
1329 CYP2C12 substrate1015,042
1330 CYP2C18 inhibitor131,703
1331 CYP2C18 substrate357,935
1332 CYP2C19 inducer816,7
1333 CYP2C19 inhibitor36111,75
1334 CYP2C19 substrate27511,034
1335 CYP2C2 substrate54,171
1336 CYP2C29 substrate516,966
1337 CYP2C3 substrate613,969
1338 CYP2C6 substrate539,129
1339 CYP2C8 inducer92,924
1340 CYP2C8 inhibitor5518,642
1341 CYP2C8 substrate17015,226
1342 CYP2C9 inducer2718,014
1343 CYP2C9 inhibitor7489,928
1344 CYP2C9 substrate34212,774
1345 CYP2D substrate46111,119
1346 CYP2D1 substrate375,605
1347 CYP2D15 substrate518,392
1348 CYP2D16 substrate38,249
1349 CYP2D2 inhibitor77,053
1350 CYP2D6 inhibitor9946,41
1351 CYP2D6 substrate43811,182
1352 CYP2E substrate3709,272
1353 CYP2E1 inducer1213,885
1354 CYP2E1 inhibitor614,735
1355 CYP2E1 substrate3649,23
1356 CYP2F1 substrate85,477
1357 CYP2G1 substrate113,743
1358 CYP2H substrate315,386
1359 CYP2J substrate513,469
1360 CYP2J2 substrate413,754
1361 CYP3A inducer7412,709
1362 CYP3A substrate99314,724
1363 CYP3A1 substrate4814,011
1364 CYP3A11 substrate40,085
1365 CYP3A2 substrate5918,156
1366 CYP3A3 substrate3614,959
1367 CYP3A4 inducer7013,306
1368 CYP3A4 inhibitor13968,901
1369 CYP3A4 substrate84015,205
1370 CYP3A5 inducer42,47
1371 CYP3A5 substrate12514,922
1372 CYP3A7 substrate4111,433
1373 CYP3C substrate71,332
1374 CYP4A substrate3912,62
1375 CYP4A1 substrate80,863
1376 CYP4A11 substrate1713,006
1377 CYP4A2 substrate42,497
1378 CYP4B substrate165,488
1379 CYP4B1 substrate155,538
1380 CYP4F substrate211,826
1381 CYP4F12 substrate73,476
1382 CYP4F2 inhibitor340,493
1383 CYP4F2 substrate95,103
1384 CYP4F3 substrate100,007
1385 CYP4F8 substrate40,03
1386 CYP51 inhibitor140,208
1387 CYP7 inhibitor717,657
1388 CYP7 substrate80,008
1389 CYP7A1 substrate50,003
1390 CYP7B substrate40,034
1391 CYP7B1 substrate40,034
1392 Cystathionine beta-lyase inhibitor211,244
1393 Cystathionine beta-synthase inhibitor121,032
1394 Cystathionine gamma-lyase inhibitor261,006
1395 Cysteamine dioxygenase inhibitor91,98
1396 Cysteine desulfurase inhibitor50,903
1397 Cysteine dioxygenase inhibitor160,195
1398 Cysteine protease B inhibitor120,017
1399 Cysteine synthase inhibitor206,546
1400 Cysteine transaminase inhibitor30,287
1401 Cysteine-S-conjugate beta-lyase inhibitor30,617
1402 Cysteine-tRNA ligase inhibitor190,935
1403 Cystic fibrosis treatment23113,742
1404 Cystinyl aminopeptidase inhibitor355,654
1405 Cytidine deaminase inhibitor5113,524
1406 Cytidylate kinase inhibitor190,352
1407 Cytochrome P450 inhibitor32569,228
1408 Cytochrome P450 stimulant1718,321
1409 Cytochrome-b5 reductase inhibitor2112,759
1410 Cytochrome-b5 reductase substrate310,952
1411 Cytochrome-c3 hydrogenase inhibitor60,588
1412 Cytokine modulator1404,884
1413 Cytokine production inhibitor7574,175
1414 Cytokine production stimulant2601,473
1415 Cytokine release inhibitor71,12
1416 Cytoprotectant3715,813
1417 Cytosine deaminase inhibitor272,312
1418 Cytosol alanyl aminopeptidase inhibitor435,65
1419 Cytosole dipeptidase inhibitor50,948
1420 Cytosolic phospholipase A2 inhibitor1510,727
1421 Cytostatic3208,884
1422 Cytotoxic7216,919
1423 D(-)-tartrate dehydratase inhibitor50,048
1424 D-2-hydroxy-acid dehydrogenase inhibitor60,803
1425 Dactylysin inhibitor227,772
1426 D-Ala-D-Ala ligase inhibitor64,188
1427 D-alanine 2-hydroxymethyltransferase inhibitor31,503
1428 D-alanine transaminase inhibitor180,861
1429 D-Alanine-alanyl-poly(glycerolphosphate) ligase inhibitor50,015
1430 D-Alanine-poly(phosphoribitol) ligase inhibitor50,098
1431 D-amino-acid dehydrogenase inhibitor53,442
1432 D-Amino-acid oxidase inhibitor360,096
1433 D-arabinonolactone oxidase inhibitor50,852
1434 D-aspartate oxidase inhibitor180,132
1435 D-benzoylarginine-4-nitroanilide amidase inhibitor50,469
1436 dCMP deaminase inhibitor190,298
1437 dCTP deaminase inhibitor100,28
1438 dCTP diphosphatase inhibitor30
1439 D-cysteine desulfhydrase inhibitor50,89
1440 Deacetoxycephalosporin-C synthase inhibitor100,921
1441 Decylcitrate synthase inhibitor42,232
1442 Dehydro-L-gulonate decarboxylase inhibitor35,308
1443 Delayed rectifier potassium channel activator1620,838
1444 Delayed rectifier potassium channel blocker560,491
1445 Delirium10317,604
1446 DELTA14-sterol reductase inhibitor1310,552
1447 DELTA24-sterol reductase inhibitor712,209
1448 Dementia treatment1314,93
1449 Demethylmacrocin O-methyltransferase inhibitor100,021
1450 Demethylsterigmatocystin 6-O-methyltransferase inhibitor31,093
1451 Demyelination96,953
1452 Deoxyadenosine kinase inhibitor137,877
1453 Deoxycytidine deaminase inhibitor50,886
1454 Deoxycytidine kinase inhibitor432,527
1455 Deoxycytidylate 5-hydroxymethyltransferase inhibitor72,122
1456 Deoxyguanosine kinase inhibitor370,392
1457 Deoxyhypusine monooxygenase inhibitor160,169
1458 Deoxyhypusine synthase inhibitor271,356
1459 Deoxynucleoside kinase inhibitor240,023
1460 Deoxyribonuclease (pyrimidine dimer) inhibitor30,145
1461 Deoxyribonuclease I inhibitor105,023
1462 Deoxyribonuclease X inhibitor30,708
1463 Deoxyribose-phosphate aldolase inhibitor40,914
1464 Dependence7015,859
1465 Dependence treatment12176,022
1466 Depression12518,282
1467 Dermatitis87518,214
1468 Dermatologic345711,243
1469 Dethiobiotin synthase inhibitor71,286
1470 Dextranase inhibitor95,225
1471 Dextransucrase inhibitor180,611
1472 D-glutamate oxidase inhibitor90,938
1473 Diabetes insipidus treatment300,178
1474 Diabetic nephropathy treatment669,956
1475 Diabetic neuropathy treatment5718,443
1476 Diabetic retinopathy treatment2676,824
1477 Diacylglycerol cholinephosphotransferase inhibitor282,113
1478 Diacylglycerol kinase inhibitor236,056
1479 Diacylglycerol O-acyltransferase 1 inhibitor930,232
1480 Diacylglycerol O-acyltransferase inhibitor1411,515
1481 Diamine N-acetyltransferase inhibitor125,39
1482 Diamine oxidase inhibitor320,989
1483 Diaminopimelate decarboxylase inhibitor130,053
1484 Diaminopimelate dehydrogenase inhibitor70,743
1485 Diaminopimelate epimerase inhibitor80,132
1486 Diaminopropionate ammonia-lyase inhibitor110,814
1487 Diarrhea31618,339
1488 Dichloromethane dehalogenase inhibitor90,04
1489 Dichloromuconate cycloisomerase inhibitor40,393
1490 Diguanidinobutanase inhibitor60,598
1491 Dihydrodipicolinate reductase inhibitor810,47
1492 Dihydrodipicolinate synthase inhibitor160,56
1493 Dihydrofolate reductase (Mycobacterium avium) inhibitor110,025
1494 Dihydrofolate reductase (Pneumocystis carinii) inhibitor80,008
1495 Dihydrofolate reductase (Toxoplasma gondii) inhibitor110,067
1496 Dihydrofolate reductase inhibitor18120,726
1497 Dihydrofolate synthase inhibitor136,757
1498 Dihydrolipoamide S-acetyltransferase inhibitor40,62
1499 Dihydroneopterin aldolase inhibitor350,027
1500 Dihydroorotase inhibitor163,074
1501 Dihydroorotate dehydrogenase inhibitor1961,318
1502 Dihydroorotate oxidase inhibitor841,311
1503 Dihydropteroate synthase inhibitor311,362
1504 Dihydropyrimidinase inhibitor151,003
1505 Dihydropyrimidine dehydrogenase inhibitor81,477
1506 Dihydrouracil dehydrogenase (NAD+) inhibitor58,597
1507 Dihydrouracil oxidase inhibitor81,006
1508 Dihydroxyacetanilide dehydrogenase inhibitor50,034
1509 Dihydroxyacetanilide epoxidase inhibitor50,034
1510 Dihydroxy-acid dehydratase inhibitor145,314
1511 Diiodophenylpyruvate reductase inhibitor30,39
1512 Diiodotyrosine transaminase inhibitor60,091
1513 Diisopropyl-fluorophosphatase inhibitor50,938
1514 Dimethylallyltranstransferase inhibitor193,129
1515 Dimethylargininase inhibitor37,051
1516 Dimethylhistidine N-methyltransferase inhibitor50,767
1517 Dimethylmaleate hydratase inhibitor31,906
1518 Dipeptidase E inhibitor46,515
1519 Dipeptidyl peptidase I inhibitor682,061
1520 Dipeptidyl peptidase II inhibitor3501,121
1521 Dipeptidyl peptidase inhibitor16051,199
1522 Dipeptidyl peptidase IV inhibitor11950,985
1523 Dipeptidyl peptidase IX inhibitor1490,063
1524 Dipeptidyl peptidase VIII inhibitor2070,302
1525 Diphenylpicrylhydrazyl (DPPH) scavenger30,001
1526 Diphosphate-fructose-6-phosphate 1-phosphotransferase inhibitor170,269
1527 Diphosphate-serine phosphotransferase inhibitor80,064
1528 Diphosphomevalonate decarboxylase inhibitor136,677
1529 Di-trans,poly-cis-decaprenylcistransferase inhibitor42,23
1530 Diuretic7367,972
1531 Diuretic inhibitor9312,801
1532 Dizziness71918,797
1533 D-lactaldehyde dehydrogenase inhibitor1113,975
1534 D-lactate dehydrogenase (cytochrome) inhibitor70,905
1535 D-lactate dehydrogenase inhibitor712,455
1536 D-lactate-2-sulfatase inhibitor40,1
1537 D-Lysine 5,6-aminomutase inhibitor220,559
1538 D-malate dehydrogenase (decarboxylating) inhibitor100,933
1539 DNA damaging4663,673
1540 DNA directed DNA polymerase inhibitor3024,395
1541 DNA directed RNA polymerase inhibitor5436,26
1542 DNA directed RNA polymerase stimulant90,198
1543 DNA gyrase inhibitor2391,025
1544 DNA helicase inhibitor412,114
1545 DNA intercalator5821,971
1546 DNA ligase (ATP) inhibitor2110,578
1547 DNA methylase inhibitor412,703
1548 DNA methyltransferase I inhibitor104,703
1549 DNA nucleotidylexotransferase inhibitor214,645
1550 DNA polymerase I inhibitor2514,633
1551 DNA polymerase III inhibitor830,363
1552 DNA repair enzyme inhibitor1652,835
1553 DNA synthesis inhibitor29210,45
1554 DNA topoisomerase IV inhibitor1100,745
1555 DNA-(apurinic or apyrimidinic site) lyase inhibitor127,412
1556 DNA-3-methyladenine glycosylase I inhibitor53,926
1557 DNA-3-methyladenine glycosylase II inhibitor30,494
1558 DNA-dependent protein kinase inhibitor3090,538
1559 D-Octopine dehydrogenase inhibitor202,281
1560 Dolichol kinase inhibitor83,482
1561 Dolichyldiphosphatase inhibitor30,01
1562 Dolichyl-diphosphooligosaccharide-protein glycotransferase inhibitor37,829
1563 Dolichyl-phosphatase inhibitor61,309
1564 Dolichyl-phosphate beta-D-mannosyltransferase (T. brucei) inhibitor30,001
1565 Dolichyl-phosphate beta-D-mannosyltransferase inhibitor196,875
1566 Dolichyl-phosphate beta-glucosyltransferase inhibitor58,547
1567 DOPA decarboxylase inhibitor101,501
1568 Dopachrome isomerase inhibitor70,251
1569 Dopamine D1A antagonist250,062
1570 Dopamine D2 agonist inducer30
1571 Dopamine D2A antagonist821,421
1572 Dopamine D2B antagonist310,039
1573 Dopamine D2L antagonist4811,135
1574 Dopamine D2S antagonist1223,785
1575 Dopamine D5 antagonist2810,682
1576 Dopamine precursors250,048
1577 Dopamine release inhibitor30
1578 Dopamine release stimulant74,704
1579 Dopamine transporter inhibitor12210,939
1580 D-Ornithine 4,5-aminomutase inhibitor50,849
1581 D-proline reductase (dithiol) inhibitor50,574
1582 Drowsiness92618,149
1583 Dry eye syndrome treatment468,035
1584 D-Serine ammonia-lyase inhibitor40,084
1585 D-stereospecific aminopeptidase inhibitor70,432
1586 dTDP-glucose 4,6-dehydratase inhibitor60,02
1587 D-threo-aldose 1-dehydrogenase inhibitor76,311
1588 dTMP kinase (Mycobacterium tuberculosis) inhibitor110,017
1589 dTMP kinase inhibitor290,028
1590 Dual specificity phosphatase 1 inhibitor118,21
1591 Dual specificity phosphatase inhibitor1834,919
1592 Dual specificity protein phosphatase VHR inhibitor90,099
1593 dUTP diphosphatase inhibitor140,504
1594 D-xylulose reductase inhibitor41,419
1595 Dynamin GTPase inhibitor150,317
1596 Dynein ATPase inhibitor32,128
1597 Dyrk kinase inhibitor931,963
1598 Dysarthria10016,673
1599 Dyskinesia81715,928
1600 Dysmenorrhea treatment1662,634
1601 Dyspepsia treatment746,595
1602 Dysphoria3811,114
1603 Dyspnea31813,812
1604 Dystonia9618,945
1605 Ecdysone 20-monooxygenase inhibitor1513,372
1606 Edema14118,679
1607 Eicosanoid agonist60,211
1608 EIF4E expression inhibitor816,629
1609 Elastase 1 inhibitor581,227
1610 Elastase 2 inhibitor990,154
1611 Elastase inhibitor8341,23
1612 Electrolyte absorption antagonist544,526
1613 Electron transport complex I inhibitor261,508
1614 Electron-transferring-flavoprotein dehydrogenase inhibitor311,861
1615 Embryotoxic17439,348
1616 Emetic78817,962
1617 Endo-1,3(4)-beta-glucanase inhibitor30,869
1618 Endo-1,4-beta-xylanase inhibitor191,766
1619 Endo-beta-N-acetylglucosaminidase inhibitor70,022
1620 Endocannabinoid uptake inhibitor290,799
1621 Endocrine disruptor22314,834
1622 Endoglycosylceramidase inhibitor41,365
1623 Endometrios treatment2572,375
1624 Endonuclease (influenza) inhibitor110,733
1625 Endopeptidase inhibitor876,988
1626 Endopeptidase La inhibitor398,08
1627 Endopeptidase So inhibitor710,175
1628 Endothelial growth factor antagonist95,522
1629 Endothelial nitric-oxide synthase inhibitor2700,259
1630 Endothelin A receptor antagonist17560,329
1631 Endothelin B receptor antagonist14230,409
1632 Endothelin receptor agonist130,028
1633 Endothelin receptor antagonist27560,488
1634 Endothelin-converting enzyme inhibitor1124,78
1635 Endothiapepsin inhibitor50,269
1636 Enoyl-[acyl-carrier-protein] reductase (NADH) inhibitor1201,038
1637 Enoyl-CoA hydratase inhibitor90,464
1638 Enteropeptidase inhibitor616,574
1639 Envelysin inhibitor184,919
1640 EphB4 antagonist2801,178
1641 Ephrin antagonist3693,775
1642 Epidermal growth factor antagonist8930,926
1643 Epidermal growth factor receptor kinase inhibitor23263,727
1644 Epithelial sodium channel blocker500,789
1645 Epoxide hydrolase 2 inhibitor2810,157
1646 Epoxide hydrolase inhibitor6090,769
1647 Epoxide hydrolase substrate1472,132
1648 Equilibrative nucleoside transport protein 1 inhibitor970,451
1649 Equilibrative nucleoside transport protein inhibitor1270,455
1650 ErbB antagonist8411,666
1651 ErbB-1 antagonist121,501
1652 ErbB-2 antagonist7961,636
1653 ErbB-4 antagonist422,294
1654 Erectile dysfunction treatment3105,465
1655 Erythro-3-hydroxyaspartate ammonia-lyase inhibitor40,044
1656 Erythropoiesis stimulant615,172
1657 Erythropoietin receptor agonist100,011
1658 Estradiol 17 beta dehydrogenase 2 inhibitor812,275
1659 Estradiol 17 beta dehydrogenase 3 inhibitor1290,46
1660 Estradiol 17 beta dehydrogenase inhibitor3101,354
1661 Estradiol 17 beta dehydrogenase stimulant190,129
1662 Estradiol 17alpha-dehydrogenase inhibitor30,97
1663 Estrogen agonist7342,031
1664 Estrogen alpha receptor agonist440,565
1665 Estrogen antagonist22273,463
1666 Estrogen beta receptor agonist1850,369
1667 Estrogen receptor beta antagonist15242,761
1668 Estrogen-related receptor alpha antagonist430,946
1669 Estrone sulfatase inhibitor2400,303
1670 Estrone sulfotransferase inhibitor393,266
1671 Estrone sulfotransferase stimulant170,128
1672 Ethanolamine ammonia-lyase inhibitor100,062
1673 Ethanolamine kinase inhibitor151,14
1674 Ethanolamine oxidase inhibitor610,216
1675 Ethanolamine-phosphate cytidylyltransferase inhibitor76,951
1676 Ethanolaminephosphotransferase inhibitor283,918
1677 Ether-a-go-go potassium channel 1 blocker210,003
1678 Ether-a-go-go potassium channel blocker210,003
1679 Eukaryotic elongation factor 2 kinase inhibitor30
1680 Euphoria4315,962
1681 Excitability30017,94
1682 Excitatory amino acid transporter 1 inhibitor330,108
1683 Excitatory amino acid transporter 2 inhibitor440,063
1684 Excitatory amino acid transporter EAAC1 inhibitor60,88
1685 Exoribonuclease II inhibitor56,21
1686 Expectorant1326,712
1687 Extrapyramidal disorders treatment1204,095
1688 Extrapyramidal effect1213,432
1689 Eye irritation, high5286,277
1690 Eye irritation, inactive9110,326
1691 Eye irritation, moderate2293,257
1692 Eye irritation, weak3483,164
1693 Factor IXa inhibitor90,006
1694 Factor VII inhibitor1340,443
1695 Factor VIIa inhibitor2141,482
1696 Factor Xa inhibitor17410,71
1697 Factor XIa inhibitor65,733
1698 Factor XIIIa inhibitor521,702
1699 Factor XIIIa stimulant30,241
1700 FAD diphosphatase inhibitor170,704
1701 Falcipain 2 inhibitor1122,42
1702 Falcipain 3 inhibitor1410,367
1703 Falcipain inhibitor1122,42
1704 Farnesoid X receptor agonist960,531
1705 Farnesoid X receptor antagonist2211,575
1706 Farnesyltransferase inhibitor25181,229
1707 Farnesyltranstransferase inhibitor51,844
1708 Fas antagonist50,001
1709 Fasciculation2812,987
1710 Fatty acid elongase inhibitor182,002
1711 Fatty acid oxidation inhibitor450,566
1712 Fatty acid synthase inhibitor461,088
1713 Fatty liver4219,468
1714 Fatty-acyl-CoA synthase inhibitor56,472
1715 Fatty-acyl-ethyl-ester synthase inhibitor30,229
1716 Female sexual dysfunction treatment1272,884
1717 Ferredoxin hydrogenase inhibitor84,27
1718 Ferredoxin-NAD+ reductase inhibitor33,263
1719 Ferredoxin-NADP+ reductase inhibitor62,203
1720 Ferredoxin-nitrite reductase inhibitor124,408
1721 Ferrochelatase inhibitor51,04
1722 Feruloyl esterase inhibitor67,919
1723 Fibrillation, atrial1616,906
1724 Fibrinogen receptor antagonist2911,563
1725 Fibrinolytic3816,968
1726 Fibroblast activation protein alpha inhibitor360,046
1727 Fibroblast growth factor 1 agonist34,149
1728 Fibroblast growth factor 1 antagonist5792,135
1729 Fibroblast growth factor 2 antagonist1434,285
1730 Fibroblast growth factor 3 antagonist1773,235
1731 Fibroblast growth factor agonist47,295
1732 Fibroblast growth factor antagonist7852,436
1733 Fibrolase inhibitor410,925
1734 Fibromyalgia syndrome treatment536,378
1735 Fibrosis treatment954,551
1736 Fibrosis, interstitial813,861
1737 Flavin-containing monooxygenase inhibitor95,288
1738 Flavin-containing monooxygenase substrate6510,273
1739 FMN adenylyltransferase inhibitor70,007
1740 FMN reductase inhibitor224,935
1741 FMO1 substrate179,5
1742 FMO3 substrate3810,842
1743 Focal adhesion kinase 1 inhibitor384,986
1744 Focal adhesion kinase 2 inhibitor1408,426
1745 Focal adhesion kinase inhibitor2028,049
1746 Folate antagonist2113,023
1747 Folate transporter 1 inhibitor50,034
1748 Follicle-stimulating hormone agonist115,312
1749 Follicle-stimulating hormone antagonist540,032
1750 Folylpolyglutamate synthase inhibitor190,019
1751 Formaldehyde dehydrogenase (glutathione) inhibitor172,313
1752 Formaldehyde dehydrogenase inhibitor141,291
1753 Formaldehyde transketolase inhibitor67,972
1754 Formate C-acetyltransferase inhibitor50,216
1755 Formate dehydrogenase inhibitor212,218
1756 Formate-dihydrofolate ligase inhibitor1410,819
1757 Formimidoylglutamase inhibitor30,106
1758 Formimidoyltetrahydrofolate cyclodeaminase inhibitor80,86
1759 Formyl peptide receptor antagonist580,033
1760 Formyltetrahydrofolate dehydrogenase inhibitor60,835
1761 Fragilysin inhibitor614,197
1762 Free fatty acid receptor 1 agonist280,035
1763 Free radical scavenger2496,084
1764 Fructan beta-fructosidase inhibitor43,525
1765 Fructokinase inhibitor130,308
1766 Fructose 5-dehydrogenase (NADP+) inhibitor31,014
1767 Fructose 5-dehydrogenase inhibitor419,959
1768 Fructose-1,6-bisphosphatase inhibitor2110,113
1769 Fructose-2,6-bisphosphate 2-phosphatase inhibitor123,629
1770 Fructose-2,6-bisphosphate 6-phosphatase inhibitor40,331
1771 Fructuronate reductase inhibitor30,541
1772 FtsZ polymerization inhibitor50,023
1773 Fucokinase inhibitor90,354
1774 Fucosterol-epoxide lyase inhibitor96,742
1775 Fumarate hydratase inhibitor240,423
1776 Fumarate reductase (NADH) inhibitor710,64
1777 Fumarylacetoacetase inhibitor140,548
1778 Furin inhibitor231,756
1779 Fusarinine-C ornithinesterase inhibitor315,927
1780 G protein-coupled receptor agonist730,646
1781 GABA A inverse agonist810,783
1782 GABA A receptor agonist2315,493
1783 GABA A receptor antagonist27651,271
1784 GABA aminotransferase inhibitor1414,683
1785 GABA B receptor agonist108,118
1786 GABA B receptor antagonist630,602
1787 GABA C receptor agonist31,332
1788 GABA C receptor antagonist242,842
1789 GABA inverse agonist810,783
1790 GABA receptor agonist3866,632
1791 GABA receptor antagonist28351,301
1792 GABA transporter 1 inhibitor1500,444
1793 GABA transporter 2 inhibitor111,074
1794 GABA transporter 3 inhibitor80,996
1795 GABA transporter inhibitor1570,619
1796 GABA uptake inhibitor680,657
1797 Galactokinase inhibitor61,822
1798 Galactolipase inhibitor1210,015
1799 Galactorrhea1214,056
1800 Galactose 1-dehydrogenase (NADP+) inhibitor31,072
1801 Galactose oxidase inhibitor132,26
1802 Galactoside 2-alpha-L-fucosyltransferase inhibitor121,441
1803 Galactoside O-acetyltransferase inhibitor42,391
1804 Galactosylceramidase inhibitor81,532
1805 Galactosylceramide sulfotransferase inhibitor102,496
1806 Galactosylgalactosylglucosylceramidase inhibitor50,436
1807 Galacturan 1,4-alpha-galacturonidase inhibitor40,85
1808 Galectin 3 antagonist40,11
1809 Gallate decarboxylase inhibitor51,873
1810 Gametolysin inhibitor157,285
1811 Gamma-butyrobetaine dioxygenase inhibitor188,117
1812 Gamma-D-Glutamyl-meso-diaminopimelate peptidase inhibitor31,801
1813 Gamma-glutamyl hydrolase inhibitor420,683
1814 Gamma-glutamyltransferase inhibitor288,724
1815 Gamma-guanidinobutyraldehyde dehydrogenase inhibitor511,012
1816 Ganglioside galactosyltransferase inhibitor93,042
1817 Gastric antisecretory4897,906
1818 Gastric emptying disorders treatment993,864
1819 Gastric emptying impairment30,076
1820 Gastricsin inhibitor252
1821 Gastrin inhibitor8116,479
1822 Gastrin-releasing peptide antagonist503,477
1823 Gastritis treatment147,754
1824 Gastroesophageal reflux disease treatment2203,553
1825 Gastrointestinal disorders treatment2945,73
1826 Gastrointestinal disturbance17615,281
1827 Gastrointestinal hemorrhage1317,496
1828 Gastrointestinal motility stimulant797,328
1829 Gaucher disease treatment122,563
1830 GDP-L-fucose synthase inhibitor30,094
1831 GDP-mannose 4,6-dehydratase inhibitor80,033
1832 GDP-mannose 6-dehydrogenase inhibitor610,047
1833 Gelatinase inhibitor182,71
1834 General pump inhibitor4019,073
1835 Genotoxic1465,118
1836 Gentamicin 2''-nucleotidyltransferase inhibitor40,321
1837 Gentamicin 3'-N-acetyltransferase inhibitor120,202
1838 Gentisate 1,2-dioxygenase inhibitor61,201
1839 Geranylgeranyl-diphosphate geranylgeranyltransferase inhibitor93,859
1840 Geranylgeranyltransferase I inhibitor6680,494
1841 Geranylgeranyltransferase inhibitor7350,559
1842 Geranyltranstransferase (Leishmania) inhibitor270,012
1843 Geranyltranstransferase inhibitor1050,516
1844 Gestagen antagonist74,043
1845 Gestagen-like560,084
1846 GHS receptor agonist251,051
1847 GHS receptor antagonist1340,313
1848 Giant cell myocarditis30,327
1849 Gingipain K inhibitor65,957
1850 Gingipain R inhibitor71,307
1851 Glaucoma8615,905
1852 Globoside alpha-N-acetylgalactosaminyltransferase inhibitor133,586
1853 Glucagon receptor antagonist3620,643
1854 Glucagon-like peptide 1 agonist96,376
1855 Glucagon-like peptide 1 receptor antagonist300,138
1856 Glucan 1,3-alpha-glucosidase inhibitor190,684
1857 Glucan 1,3-beta-glucosidase inhibitor90,872
1858 Glucan 1,4-alpha-glucosidase inhibitor200,356
1859 Glucan 1,4-alpha-maltotetraohydrolase inhibitor32,217
1860 Glucan 1,4-alpha-maltotriohydrolase inhibitor33,831
1861 Glucan 1,4-beta-glucosidase inhibitor91,956
1862 Glucan 1,6-alpha-glucosidase inhibitor61,117
1863 Glucan endo-1,3-alpha-glucosidase inhibitor30,416
1864 Glucan endo-1,3-beta-D-glucosidase inhibitor1111,11
1865 Glucan endo-1,6-beta-glucosidase inhibitor78,601
1866 Glucarate dehydratase inhibitor50,913
1867 Glucocorticoid agonist3070,641
1868 Glucocorticoid antagonist9000,556
1869 Gluconate 2-dehydrogenase (acceptor) inhibitor419,897
1870 Gluconate 5-dehydrogenase inhibitor34,3
1871 Gluconate dehydratase inhibitor40,523
1872 Gluconokinase inhibitor32,687
1873 Gluconolactonase inhibitor32,115
1874 Glucosamine 6-phosphate N-acetyltransferase inhibitor60,423
1875 Glucosamine N-acetyltransferase inhibitor60,294
1876 Glucosamine-1-phosphate N-acetyltransferase inhibitor40,601
1877 Glucosamine-6-phosphate deaminase inhibitor121,738
1878 Glucose 1-dehydrogenase inhibitor81,448
1879 Glucose oxidase inhibitor714,5
1880 Glucose-1,6-bisphosphate synthase inhibitor110,254
1881 Glucose-1-phosphatase inhibitor30,833
1882 Glucose-1-phosphate adenylyltransferase inhibitor150,421
1883 Glucose-1-phosphate cytidylyltransferase inhibitor120,012
1884 Glucose-6-phosphate isomerase inhibitor220,136
1885 Glucose-6-phosphate translocase inhibitor250,251
1886 Glucose-dependent insulinotropic receptor agonist620,141
1887 Glucosyl transferase inhibitor365,22
1888 Glucosylceramidase inhibitor480,377
1889 Glucuronate isomerase inhibitor51,951
1890 Glucuronolactone reductase inhibitor31,101
1891 Glutamate (mGluR group I) agonist303,21
1892 Glutamate (mGluR group I) antagonist5652,068
1893 Glutamate (mGluR group II) agonist361,01
1894 Glutamate (mGluR group II) antagonist2730,057
1895 Glutamate (mGluR group III) agonist130,07
1896 Glutamate (mGluR group III) antagonist772,025
1897 Glutamate (mGluR) agonist831,241
1898 Glutamate (mGluR) antagonist8581,337
1899 Glutamate (mGluR1) agonist100,169
1900 Glutamate (mGluR1) antagonist2552,264
1901 Glutamate (mGluR1a) agonist40,013
1902 Glutamate (mGluR2) agonist300,19
1903 Glutamate (mGluR2) antagonist1970,115
1904 Glutamate (mGluR3) agonist110,472
1905 Glutamate (mGluR3) antagonist1540,085
1906 Glutamate (mGluR4) agonist50,727
1907 Glutamate (mGluR4) antagonist290,234
1908 Glutamate (mGluR5) agonist175,4
1909 Glutamate (mGluR5) antagonist4101,703
1910 Glutamate (mGluR5a) agonist40,013
1911 Glutamate (mGluR6) agonist80,086
1912 Glutamate (mGluR6) antagonist252,925
1913 Glutamate (mGluR8) agonist30,234
1914 Glutamate (mGluR8) antagonist421,828
1915 Glutamate 5-kinase inhibitor911,178
1916 Glutamate carboxypeptidase inhibitor210,994
1917 Glutamate decarboxylase inhibitor432,657
1918 Glutamate dehydrogenase (NADP+) inhibitor180,827
1919 Glutamate dehydrogenase [NAD(P)+] inhibitor451,181
1920 Glutamate dehydrogenase inhibitor344,049
1921 Glutamate formimidoyltransferase inhibitor110,311
1922 Glutamate N-acetyltransferase inhibitor40,873
1923 Glutamate racemase inhibitor720,321
1924 Glutamate receptor agonist3701,995
1925 Glutamate receptor antagonist60512,705
1926 Glutamate release inhibitor584,801
1927 Glutamate synthase (ferredoxin) inhibitor214,46
1928 Glutamate synthase (NADPH) inhibitor542,281
1929 Glutamate uptake inhibitor90,099
1930 Glutamate-1-semialdehyde 2,1-aminomutase inhibitor94,289
1931 Glutamate-5-semialdehyde dehydrogenase inhibitor411,294
1932 Glutamate-cysteine ligase inhibitor360,831
1933 Glutamate-tRNA ligase inhibitor617,433
1934 Glutamin-(asparagin-)ase inhibitor133,408
1935 Glutaminase inhibitor205,005
1936 Glutamine synthetase inhibitor383,477
1937 Glutamine-fructose-6-phosphate transaminase inhibitor40,582
1938 Glutamine-phenylpyruvate transaminase inhibitor33,335
1939 Glutamine-pyruvate transaminase inhibitor70,694
1940 Glutamine-tRNA ligase inhibitor91,086
1941 Glutaminyl-peptide cyclotransferase inhibitor1211,319
1942 Glutaminyl-tRNA synthase (glutamine-hydrolysing) inhibitor40,526
1943 Glutamyl endopeptidase II inhibitor315,971
1944 Glutarate-semialdehyde dehydrogenase inhibitor31,756
1945 Glutaryl-CoA dehydrogenase inhibitor51,246
1946 Glutathione dehydrogenase (ascorbate) inhibitor74,281
1947 Glutathione peroxidase inhibitor105,395
1948 Glutathione reductase (NADPH) stimulant112,483
1949 Glutathione reductase inhibitor465,054
1950 Glutathione reductase stimulant112,483
1951 Glutathione S-transferase inhibitor532,723
1952 Glutathione S-transferase substrate2183,652
1953 Glutathione synthase inhibitor151,726
1954 Glutathione thiolesterase inhibitor35,445
1955 Glutathione-disulfide reductase inhibitor461,479
1956 Glutathionylspermidine synthase inhibitor170,029
1957 Glyceraldehyde-3-phosphate dehydrogenase (NADP+) inhibitor123,844
1958 Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) inhibitor161,419
1959 Glyceraldehyde-3-phosphate dehydrogenase inhibitor231,547
1960 Glycerate kinase inhibitor120,087
1961 Glycerol 2-dehydrogenase (NADP+) inhibitor42,373
1962 Glycerol dehydratase inhibitor60,487
1963 Glycerol dehydrogenase (NADP+) inhibitor52,298
1964 Glycerol dehydrogenase inhibitor341,463
1965 Glycerol kinase inhibitor180,658
1966 Glycerol-1,2-cyclic-phosphate 2-phosphodiesterase inhibitor70,085
1967 Glycerol-1-phosphatase inhibitor30,781
1968 Glycerol-3-phosphate dehydrogenase (NAD+) inhibitor211,939
1969 Glycerol-3-phosphate dehydrogenase [NAD(P)+] inhibitor60,113
1970 Glycerol-3-phosphate dehydrogenase inhibitor289,316
1971 Glycerol-3-phosphate O-acyltransferase inhibitor235,177
1972 Glycerol-3-phosphate oxidase inhibitor617,326
1973 Glycerone-phosphate O-acyltransferase inhibitor101,543
1974 Glycerophosphocholine cholinephosphodiesterase inhibitor60,576
1975 Glycerophosphocholine phosphodiesterase inhibitor80,379
1976 Glyceryl-ether monooxygenase inhibitor1112,889
1977 Glycine amidinotransferase inhibitor54,475
1978 Glycine C-acetyltransferase inhibitor129,224
1979 Glycine dehydrogenase (decarboxylating) inhibitor31,397
1980 Glycine hydroxymethyltransferase inhibitor303,512
1981 Glycine N-acyltransferase inhibitor60,884
1982 Glycine N-benzoyltransferase inhibitor60,994
1983 Glycine N-choloyltransferase inhibitor100,569
1984 Glycine N-methyltransferase inhibitor90,596
1985 Glycine receptor agonist135,99
1986 Glycine receptor antagonist773,291
1987 Glycine transaminase inhibitor70,632
1988 Glycine transporter 1 inhibitor4660,321
1989 Glycine transporter 2 inhibitor741,575
1990 Glycine transporter inhibitor5500,779
1991 Glycine-tRNA ligase inhibitor109,284
1992 Glycogen (starch) synthase inhibitor265,477
1993 Glycogen synthase kinase-3 alpha inhibitor3451,061
1994 Glycogen synthase kinase-3 beta inhibitor8821,846
1995 Glycogen synthase kinase-3 inhibitor12151,828
1996 Glycogen synthase stimulant912,932
1997 Glycogenin glucosyltransferase inhibitor80,265
1998 Glycolaldehyde dehydrogenase inhibitor60,602
1999 Glycolate dehydrogenase inhibitor32,53
2000 Glycolipid 2-alpha-mannosyltransferase inhibitor90,221
2001 Glycolipid 3-alpha-mannosyltransferase inhibitor120,265
2002 Glycopeptide alpha-N-acetylgalactosaminidase inhibitor81,368
2003 Glycoprotein 3-alpha-L-fucosyltransferase inhibitor102,297
2004 Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase inhibitor94,35
2005 Glycosylceramidase inhibitor140,716
2006 Glycosylphosphatidylinositol diacylglycerol-lyase inhibitor172,699
2007 Glycosylphosphatidylinositol phospholipase D inhibitor412,027
2008 Glyoxylate oxidase inhibitor32,292
2009 Glyoxylate reductase (NADP+) inhibitor127,056
2010 Glyoxylate reductase inhibitor47,692
2011 Gly-X carboxypeptidase inhibitor61,374
2012 GMP reductase inhibitor170,323
2013 GMP synthase inhibitor571,525
2014 Gonadotropin antagonist2413,378
2015 Gout treatment1175,979
2016 GP IIb/IIIa receptor antagonist20680,887
2017 G-protein-coupled bile acid receptor 1 agonist93,947
2018 G-protein-coupled receptor 120 agonist100,009
2019 G-protein-coupled receptor kinase inhibitor2217,384
2020 Granulocyte macrophage colony stimulating factor agonist122,566
2021 Granulocyte stimulating factor agonist300,002
2022 Granzyme A inhibitor92,336
2023 Granzyme B inhibitor233,088
2024 Growth factor agonist2448,277
2025 Growth factor antagonist35283,183
2026 Growth factor receptor-bound protein 2 antagonist720,006
2027 Growth hormone agonist104,728
2028 Growth hormone release inhibitor691,723
2029 Growth hormone release promoting581,713
2030 Growth hormone releasing factor agonist4450,409
2031 Growth hormone releasing factor antagonist380,03
2032 Growth stimulant616,134
2033 GRP78 expression inhibitor50,012
2034 GST A substrate129,566
2035 GST M substrate137,516
2036 GST M1-1 substrate88,994
2037 GST P substrate154,448
2038 GST P1-1 substrate144,202
2039 GST T substrate84,932
2040 GST T1-1 substrate84,932
2041 GTP cyclohydrolase I inhibitor150,611
2042 GTP cyclohydrolase IIa inhibitor60,006
2043 Guanidinoacetase inhibitor61,951
2044 Guanidinoacetate kinase inhibitor129,067
2045 Guanidinoacetate N-methyltransferase inhibitor61,91
2046 Guanidinobutyrase inhibitor130,746
2047 Guanidinodeoxy-scyllo-inositol-4-phosphatase inhibitor30,618
2048 Guanidinopropionase inhibitor50,504
2049 Guanine deaminase inhibitor131,704
2050 Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase inhibitor47,961
2051 Guanylate cyclase 1 inhibitor80,003
2052 Guanylate cyclase 1 stimulant106,91
2053 Guanylate cyclase inhibitor963,783
2054 Guanylate cyclase stimulant744,287
2055 Guanylate kinase inhibitor150,874
2056 Gynecological disorders treatment6792,57
2057 H+/K+-transporting ATPase inhibitor6012,053
2058 H+-exporting ATPase inhibitor127,295
2059 H+-transporting two-sector ATPase inhibitor69,168
2060 Hair growth stimulant5083,294
2061 Haloacetate dehalogenase inhibitor30,524
2062 Haloalkane dehalogenase inhibitor40,209
2063 HCV IRES inhibitor913,191
2064 HCV NS3/NS4A protease inhibitor6171,583
2065 HCV NS3-helicase inhibitor863,116
2066 HCV NS5A inhibitor200,01
2067 HCV NS5B polymerase inhibitor5240,524
2068 HDL-cholesterol increasing1754,676
2069 Headache83818,686
2070 Heart failure treatment15655,384
2071 Heat shock protein 27 antagonist918,403
2072 Heat shock protein 70 agonist245,561
2073 Heat shock protein 70 antagonist233,626
2074 Heat shock protein 90 antagonist3322,439
2075 Heat shock protein agonist257,965
2076 Heat shock protein antagonist3642,984
2077 Hedgehog signaling activator40
2078 Hedgehog signaling inhibitor832,917
2079 Helicase E1 (Human papillomavirus) inhibitor280,017
2080 Hematemesis716,824
2081 Hematinic136,633
2082 Hematopoietic6810,031
2083 Hematopoietic inhibitor188,919
2084 Hematotoxic114217,343
2085 Hematuria4314,81
2086 Heme oxygenase inhibitor719,672
2087 Heme oxygenase stimulant101,393
2088 Hemostatic10110,166
2089 Heparan-alpha-glucosaminide N-acetyltransferase inhibitor121,387
2090 Heparanase inhibitor601,547
2091 Heparin epidermal growth factor antagonist1140,04
2092 Hepatic disorders treatment70610,361
2093 Hepatitis39720,239
2094 Hepatocyte growth factor agonist712,781
2095 Hepatocyte growth factor antagonist5262,266
2096 Hepatocyte nuclear factor 4 alpha agonist60,038
2097 Hepatocyte nuclear factor 4 alpha antagonist67,917
2098 Hepatocyte nuclear factor agonist60,038
2099 Hepatocyte nuclear factor antagonist67,917
2100 Hepatoprotectant2919,666
2101 Hepatotoxic103316,297
2102 HERG 1 channel blocker385,886
2103 HERG channel blocker12074,804
2104 Hexokinase inhibitor1934,432
2105 Hexokinase stimulant1190,889
2106 HIF1A expression inhibitor2317,1
2107 High-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase inhibitor30,175
2108 Hippurate hydrolase inhibitor40,782
2109 Hirsutism treatment821,537
2110 Histamine agonist1186,331
2111 Histamine antagonist27203,639
2112 Histamine H1 receptor agonist51,52
2113 Histamine H1 receptor antagonist8582,285
2114 Histamine H2 receptor agonist362,111
2115 Histamine H2 receptor antagonist3751,814
2116 Histamine H3 receptor agonist550,058
2117 Histamine H3 receptor antagonist14470,564
2118 Histamine H4 receptor antagonist1310,45
2119 Histamine N-methyltransferase inhibitor691,927
2120 Histamine release inhibitor11814,001
2121 Histamine release stimulant2110,712
2122 Histidine ammonia-lyase inhibitor341,56
2123 Histidine decarboxylase inhibitor331,978
2124 Histidine kinase inhibitor47,544
2125 Histidine N-acetyltransferase inhibitor618,192
2126 Histidine-tRNA ligase inhibitor190,603
2127 Histidinol dehydrogenase inhibitor216,535
2128 Histidinol-phosphatase inhibitor62,692
2129 Histone acetylation inducer90
2130 Histone acetyltransferase inhibitor438,175
2131 Histone deacetylase 1 inhibitor8870,456
2132 Histone deacetylase 1A inhibitor80,043
2133 Histone deacetylase 1B inhibitor360,011
2134 Histone deacetylase 2 inhibitor5230,537
2135 Histone deacetylase 3 inhibitor5330,693
2136 Histone deacetylase 4 inhibitor4870,607
2137 Histone deacetylase 6 inhibitor7190,31
2138 Histone deacetylase 8 inhibitor3120,848
2139 Histone deacetylase class I inhibitor11330,491
2140 Histone deacetylase class II inhibitor8110,433
2141 Histone deacetylase class IIa inhibitor4970,597
2142 Histone deacetylase class IIb inhibitor7260,309
2143 Histone deacetylase class III inhibitor563,467
2144 Histone deacetylase inhibitor19241,128
2145 Histone deacetylase SIRT1 inhibitor384,38
2146 Histone deacetylase SIRT1 stimulant630,584
2147 Histone deacetylase SIRT2 inhibitor422,935
2148 Histone deacetylase SIRT2 stimulant50,106
2149 Histone deacetylase stimulant630,584
2150 Histone-arginine N-methyltransferase inhibitor90,587
2151 Histone-lysine N-methyltransferase inhibitor170,083
2152 HIV attachment inhibitor1311,005
2153 HIV fusion inhibitor40
2154 HIV-1 integrase (3'-Processing) inhibitor3581,548
2155 HIV-1 integrase (Overall Integration) inhibitor552,258
2156 HIV-1 integrase (Strand Transfer) inhibitor3551,398
2157 HIV-1 integrase inhibitor8842,067
2158 HIV-1 protease inhibitor26150,865
2159 HIV-1 reverse transcriptase inhibitor21061,211
2160 HIV-2 retropepsin inhibitor160,096
2161 HIV-2 reverse transcriptase inhibitor31,487
2162 HLA-A2 antigen antagonist1880,084
2163 HMG CoA reductase inhibitor4840,819
2164 HMG CoA synthase inhibitor51,992
2165 HMGCS2 expression enhancer58,021
2166 HMOX1 expression enhancer699,666
2167 Homoaconitate hydratase inhibitor31,059
2168 Homocitrate synthase inhibitor181,794
2169 Homocysteine desulfhydrase inhibitor80,987
2170 Homocysteine S-methyltransferase inhibitor40,517
2171 Homogentisate 1,2-dioxygenase inhibitor124,479
2172 Homoisocitrate dehydrogenase inhibitor30,006
2173 Homoserine dehydrogenase inhibitor1410,864
2174 Homoserine kinase inhibitor241,557
2175 Homoserine O-acetyltransferase inhibitor110,232
2176 Homoserine O-succinyltransferase inhibitor30,225
2177 Homospermidine synthase inhibitor40,514
2178 Horrilysin inhibitor31,544
2179 Hot flush treatment911,605
2180 Huntington's disease treatment1434,894
2181 Hyaluronic acid agonist37,541
2182 Hydrogen dehydrogenase inhibitor310,044
2183 Hydroperoxide dehydratase inhibitor120,962
2184 Hydroxyacylglutathione hydrolase inhibitor552,457
2185 Hydroxylamine oxidase inhibitor69,437
2186 Hydroxylamine reductase (NADH) inhibitor1812,524
2187 Hydroxylamine reductase inhibitor613,675
2188 Hydroxylysine kinase inhibitor90,267
2189 Hydroxymethylbilane synthase inhibitor113,936
2190 Hydroxymethylglutaryl-CoA lyase inhibitor74,657
2191 Hydroxymethylglutaryl-CoA reductase inhibitor50,468
2192 Hydroxypyruvate reductase inhibitor170,364
2193 Hydroxyquinol 1,2-dioxygenase inhibitor90,304
2194 Hydroxysteroid dehydrogenase inhibitor46,355
2195 Hypercalcaemic1915,301
2196 Hypercalcemia treatment434,158
2197 Hypercholesterolemic1014,886
2198 Hyperglycemic7119,894
2199 Hyperparathyroidism treatment681,548
2200 Hyperprolactinemia treatment92,404
2201 Hypertensive73618,509
2202 Hypertensive, ophthalmic104,222
2203 Hyperthermic26315,609
2204 Hyperuricemia45,291
2205 Hypnotic7157,696
2206 Hypocalcaemic2914,611
2207 Hypoglycemic4138,118
2208 Hypogonadism treatment1250,116
2209 Hypolipemic201410,836
2210 Hypomagnesemia36,242
2211 Hypomania225,638
2212 Hyponitrite reductase inhibitor32,194
2213 Hypotension105316,766
2214 Hypothermic29515,586
2215 Hypotonia9819,986
2216 Hypoxanthine phosphoribosyltransferase inhibitor371,045
2217 Hypoxia inducible factor 1 alpha inhibitor605,624
2218 I kappa B kinase 2 inhibitor3102,68
2219 I kappa B kinase inhibitor3873,474
2220 I(Ks) voltage-gated potassium channel blocker380,045
2221 ICAM 1 antagonist3890,45
2222 ICAM1 expression inhibitor5811,933
2223 Iduronate-2-sulfatase inhibitor30,485
2224 IgA-specific metalloendopeptidase inhibitor92,485
2225 IgA-specific serine endopeptidase inhibitor54,685
2226 Ileal bile acid transport inhibitor1440,167
2227 Imidazoleacetate 4-monooxygenase inhibitor131,041
2228 Imidazoleglycerol-phosphate dehydratase inhibitor50,187
2229 Imidazoline I1 receptor agonist32,138
2230 Imidazoline I1 receptor antagonist520,037
2231 Imidazoline I2 receptor antagonist1400,031
2232 Imidazoline receptor agonist62,847
2233 Imidazoline receptor antagonist1580,055
2234 Immunoglobulin E antagonist395,828
2235 Immunoglobulin Fc receptor antagonist365,332
2236 Immunomodulator148410,831
2237 Immunostimulant6759,368
2238 Immunosuppressant209012,9
2239 IMP cyclohydrolase inhibitor100,017
2240 Indanol dehydrogenase inhibitor137,513
2241 Indole-3-acetaldehyde reductase (NADPH) inhibitor110,727
2242 Indoleacetaldoxime dehydratase inhibitor127,745
2243 Indoleamine-pyrrole 2,3-dioxygenase inhibitor1311,753
2244 Indolepyruvate C-methyltransferase inhibitor42,624
2245 Inducible nitric-oxide synthase inhibitor4412,307
2246 Inflammation44219,376
2247 Inflammatory Bowel disease treatment127210,941
2248 Inorganic diphosphatase inhibitor284,396
2249 Inosine kinase inhibitor40,013
2250 Inosine monophosphate dehydrogenase 1 inhibitor690,082
2251 Inosine monophosphate dehydrogenase 2 inhibitor3460,033
2252 Inosine monophosphate dehydrogenase inhibitor4520,226
2253 Inosine nucleosidase inhibitor40,919
2254 Inosine-adenosine-guanosine-nucleoside hydrolase inhibitor40,002
2255 Inositol 1,4,5-triphosphate receptor 1 antagonist100,004
2256 Inositol 1,4,5-triphosphate receptor antagonist123,716
2257 Inositol 1,4,5-trisphosphate 3-kinase B inhibitor111,354
2258 Inositol 1,4,5-trisphosphate 3-kinase inhibitor155,114
2259 Inositol oxygenase inhibitor344,671
2260 Inositol polyphosphate-5-phosphatase D stimulant70,017
2261 Inositol-3-phosphate synthase inhibitor200,766
2262 Inositol-polyphosphate 5-phosphatase inhibitor191,493
2263 Inotropic3612,585
2264 Insecticide1933,935
2265 Insulin antagonist3393,283
2266 Insulin growth factor antagonist5321,62
2267 Insulin like growth factor 1 antagonist4881,902
2268 Insulin like growth factor 3 antagonist440,001
2269 Insulin promoter4317,089
2270 Insulin secretagoues2494,074
2271 Insulin sensitizer2243,158
2272 Insulysin inhibitor4914,368
2273 Integrin alpha1beta1 antagonist420,605
2274 Integrin alpha2 antagonist351,753
2275 Integrin alpha2beta1 antagonist252,118
2276 Integrin alpha4 antagonist21460,212
2277 Integrin alpha4beta1 antagonist9410,324
2278 Integrin alpha4beta7 antagonist6020,221
2279 Integrin alpha5beta1 antagonist1630,897
2280 Integrin alpha5beta6 antagonist140,007
2281 Integrin alphaLbeta2 antagonist380,036
2282 Integrin alphaVbeta1 antagonist174,445
2283 Integrin alphaVbeta3 antagonist141,148
2284 Integrin alphaVbeta5 antagonist3070,165
2285 Integrin alphaVbeta6 antagonist790,146
2286 Integrin antagonist40420,83
2287 Integrin-linked kinase inhibitor130,002
2288 Interferon agonist1343,489
2289 Interferon alpha agonist44,385
2290 Interferon antagonist854,449
2291 Interferon gamma antagonist844,046
2292 Interferon inducer1121,609
2293 Interleukin 1 antagonist9194,733
2294 Interleukin 1 beta converting enzyme inhibitor2891,053
2295 Interleukin 10 agonist379,261
2296 Interleukin 10 antagonist63,337
2297 Interleukin 12 agonist1303,757
2298 Interleukin 1a antagonist176,216
2299 Interleukin 1b antagonist4993,192
2300 Interleukin 2 agonist1512,997
2301 Interleukin 2 antagonist2284,552
2302 Interleukin 4 antagonist1464,877
2303 Interleukin 5 antagonist1313,79
2304 Interleukin 6 antagonist2147,399
2305 Interleukin 8 antagonist2094,931
2306 Interleukin agonist1776,262
2307 Interleukin antagonist15667,086
2308 Intermittent claudication treatment1716,498
2309 Interstitial nephritis9718,054
2310 Inulinase inhibitor41,229
2311 Iodide peroxidase inhibitor212,934
2312 Iron antagonist80,384
2313 Iron-cytochrome-c reductase inhibitor31,251
2314 Irritable Bowel syndrome treatment14235,466
2315 Irritation658,462
2316 Isoamylase inhibitor150,94
2317 Isocitrate dehydrogenase (NAD+) inhibitor282,409
2318 Isocitrate dehydrogenase (NADP+) inhibitor240,855
2319 Isocitrate lyase inhibitor261,515
2320 Isoleucine-tRNA ligase inhibitor251,269
2321 Isomaltulose synthase inhibitor60,629
2322 Isopenicillin-N epimerase inhibitor913,405
2323 Isopenicillin-N synthase inhibitor82,72
2324 Isopentenyl-diphosphate DELTA-isomerase inhibitor220,147
2325 Isoquinoline 1-oxidoreductase inhibitor41,576
2326 Isovaleryl-CoA dehydrogenase inhibitor61,318
2327 JAK2 expression inhibitor48,032
2328 Janus tyrosine kinase 1 inhibitor592,749
2329 Janus tyrosine kinase 2 inhibitor3815,445
2330 Janus tyrosine kinase 3 inhibitor4061,388
2331 Janus tyrosine kinase inhibitor7683,956
2332 JNK mitogen-activated protein kinase inhibitor434,822
2333 Juvenile-hormone esterase inhibitor860,071
2334 K(Ca) 3.1 channel activator41,308
2335 K(Ca) 3.1 channel blocker411,617
2336 K(ir) 6.2 channel activator134,936
2337 Kainate receptor 1 agonist50,158
2338 Kainate receptor 1 antagonist2960,231
2339 Kainate receptor 2 antagonist1350,508
2340 Kainate receptor 3 antagonist1400,22
2341 Kainate receptor 4 antagonist1340,278
2342 Kainate receptor 5 antagonist1520,283
2343 Kainate receptor agonist260,804
2344 Kainate receptor antagonist4610,582
2345 Kallikrein 13 inhibitor100,121
2346 Kallikrein 3 inhibitor290,885
2347 Kallikrein inhibitor944,309
2348 Kanamycin kinase inhibitor30,008
2349 Keratan sulfotransferase inhibitor70,099
2350 Keratolytic345,504
2351 Keratopathy9216,246
2352 Keratoses actinic (solar) treatment684,664
2353 Ketohexokinase inhibitor155,782
2354 Ketol-acid reductoisomerase inhibitor107,82
2355 Ketosteroid monooxygenase inhibitor50,015
2356 Kexin inhibitor161,655
2357 Kidney function stimulant714,945
2358 Kinase inhibitor1113,333
2359 Kinesin antagonist3740,796
2360 Kinesin-like protein 1 inhibitor3740,796
2361 KiSS-1 receptor agonist30,001
2362 Kynureninase inhibitor421,211
2363 Kynurenine 3 monooxygenase inhibitor700,086
2364 L lactate dehydrogenase A inhibitor160,002
2365 L lactate dehydrogenase A4 inhibitor150,002
2366 L lactate dehydrogenase B inhibitor60,005
2367 L lactate dehydrogenase B4 inhibitor60,005
2368 L lactate dehydrogenase C inhibitor160,002
2369 L lactate dehydrogenase C4 inhibitor160,002
2370 L lactate dehydrogenase inhibitor323,796
2371 L(+)-Tartrate dehydratase inhibitor70,045
2372 L-3-cyanoalanine synthase inhibitor100,422
2373 Laccase inhibitor184,557
2374 Lacrimal secretion stimulant729,137
2375 Lactaldehyde dehydrogenase inhibitor60,18
2376 Lactaldehyde reductase (NADPH) inhibitor40,858
2377 Lactaldehyde reductase inhibitor41,279
2378 Lactamase A inhibitor70,503
2379 Lactamase C inhibitor81,747
2380 Lactase inhibitor313,281
2381 Lactate 2-monooxygenase inhibitor137,044
2382 Lactate-malate transhydrogenase inhibitor50,455
2383 Lactose synthase inhibitor1411,223
2384 Lactosylceramide alpha-2,3-sialyltransferase inhibitor201,932
2385 Lactoylglutathione lyase inhibitor901,781
2386 Laminaribiose phosphorylase inhibitor92,443
2387 L-amino-acid oxidase inhibitor203,195
2388 L-aminoadipate-semialdehyde dehydrogenase inhibitor90,496
2389 Lanosterol 14 alpha demethylase inhibitor765,128
2390 Laryngospasm7515,329
2391 L-ascorbate peroxidase inhibitor161,39
2392 Lassitude treatment185,781
2393 Laxative506,485
2394 Lck kinase inhibitor9663,166
2395 LDLR expression enhancer1187,751
2396 LECT1 expression enhancer90
2397 Leishmanolysin inhibitor613,889
2398 Leucine dehydrogenase inhibitor58,277
2399 Leucine transaminase inhibitor50,674
2400 Leucine-tRNA ligase inhibitor306,405
2401 Leucolysin inhibitor61,738
2402 Leucyltransferase inhibitor141,245
2403 Leukocyte elastase inhibitor1843,129
2404 Leukopenia54218,005
2405 Leukopoiesis inhibitor2315,927
2406 Leukopoiesis stimulant916,963
2407 Leukotriene A4 hydrolase inhibitor3220,272
2408 Leukotriene agonist50,91
2409 Leukotriene antagonist13242,198
2410 Leukotriene B4 antagonist5881,77
2411 Leukotriene B4 receptor 1 antagonist4660,353
2412 Leukotriene B4 receptor 2 antagonist1970,062
2413 Leukotriene C antagonist2062,317
2414 Leukotriene C4 antagonist1951,303
2415 Leukotriene D4 antagonist5320,828
2416 Leukotriene E4 antagonist403,385
2417 Leukotriene synthesis inhibitor1923,512
2418 Leukotriene-B4 20-monooxygenase inhibitor54,411
2419 Leukotriene-C4 synthase inhibitor912,291
2420 Levanase inhibitor93,546
2421 Levansucrase inhibitor54,806
2422 LFA antagonist2610,286
2423 LFA-1 antagonist2610,286
2424 L-fuconate dehydratase inhibitor70,349
2425 L-galactonolactone oxidase inhibitor80,933
2426 L-glucuronate reductase inhibitor174,395
2427 L-glutamate oxidase inhibitor34,198
2428 Licheninase inhibitor62,111
2429 L-iditol 2-dehydrogenase inhibitor1002,431
2430 L-iduronidase inhibitor51,004
2431 Ligase inhibitor51,411
2432 Limulus clotting factor B inhibitor416,073
2433 Limulus clotting factor C inhibitor44,101
2434 Linoleate diol synthase inhibitor1511,084
2435 Linoleate isomerase inhibitor220,464
2436 Linoleoyl-CoA desaturase inhibitor64,213
2437 Lipase inhibitor1851,315
2438 Lipid metabolism regulator13112,295
2439 Lipid peroxidase inhibitor2828,959
2440 Lipocortins synthesis agonist753,596
2441 Lipocortins synthesis antagonist104,54
2442 Lipoprotein disorders treatment46014,656
2443 Lipoprotein lipase inhibitor1810,905
2444 Lipoprotein lipase stimulant2311,675
2445 Lipotropic112,298
2446 Lipoxin receptor agonist120,007
2447 Lipoxygenase inhibitor27492,895
2448 Lipoxygenase substrate255,704
2449 Liver cirrhosis treatment538,139
2450 Liver fibrosis treatment2667,047
2451 Liver X receptor agonist6230,675
2452 Liver X receptor alpha agonist2271,088
2453 Liver X receptor antagonist74,425
2454 Liver X receptor beta agonist3350,644
2455 L-lactate dehydrogenase (cytochrome) inhibitor60,187
2456 L-lysine 6-transaminase inhibitor60,898
2457 L-lysine oxidase inhibitor40,711
2458 Lombricine kinase inhibitor61,623
2459 Long-chain-acyl-CoA dehydrogenase inhibitor60,53
2460 Long-chain-aldehyde dehydrogenase inhibitor43,012
2461 Long-chain-fatty-acid-CoA ligase inhibitor230,707
2462 Loop diuretic813,141
2463 L-Serine ammonia-lyase inhibitor140,524
2464 L-threonine 3-dehydrogenase inhibitor1012,123
2465 Luteinizing hormone-releasing hormone agonist194,918
2466 Luteinizing hormone-releasing hormone antagonist9691,177
2467 Luteolytic40,028
2468 Lymphocytopoiesis inhibitor103,834
2469 Lysase inhibitor1016,567
2470 Lysine 2,3-aminomutase inhibitor511,123
2471 Lysine 2-monooxygenase inhibitor192,798
2472 Lysine 6-dehydrogenase inhibitor31,035
2473 Lysine carboxypeptidase inhibitor350,247
2474 Lysine decarboxylase inhibitor100,987
2475 Lysine-tRNA ligase inhibitor441,563
2476 Lysophosphatidic acid receptor agonist90,252
2477 Lysophosphatidic acid receptor antagonist780,715
2478 Lysosomal Pro-X carboxypeptidase inhibitor451,703
2479 Lysostaphin inhibitor32,992
2480 Lysozyme inhibitor131,441
2481 Lysyl endopeptidase inhibitor161,693
2482 Lysyl oxidase inhibitor1016,022
2483 M7G(5')pppN diphosphatase inhibitor40,022
2484 Macrocin O-methyltransferase inhibitor90,022
2485 Macrophage colony stimulating factor agonist417,987
2486 Macrophage colony stimulating factor antagonist1610,652
2487 Macrophage elastase inhibitor1822,093
2488 Macrophage migration inhibitory factor inhibitor832,062
2489 Macrophage scavenger receptor antagonist70,02
2490 Macrophage stimulant34,124
2491 Macular degeneration treatment2566,409
2492 Magnesium-protoporphyrin IX methyltransferase inhibitor112,045
2493 Magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase inhibitor103,464
2494 Magnolysin inhibitor60,094
2495 Maillard reaction inhibitor3510,613
2496 Malate dehydrogenase (acceptor) inhibitor1213,597
2497 Malate dehydrogenase (decarboxylating) inhibitor200,473
2498 Malate dehydrogenase (NADP+) inhibitor90,629
2499 Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) inhibitor210,477
2500 Malate dehydrogenase (oxaloacetate-decarboxylating) inhibitor161,41
2501 Malate dehydrogenase inhibitor666,493
2502 Malate oxidase inhibitor510,479
2503 Malate synthase inhibitor180,777
2504 Malate-CoA ligase inhibitor51,228
2505 Male reproductive disfunction treatment5656,213
2506 Maleate hydratase inhibitor110,449
2507 Maleate isomerase inhibitor64,596
2508 Maleylacetate reductase inhibitor40,01
2509 Maleylacetoacetate isomerase inhibitor60,385
2510 Malonate-semialdehyde dehydrogenase inhibitor30,487
2511 Malonyl-CoA decarboxylase inhibitor930,383
2512 Maltose-transporting ATPase inhibitor41,987
2513 Malyl-CoA lyase inhibitor61,531
2514 Mandelate 4-monooxygenase inhibitor114,019
2515 Mandelate racemase inhibitor270,43
2516 Manganese peroxidase inhibitor68,173
2517 Mannan endo-1,4-beta-mannosidase inhibitor35,454
2518 Mannan endo-1,6-alpha-mannosidase inhibitor40,874
2519 Mannitol 2-dehydrogenase inhibitor50,016
2520 Mannitol-1-phosphatase inhibitor31,382
2521 Mannitol-1-phosphate 5-dehydrogenase inhibitor180,899
2522 Mannokinase inhibitor90,056
2523 Mannonate dehydratase inhibitor90,842
2524 Mannose isomerase inhibitor58,116
2525 Mannose-1-phosphate guanylyltransferase inhibitor40,008
2526 Mannose-6-phosphate isomerase inhibitor1093,356
2527 Mannosidase inhibitor721,275
2528 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase inhibitor82,033
2529 Mannosyl-oligosaccharide 1,2-alpha-mannosidase inhibitor220,246
2530 Mannosyl-oligosaccharide glucosidase inhibitor180,304
2531 Mannotetraose 2-alpha-N-acetylglucosaminyltransferase inhibitor49,724
2532 MAO A inhibitor4631,845
2533 MAO A substrate252,556
2534 MAO B inhibitor6721,205
2535 MAO B substrate170,817
2536 MAO inhibitor11242,93
2537 MAP kinase 1 inhibitor1096,936
2538 MAP kinase 10 inhibitor2932,021
2539 MAP kinase 14 inhibitor15281,132
2540 MAP kinase 8 inhibitor2562,547
2541 MAP kinase 9 inhibitor3201,699
2542 MAP kinase inhibitor26982,465
2543 MAP kinase kinase 1 inhibitor2012,645
2544 MAP kinase kinase 4 inhibitor1811,146
2545 MAP kinase kinase 7 inhibitor113,997
2546 MAP kinase kinase inhibitor1801,002
2547 MAP kinase kinase kinase inhibitor1431,26
2548 MAP kinase stimulant712,835
2549 MAP3K11 inhibitor370,01
2550 MAP3K5 inhibitor89,963
2551 MAP3K8 inhibitor562,831
2552 MAP3K9 inhibitor260,135
2553 MAP-kinase-activated kinase 1 inhibitor163,362
2554 MAP-kinase-activated kinase 2 inhibitor1553,706
2555 MAP-kinase-activated kinase inhibitor1804,591
2556 MarA inhibitor120,001
2557 MARK1 protein inhibitor70,002
2558 Matrilysin inhibitor3310,692
2559 Matriptase inhibitor80,052
2560 Matrix metalloproteinase (membrane-type) inhibitor11240,911
2561 Matrix metalloproteinase 1 (membrane-type) inhibitor3540,868
2562 Matrix metalloproteinase 1 inhibitor15860,769
2563 Matrix metalloproteinase 2 (membrane-type) inhibitor180,331
2564 Matrix metalloproteinase 3 (membrane-type) inhibitor8780,749
2565 Matrix metalloproteinase inhibitor25801,144
2566 Mcl-1 antagonist9894,111
2567 MDM2 inhibitor1806,234
2568 Mediator release inhibitor14610,253
2569 Melanin inhibitor326,581
2570 Melanin-concentrating hormone receptor 1 antagonist10350,94
2571 Melanin-concentrating hormone receptor antagonist10390,935
2572 Melanocortin 4 antagonist3770,297
2573 Melanocortin agonist163,996
2574 Melanocortin antagonist5100,807
2575 Melanocortin MC-4 agonist101,7
2576 Melatonin 1 agonist270,405
2577 Melatonin 1 antagonist5600,313
2578 Melatonin 1a antagonist4040,264
2579 Melatonin 1b antagonist1270,586
2580 Melatonin 2 agonist150,04
2581 Melatonin 2 antagonist2330,089
2582 Melatonin 3 antagonist1000,122
2583 Melatonin 5 antagonist680,053
2584 Melatonin agonist980,25
2585 Melatonin antagonist7890,36
2586 Membrane dipeptidase inhibitor434,461
2587 Membrane integrity agonist1516,763
2588 Membrane integrity antagonist5613,33
2589 Membrane permeability enhancer4411,977
2590 Membrane permeability inhibitor4017,376
2591 Membrane-oligosaccharide glycerophosphotransferase inhibitor60,107
2592 Menopausal disorders treatment5313,359
2593 Menstruation disorders treatment2357,256
2594 Mental retardation treatment70,885
2595 Meprin A inhibitor132,529
2596 Meprin B inhibitor31,899
2597 Metabolic disease treatment1647,862
2598 Metallocarboxypeptidase D inhibitor74,223
2599 Metalloproteinase inhibitor29811,352
2600 Metalloproteinase-11 inhibitor311,816
2601 Metalloproteinase-2 inhibitor18121,28
2602 Metalloproteinase-3 inhibitor9510,763
2603 Metalloproteinase-9 inhibitor18371,053
2604 Methane monooxygenase inhibitor139,878
2605 Methanol dehydrogenase inhibitor31,597
2606 Methemoglobinemia164,487
2607 Methenyltetrahydrofolate cyclohydrolase inhibitor70,735
2608 Methionine adenosyltransferase inhibitor270,726
2609 Methionine decarboxylase inhibitor60,929
2610 Methionine-tRNA ligase inhibitor1390,72
2611 Methionyl aminopeptidase 1 inhibitor1860,215
2612 Methionyl aminopeptidase 2 inhibitor2300,527
2613 Methionyl aminopeptidase inhibitor4550,441
2614 Methionyl-tRNA formyltransferase inhibitor70,025
2615 Methylamine-glutamate N-methyltransferase inhibitor33,987
2616 Methylaspartate ammonia-lyase inhibitor81,62
2617 Methylaspartate mutase inhibitor80,085
2618 Methylcrotonoyl-CoA carboxylase inhibitor111,218
2619 Methylenetetrahydrofolate dehydrogenase (NADP+) inhibitor101,103
2620 Methylenetetrahydrofolate reductase (NADPH) inhibitor107,618
2621 Methylglutamate dehydrogenase inhibitor71,201
2622 Methylglyoxal synthase inhibitor150,178
2623 Methylmalonyl-CoA carboxytransferase inhibitor70,032
2624 Methylmalonyl-CoA decarboxylase inhibitor70,969
2625 Methylmalonyl-CoA epimerase inhibitor90,098
2626 Methylmalonyl-CoA mutase inhibitor110,877
2627 Methylthioadenosine nucleosidase inhibitor160,585
2628 Methyltransferase inhibitor50,035
2629 Methyltransferase substrate41,27
2630 Methylumbelliferyl-acetate deacetylase inhibitor712,688
2631 Mevalonate kinase inhibitor111,716
2632 MexAB-OprM inhibitor30
2633 Microbial collagenase inhibitor5140,535
2634 Microsomal triglyceride transfer protein inhibitor4230,084
2635 Microtubule formation inhibitor3206,034
2636 Microtubule stabilization1420,787
2637 Mineralocorticoid160,021
2638 Mineralocorticoid antagonist4410,997
2639 Miotic12210,499
2640 Mitochondrial intermediate peptidase inhibitor62,134
2641 Mitochondrial processing peptidase inhibitor617,35
2642 MMP9 expression inhibitor1612,358
2643 MO15-related protein kinase Pfmrk inhibitor187,697
2644 Monoamine oxidase substrate451,675
2645 Monoamine uptake inhibitor418,414
2646 Monocarboxylic acid transporter 1 inhibitor62,665
2647 Monocarboxylic acid transporter inhibitor62,665
2648 Monodehydroascorbate reductase (NADH) inhibitor178,033
2649 Monophenol monooxygenase inhibitor1133,628
2650 Mood disorders treatment83038,192
2651 Morphine 6-dehydrogenase inhibitor134,184
2652 Motilin receptor agonist1010,795
2653 Motilin receptor antagonist780,011
2654 Movement disorders treatment436,116
2655 mRNA (guanine-N7-)-methyltransferase inhibitor183,451
2656 mRNA (nucleoside-2'-O-)-methyltransferase inhibitor160,003
2657 mTOR inhibitor6430,587
2658 Mucinaminylserine mucinaminidase inhibitor516,984
2659 Mucolytic1047,897
2660 Mucomembranous protector3319,548
2661 Muconate cycloisomerase inhibitor40,242
2662 Mucorpepsin inhibitor53,51
2663 Mucositis treatment1416,022
2664 Multidrug resistance-associated protein 1 inhibitor2233,327
2665 Multidrug resistance-associated protein inhibitor2243,766
2666 Multiple inositol-polyphosphate phosphatase inhibitor50,021
2667 Multiple organ failure311,52
2668 Multiple sclerosis treatment95910,857
2669 Muramoyltetrapeptide carboxypeptidase inhibitor56,661
2670 Muscle relaxant3957,826
2671 Muscle weakness19115,179
2672 Muscular dystrophy treatment6213,396
2673 Mutagenic35422,87
2674 Mutagenic, Salmonella33022,603
2675 Myc inhibitor913,013
2676 Mycodextranase inhibitor60,553
2677 Mycolysin inhibitor30,257
2678 Mycothiol-S-conjugate amidase inhibitor310,712
2679 Mydriatic2119,577
2680 Myelin associated glycoprotein antagonist40
2681 Myeloblastin inhibitor41,693
2682 Myocardial infarction treatment6004,959
2683 Myocardial ischemia treatment16644,891
2684 Myocarditis2517,641
2685 Myoclonus7915,798
2686 Myosin ATPase inhibitor1112,696
2687 Myosin-light-chain-phosphatase inhibitor62,428
2688 Myristoyl transferase 1 inhibitor730,278
2689 Myristoyl transferase inhibitor930,253
2690 Myt1 kinase inhibitor70,004
2691 N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase inhibitor81,629
2692 N-(long-chain-acyl)ethanolamine deacylase inhibitor72,624
2693 N4-(beta-N-acetylglucosaminyl)-L-asparaginase inhibitor101,556
2694 N6-methyl-lysine oxidase inhibitor41,571
2695 Na+ K+ transporting ATPase inhibitor1651,458
2696 Na+-transporting two-sector ATPase inhibitor717,108
2697 N-Acetylated alpha-linked acidic dipeptidase inhibitor1580,143
2698 N-acetylgalactosamine-4-sulfatase inhibitor30,005
2699 N-acetyl-gamma-glutamyl-phosphate reductase inhibitor31,069
2700 N-acetylglucosamine kinase inhibitor150,713
2701 N-acetylglucosamine-6-phosphate deacetylase inhibitor100,625
2702 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase inhibitor60,222
2703 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase inhibitor35,966
2704 N-acetyllactosamine synthase inhibitor63,305
2705 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase inhibitor52,93
2706 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase inhibitor70,304
2707 N-acetylmuramoyl-L-alanine amidase inhibitor110,296
2708 N-acetylneuraminate 4-O-acetyltransferase inhibitor32,152
2709 N-acetylneuraminate 7-O(or 9-O)-acetyltransferase inhibitor618,732
2710 N-acetylneuraminate lyase inhibitor140,742
2711 N-acetylneuraminate synthase inhibitor40,887
2712 N-Acyl-D-amino-acid deacylase inhibitor41,105
2713 N-Acyl-D-aspartate deacylase inhibitor31,495
2714 N-acylmannosamine kinase inhibitor511,665
2715 N-acylneuraminate cytidylyltransferase inhibitor150,698
2716 NAD(P)+ transhydrogenase (AB-specific) inhibitor312,163
2717 NAD(P)+ transhydrogenase (B-specific) inhibitor113,697
2718 NAD(P)+-arginine ADP-ribosyltransferase inhibitor1113,801
2719 NAD(P)H dehydrogenase (quinone) 1 inhibitor500,141
2720 NAD(P)H dehydrogenase (quinone) inhibitor1471,957
2721 NAD+ diphosphatase inhibitor110,803
2722 NAD+ kinase inhibitor173,663
2723 NAD+ nucleosidase inhibitor190,634
2724 NAD+ synthase (glutamine-hydrolysing) inhibitor41,685
2725 NAD+-dinitrogen-reductase ADP-D-ribosyltransferase inhibitor30,664
2726 NADH dehydrogenase inhibitor174,458
2727 NADH kinase inhibitor32,457
2728 NADH oxidase inhibitor180,01
2729 NADPH oxidase inhibitor763,215
2730 NADPH oxidoreductase inhibitor201,062
2731 NADPH peroxidase inhibitor49,113
2732 NADPH-cytochrome-c2 reductase inhibitor312,152
2733 NADPH-ferrihemoprotein reductase inhibitor1013,166
2734 Nail discoloration416,145
2735 Naphthalene 1,2-dioxygenase inhibitor33,263
2736 Narcolepsy treatment123,736
2737 Narcotic antagonist713,236
2738 Nardilysin inhibitor86,633
2739 NAT1 substrate200,518
2740 NAT2 substrate351,259
2741 Nausea104218,142
2742 Nav1.1 sodium channel blocker1643,922
2743 Nav1.2 sodium channel blocker2224,058
2744 Nav1.3 sodium channel blocker1603,973
2745 Nav1.4 sodium channel blocker231,152
2746 Nav1.5 sodium channel blocker916,874
2747 Nav1.7 sodium channel blocker973,445
2748 Nav1.8 sodium channel blocker1904,027
2749 N-benzyloxycarbonylglycine hydrolase inhibitor611,94
2750 N-Carbamoyl-D-amino acid hydrolase inhibitor51,373
2751 N-carbamoyl-L-amino-acid hydrolase inhibitor101,672
2752 Necroptosis inhibitor65,758
2753 Necrosis18319,623
2754 Necrosis treatment60
2755 Neolactotetraosylceramide alpha-2,3-sialyltransferase inhibitor60,668
2756 Nephritis12418,359
2757 Nephrotic syndrome5619,114
2758 Nephrotoxic78715,977
2759 Nerve growth factor antagonist400,718
2760 Neuraminidase (Influenza A) inhibitor1660,006
2761 Neuraminidase (Influenza B) inhibitor650,024
2762 Neuraminidase (influenza) inhibitor1950,232
2763 Neuraminidase inhibitor3091,249
2764 Neurodegenerative diseases treatment557114,024
2765 Neurokinin 1 antagonist14330,428
2766 Neurokinin 2 antagonist7080,97
2767 Neurokinin 3 antagonist3440,819
2768 Neurokinin antagonist20570,739
2769 Neuroleptic malignant syndrome519,932
2770 Neurolysin inhibitor251,408
2771 Neuronal nicotinic receptor antagonist7390,589
2772 Neuronal nitric-oxide synthase inhibitor4370,34
2773 Neuropathy treatment210,08
2774 Neuropeptide agonist168,997
2775 Neuropeptide antagonist14443,131
2776 Neuropeptide FF agonist812,082
2777 Neuropeptide FF antagonist660,213
2778 Neuropeptide FF1 antagonist300,278
2779 Neuropeptide FF2 agonist812,082
2780 Neuropeptide S antagonist410,726
2781 Neuropeptide Y agonist74,23
2782 Neuropeptide Y antagonist13743,214
2783 Neuropeptide Y1 agonist60
2784 Neuropeptide Y1 antagonist3894,609
2785 Neuropeptide Y2 antagonist11712,481
2786 Neuropeptide Y4 antagonist619,715
2787 Neuropeptide Y5 antagonist8370,766
2788 Neuropsin inhibitor51,094
2789 Neurotensin 1 receptor agonist30,191
2790 Neurotensin 1 receptor antagonist532,598
2791 Neurotensin 2 receptor antagonist270,001
2792 Neurotensin 3 receptor antagonist250,001
2793 Neurotensin receptor agonist160,162
2794 Neurotensin receptor antagonist1130,641
2795 Neurotoxic63814,249
2796 Neurotransmitter antagonist916,889
2797 Neurotransmitter uptake inhibitor310,13
2798 Neurotrophic factor4683,877
2799 Neurotrophic factor enhancer747,037
2800 Neutral endopeptidase inhibitor6980,47
2801 Neutropenia treatment540,034
2802 Neutrophil collagenase inhibitor7461,177
2803 Neutrophil fMLF receptor antagonist230
2804 Neutrophilic dermatosis (Sweet's syndrome)416,035
2805 NF-E2-related factor 2 stimulant105,073
2806 N-formylglutamate deformylase inhibitor160,539
2807 N-formylmethionyl-peptidase inhibitor33,086
2808 N-hydroxy-2-acetamidofluorene reductase inhibitor31,906
2809 N-hydroxyarylamine O-acetyltransferase inhibitor1115,907
2810 Nicotinamidase inhibitor241,609
2811 Nicotinamide phosphoribosyltransferase inhibitor133,327
2812 Nicotinamide-nucleotide adenylyltransferase inhibitor70,839
2813 Nicotinamide-nucleotide amidase inhibitor60,005
2814 Nicotinate dehydrogenase inhibitor614,581
2815 Nicotinate phosphoribosyltransferase inhibitor170,483
2816 Nicotinate-nucleotide diphosphorylase (carboxylating) inhibitor320,595
2817 Nicotine dehydrogenase inhibitor518,478
2818 Nicotinic acid receptor 1 agonist1021,278
2819 Nicotinic acid receptor 2 agonist260,378
2820 Nicotinic acid receptor agonist2010,707
2821 Nicotinic alpha2beta2 receptor antagonist411,148
2822 Nicotinic alpha2beta4 receptor agonist413,798
2823 Nicotinic alpha3beta4 receptor agonist120,885
2824 Nicotinic alpha4 receptor agonist160,023
2825 Nicotinic alpha4beta2 receptor agonist340,14
2826 Nicotinic alpha4beta2 receptor antagonist185,705
2827 Nicotinic alpha4beta4 receptor agonist39,977
2828 Nicotinic alpha6 receptor agonist30,36
2829 Nicotinic alpha6beta3beta4alpha5 receptor antagonist315,304
2830 Nicotinic alpha7 receptor agonist5350,616
2831 Nicotinic neuronal receptor agonist6110,923
2832 Nicotinic receptor alpha7 subunit antagonist590,872
2833 Niemann-Pick C1-like 1 protein antagonist238,035
2834 Nitrate reductase (cytochrome) inhibitor1113,018
2835 Nitrate reductase inhibitor306,121
2836 Nitric oxide antagonist1465,448
2837 Nitric oxide donor1970,614
2838 Nitric oxide scavenger45,63
2839 Nitric-oxide synthase inhibitor10752,242
2840 Nitric-oxide synthase stimulant199,283
2841 Nitrilase inhibitor181,683
2842 Nitrile hydratase inhibitor221,26
2843 Nitrite reductase (NO-forming) inhibitor34,574
2844 Nitrite reductase [NAD(P)H] inhibitor1812,289
2845 NMDA 2 receptor antagonist9411,017
2846 NMDA 2A receptor antagonist5680,534
2847 NMDA 2B receptor antagonist3961,008
2848 NMDA receptor agonist1641,892
2849 NMDA receptor antagonist40212,007
2850 NMDA receptor glutamate site antagonist410,14
2851 NMDA receptor glycine site agonist1271,149
2852 NMDA receptor glycine site antagonist5860,249
2853 NMDA receptor glycine site B antagonist50,084
2854 NMDA receptor phencyclidine site antagonist1520,14
2855 NMDA receptor polyamine site agonist30,055
2856 NMDA receptor polyamine site antagonist55,836
2857 N-methyl-2-oxoglutaramate hydrolase inhibitor92,857
2858 N-methylhydantoinase (ATP-hydrolysing) inhibitor53,149
2859 NMN nucleosidase inhibitor160,724
2860 Nociceptin (N/OFQ) receptor agonist80,008
2861 Nociceptin (N/OFQ) receptor antagonist3200,39
2862 Non mutagenic, Salmonella4507,91
2863 Non-steroidal antiinflammatory agent10758,38
2864 Nootropic112824,036
2865 NOS2 expression inhibitor436,507
2866 NOS3 expression enhancer734,304
2867 NTPase/helicase (JEV) inhibitor30,024
2868 NTPase/helicase (WNF) inhibitor90,006
2869 Nuclear receptor subfamily 4, group A, member 2 agonist240,232
2870 Nuclease inhibitor143,854
2871 Nucleoside deoxyribosyltransferase inhibitor80,211
2872 Nucleoside oxidase (H2O2-forming) inhibitor63,243
2873 Nucleoside phosphoacylhydrolase inhibitor41,217
2874 Nucleoside transporters inhibitor180,12
2875 Nucleoside-diphosphatase inhibitor102,979
2876 Nucleoside-triphosphate diphosphatase inhibitor70,007
2877 Nucleoside-triphosphate-adenylate kinase inhibitor71,439
2878 Nucleotidase inhibitor65,531
2879 Nucleotide diphosphatase inhibitor372,06
2880 Nucleotide metabolism regulator13813,25
2881 Nucleotidyltransferase (FIV) inhibitor150,392
2882 Nucleotidyltransferase inhibitor180,194
2883 O6-alkylguanine-DNA alkyltransferase inhibitor1300,544
2884 O-acetylhomoserine aminocarboxypropyltransferase inhibitor152,107
2885 O-aminophenol oxidase inhibitor128,631
2886 Obsessive-compulsive disorder treatment685,274
2887 Occult bleeding310,398
2888 Octadecanal decarbonylase inhibitor60,584
2889 Octopamine agonist670,062
2890 Octopamine antagonist519,921
2891 Ocular toxicity63917,893
2892 Oleamide hydrolase inhibitor3080,913
2893 Oligo-1,6-glucosidase inhibitor241
2894 Oligonucleotidase inhibitor100,592
2895 Oligopeptidase B inhibitor72,841
2896 Omega-amidase inhibitor80,959
2897 Omptin inhibitor411,867
2898 Opheline kinase inhibitor32,057
2899 Ophthalmic drug189210,537
2900 Opine dehydrogenase inhibitor42,157
2901 Opioid delta 1 receptor antagonist114,511
2902 Opioid delta 2 receptor antagonist120,045
2903 Opioid dependency treatment3612,427
2904 Opioid kappa 1 receptor antagonist900,846
2905 Opioid kappa 2 receptor antagonist140,001
2906 Opioid kappa 2b receptor antagonist140,001
2907 Opioid kappa 3 receptor antagonist1015,043
2908 Opioid mu 1 receptor antagonist212,073
2909 Opioid mu 2 receptor antagonist241,465
2910 Optic neuritis6021,875
2911 Optic neuropathy6822,415
2912 Orcinol 2-monooxygenase inhibitor70,091
2913 Orexin receptor 1 antagonist4753,989
2914 Orexin receptor 2 antagonist2440,121
2915 Orexin receptor antagonist7423,303
2916 Ornithine carbamoyltransferase inhibitor400,991
2917 Ornithine cyclodeaminase inhibitor31,194
2918 Ornithine decarboxylase inhibitor1021,963
2919 Ornithine-oxo-acid transaminase inhibitor393,977
2920 Orotate phosphoribosyltransferase inhibitor360,526
2921 Orotate reductase (NADH) inhibitor81,328
2922 Orotate reductase (NADPH) inhibitor50,26
2923 Orotidylate decarboxylase inhibitor40,094
2924 Orsellinate decarboxylase inhibitor50,004
2925 Oryzin inhibitor108,214
2926 Osmotic diuretic60,151
2927 Osteoarthritis treatment2795,003
2928 Osteoclast antagonist811,779
2929 Ototoxicity4312,628
2930 Ovulation inhibitor1514,249
2931 Oxalate oxidase inhibitor135,228
2932 Oxaloacetate decarboxylase inhibitor150,734
2933 Oxaloacetate tautomerase inhibitor150,398
2934 Oxidizing agent164,576
2935 Oxidoreductase inhibitor8215,567
2936 Oxoglutarate dehydrogenase (lipoamide) inhibitor171,139
2937 Oxygen scavenger915,54
2938 Oxytocic209,502
2939 Oxytocin agonist164,365
2940 Oxytocin antagonist7930,934
2941 P2 nucleoside transporter inhibitor110
2942 p21-activated kinase 1 inhibitor912,371
2943 p21-activated kinase 4 inhibitor204,899
2944 p21-activated kinase inhibitor227,52
2945 P3 purinoceptor-like protein antagonist350,006
2946 p38 MAP kinase inhibitor4232,308
2947 p53 inhibitor273,571
2948 Paget's disease treatment432,093
2949 Pain97018,242
2950 Palmitoyl-CoA hydrolase inhibitor442,13
2951 Palpitation3115,255
2952 Pancreatic disorders treatment1489,283
2953 Pancreatic elastase inhibitor1019,915
2954 Pancreatic endopeptidase E inhibitor61,04
2955 Pancreatic ribonuclease inhibitor108,563
2956 Panic139,094
2957 Pantetheine-phosphate adenylyltransferase inhibitor163,344
2958 Pantoate 4-dehydrogenase inhibitor30,62
2959 Pantoate-beta-alanine ligase inhibitor392,642
2960 Pantothenase inhibitor101,132
2961 Pantothenate kinase inhibitor180,125
2962 Papillary necrosis40,32
2963 Pappalysin-1 inhibitor42,981
2964 Para amino benzoic acid antagonist811,766
2965 Paralysis13419,954
2966 Paraoxonase substrate51,297
2967 Parathyroid hormone antagonist191,459
2968 Parathyroid hormone secretion stimulant710,186
2969 Parkinsonism2713,726
2970 P-benzoquinone reductase (NADPH) inhibitor815,091
2971 Pectate lyase inhibitor111,899
2972 Pectin lyase inhibitor111,297
2973 Pediculicide103,534
2974 Penicillin amidase inhibitor104,207
2975 Penicillopepsin inhibitor142,868
2976 Pepsin inhibitor800,53
2977 Peptide agonist35,292
2978 Peptide alpha-N-acetyltransferase inhibitor66,457
2979 Peptide deformylase inhibitor1810,917
2980 Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase inhibitor69,472
2981 Peptide-tryptophan 2,3-dioxygenase inhibitor91,716
2982 Peptidoglycan beta-N-acetylmuramidase inhibitor30,608
2983 Peptidoglycan glycosyltransferase inhibitor48,215
2984 Peptidylamidoglycolate lyase inhibitor51,132
2985 Peptidyl-dipeptidase B inhibitor714,534
2986 Peptidyl-dipeptidase Dcp inhibitor65,825
2987 Peptidyl-glycinamidase inhibitor112,441
2988 Peptidylglycine monooxygenase inhibitor381,36
2989 Peptidyl-Lys metalloendopeptidase inhibitor224,974
2990 Peptidyl-prolyl cis-trans isomerase inhibitor3880,717
2991 Peptidyltransferase inhibitor2010,364
2992 Periodontitis treatment202,765
2993 Peristaltic stimulant1745,284
2994 Peroxidase inhibitor166,867
2995 Peroxidase substrate338,175
2996 Peroxisome proliferator-activated receptor agonist19581,169
2997 Peroxisome proliferator-activated receptor alpha agonist10050,806
2998 Peroxisome proliferator-activated receptor alpha antagonist3830,439
2999 Peroxisome proliferator-activated receptor antagonist9662,176
3000 Peroxisome proliferator-activated receptor delta agonist4090,373
3001 Peroxisome proliferator-activated receptor delta antagonist2600,361
3002 Peroxisome proliferator-activated receptor gamma agonist9351,388
3003 Peroxisome proliferator-activated receptor gamma antagonist8102,431
3004 PfA-M1 aminopeptidase inhibitor557,686
3005 pFOX inhibitor50,035
3006 P-glycoprotein 1 inhibitor4506,412
3007 P-glycoprotein inhibitor6446,599
3008 P-glycoprotein substrate5914,94
3009 Phenol 2-monooxygenase inhibitor254,017
3010 Phenol O-methyltransferase inhibitor34,633
3011 Phenylacetaldehyde dehydrogenase inhibitor51,134
3012 Phenylacetate-CoA ligase inhibitor82,178
3013 Phenylalanine 2-monooxygenase inhibitor60,081
3014 Phenylalanine 4-hydroxylase inhibitor302,115
3015 Phenylalanine decarboxylase inhibitor81,73
3016 Phenylalanine dehydrogenase inhibitor191,283
3017 Phenylalanine racemase (ATP-hydrolysing) inhibitor102,132
3018 Phenylalanine(histidine) transaminase inhibitor41,775
3019 Phenylalanine-tRNA ligase inhibitor221,045
3020 Phenylethanolamine N methyltransferase inhibitor880,207
3021 Phenylpyruvate decarboxylase inhibitor30,625
3022 Phenylpyruvate tautomerase inhibitor50,001
3023 Phloroglucinol reductase inhibitor138,322
3024 Phobic disorders treatment418,387
3025 Phosphatase inhibitor919,827
3026 Phosphate acetyltransferase inhibitor141,545
3027 Phosphate butyryltransferase inhibitor40,002
3028 Phosphate transporter inhibitor261,874
3029 Phosphatidate cytidylyltransferase inhibitor171,695
3030 Phosphatidate phosphatase inhibitor245,315
3031 Phosphatidylcholine-retinol O-acyltransferase inhibitor417,536
3032 Phosphatidylcholine-sterol O-acyltransferase inhibitor1610,274
3033 Phosphatidylglycerol-membrane-oligosaccharide glycerophosphotransferase inhibitor30,385
3034 Phosphatidylglycerophosphatase inhibitor82,845
3035 Phosphatidylinositol 3-kinase alpha inhibitor6221,11
3036 Phosphatidylinositol 3-kinase beta inhibitor3030,987
3037 Phosphatidylinositol 3-kinase delta inhibitor2901,109
3038 Phosphatidylinositol 3-kinase gamma inhibitor5200,616
3039 Phosphatidylinositol 3-kinase inhibitor12011,368
3040 Phosphatidylinositol 3-kinase stimulant617,916
3041 Phosphatidylinositol diacylglycerol-lyase inhibitor127,436
3042 Phosphatidylinositol kinase inhibitor12351,406
3043 Phosphatidylserine decarboxylase inhibitor106,572
3044 Phosphoadenylylsulfatase inhibitor50,215
3045 Phosphodiesterase 10A inhibitor1060,879
3046 Phosphodiesterase 11A inhibitor680,566
3047 Phosphodiesterase 1B inhibitor2232,236
3048 Phosphodiesterase 3A inhibitor2571,647
3049 Phosphodiesterase 4A inhibitor7441,391
3050 Phosphodiesterase 4B inhibitor10501,248
3051 Phosphodiesterase 4C inhibitor9251,113
3052 Phosphodiesterase 4D inhibitor10531,185
3053 Phosphodiesterase 5A inhibitor4691,711
3054 Phosphodiesterase 6A inhibitor1760,134
3055 Phosphodiesterase 6B inhibitor1060,214
3056 Phosphodiesterase 7A inhibitor551,349
3057 Phosphodiesterase 9A inhibitor320,046
3058 Phosphodiesterase I inhibitor4033,441
3059 Phosphodiesterase II inhibitor1202,596
3060 Phosphodiesterase III inhibitor11271,367
3061 Phosphodiesterase inhibitor59052,908
3062 Phosphodiesterase IV inhibitor34181,315
3063 Phosphodiesterase IX inhibitor350,02
3064 Phosphodiesterase V inhibitor10291,557
3065 Phosphodiesterase VI inhibitor2600,292
3066 Phosphodiesterase VII inhibitor1671,631
3067 Phosphodiesterase X inhibitor1060,879
3068 Phosphodiesterase XI inhibitor680,566
3069 Phosphoenolpyruvate carboxykinase (ATP) inhibitor345,438
3070 Phosphoenolpyruvate carboxykinase (diphosphate) inhibitor80,533
3071 Phosphoenolpyruvate carboxykinase (GTP) inhibitor250,301
3072 Phosphoenolpyruvate carboxylase inhibitor731,082
3073 Phosphoenolpyruvate mutase inhibitor31,345
3074 Phosphoenolpyruvate-protein phosphotransferase inhibitor40,992
3075 Phosphofructokinase-1 inhibitor331,526
3076 Phosphoglucomutase inhibitor160,529
3077 Phosphogluconate 2-dehydrogenase inhibitor140,108
3078 Phosphogluconate dehydrogenase (decarboxylating) inhibitor560,991
3079 Phosphoglycerate dehydrogenase inhibitor160,398
3080 Phosphoglycerate kinase inhibitor1890,44
3081 Phosphoglycerate mutase inhibitor100,902
3082 Phosphoglycerate phosphatase inhibitor60,048
3083 Phosphoglycolate phosphatase inhibitor120,724
3084 Phosphoinositide 5-phosphatase inhibitor119,421
3085 Phosphoinositide dependent kinase 1 inhibitor391,865
3086 Phosphoinositide phospholipase C inhibitor96,142
3087 Phosphoketolase inhibitor100,264
3088 Phospholipase A1 inhibitor165,509
3089 Phospholipase A2 IIa inhibitor1270,95
3090 Phospholipase A2 inhibitor5413,515
3091 Phospholipase C inhibitor517,178
3092 Phospholipase D inhibitor1073,14
3093 Phospholipase D1 inhibitor413,941
3094 Phospholipase D2 inhibitor861,284
3095 Phospholipase inhibitor6873,964
3096 Phospholipid-translocating ATPase inhibitor412,386
3097 Phosphomannomutase inhibitor170,21
3098 Phosphomevalonate kinase inhibitor140,763
3099 Phospho-N-acetylmuramoyl-pentapeptide-transferase inhibitor1270,327
3100 Phosphonoacetate hydrolase inhibitor60,806
3101 Phosphopantothenoylcysteine decarboxylase inhibitor75,893
3102 Phosphopyruvate hydratase inhibitor70,027
3103 Phosphoribosylformylglycinamidine cyclo-ligase inhibitor30,012
3104 Phosphoribosylformylglycinamidine synthase inhibitor70,202
3105 Phosphoribosylglycinamide formyltransferase inhibitor1210,017
3106 Phosphoribulokinase inhibitor100,691
3107 Phosphorylase a inhibitor260,925
3108 Phosphorylase b inhibitor53,63
3109 Phosphorylase inhibitor2791,466
3110 Phosphorylase kinase inhibitor572,789
3111 Phosphoserine phosphatase inhibitor101,131
3112 Phosphoserine transaminase inhibitor50,094
3113 Photinus-luciferin 4-monooxygenase (ATP-hydrolysing) inhibitor434,772
3114 Photoallergy dermatitis5815,546
3115 Photosensitizer295,601
3116 Phthalate 4,5-dioxygenase inhibitor312,865
3117 Phytanoyl-CoA dioxygenase inhibitor32,145
3118 Picornain 2A inhibitor101,914
3119 Picornain 3C inhibitor82,214
3120 Piloerection1312,56
3121 Pim kinase inhibitor1503,568
3122 Pim-1 kinase inhibitor915,273
3123 Pim-2 kinase inhibitor604,616
3124 Pim-3 kinase inhibitor195,074
3125 Pin1 inhibitor511,116
3126 Pitrilysin inhibitor105,91
3127 Plasmanylethanolamine desaturase inhibitor81,962
3128 Plasmepsin I inhibitor630,029
3129 Plasmepsin II inhibitor992,591
3130 Plasmepsin inhibitor1082,451
3131 Plasmin inhibitor3231,241
3132 Plasminogen activator inhibitor1341,427
3133 Plasminogen activator inhibitor antagonist1651,567
3134 Plasminogen activator stimulant142,814
3135 Plastoquinol-plastocyanin reductase inhibitor76,089
3136 Platelet activating factor alpha antagonist6051,674
3137 Platelet activating factor antagonist24312,848
3138 Platelet activating factor beta antagonist9211,861
3139 Platelet adhesion inhibitor1717,621
3140 Platelet aggregation inhibitor38268,996
3141 Platelet aggregation stimulant715,249
3142 Platelet antagonist19284,832
3143 Platelet derived growth factor receptor kinase inhibitor1313,566
3144 Platelet growth factor antagonist7561,341
3145 Platelet growth factor beta antagonist1860,72
3146 Plus-end-directed kinesin ATPase inhibitor31,326
3147 Pneumotoxic174,491
3148 Polar-amino-acid-transporting ATPase inhibitor43,38
3149 Polarisation inhibitor416,38
3150 Polarisation stimulant99,161
3151 Polo-like kinase inhibitor2952,417
3152 Polo-like kinase-1 inhibitor2142,283
3153 Poly(3-hydroxybutyrate) depolymerase inhibitor131,233
3154 Poly(ADP-ribose) glycohydrolase inhibitor192,517
3155 Poly(ADP-ribose) polymerase 1 inhibitor6220,502
3156 Poly(ADP-ribose) polymerase 2 inhibitor531,129
3157 Poly(ADP-ribose) polymerase inhibitor12411,063
3158 Poly(alpha-L-guluronate) lyase inhibitor52,066
3159 Poly(beta-D-mannuronate) lyase inhibitor43,206
3160 Polyamine biosynthesis inhibitor180,873
3161 Polyamine oxidase inhibitor144,324
3162 Polyamine-transporting ATPase inhibitor34,698
3163 Polygalacturonase inhibitor63,275
3164 Polyneuridine-aldehyde esterase inhibitor31,242
3165 Polynucleotide 5'-hydroxy-kinase inhibitor158,064
3166 Polynucleotide adenylyltransferase inhibitor275,275
3167 Polypeptide N-acetylgalactosaminyltransferase inhibitor161,165
3168 Polyphosphate kinase inhibitor40,469
3169 Polyphosphate-glucose phosphotransferase inhibitor50,039
3170 Polyporopepsin inhibitor616,583
3171 Polyribonucleotide nucleotidyltransferase inhibitor99,46
3172 Porphobilinogen synthase inhibitor221,45
3173 Porphyria2812,732
3174 Postcoital contraceptive420,952
3175 Postmenopausal disorders treatment2421,849
3176 Postsynaptic density protein 95 inhibitor30
3177 Posttraumatic stress disorder treatment305,574
3178 Postural (orthostatic) hypotension2712,103
3179 Potassium channel (ATP-sensitive) activator1722,029
3180 Potassium channel (ATP-sensitive) blocker2391,156
3181 Potassium channel (Ca-activated) activator1862,84
3182 Potassium channel (Ca-activated) blocker2611,653
3183 Potassium channel (Inward rectifier) 1 blocker800,175
3184 Potassium channel (Inward rectifier) 11 blocker860,633
3185 Potassium channel (Inward rectifier) activator1722,029
3186 Potassium channel (Inward rectifier) blocker3941,03
3187 Potassium channel (Voltage-sensitive) activator1620,838
3188 Potassium channel (Voltage-sensitive) blocker21024,505
3189 Potassium channel activator14301,912
3190 Potassium channel blocker31315,018
3191 Potassium channel intermediate-conductance Ca-activated 4 blocker340,004
3192 Potassium channel intermediate-conductance Ca-activated activator41,308
3193 Potassium channel intermediate-conductance Ca-activated blocker661,091
3194 Potassium channel KCNQ activator1620,838
3195 Potassium channel KCNQ blocker80,273
3196 Potassium channel KCNQ2 activator450,02
3197 Potassium channel KCNQ3 activator61,705
3198 Potassium channel Kv1.1 blocker1351,738
3199 Potassium channel Kv1.3 blocker2451,058
3200 Potassium channel Kv1.5 blocker4441,71
3201 Potassium channel Kv4.3 blocker822,146
3202 Potassium channel large-conductance Ca-activated activator1611,92
3203 Potassium channel small-conductance Ca-activated 3 activator61,005
3204 Potassium channel small-conductance Ca-activated 3 blocker420,033
3205 Potassium channel small-conductance Ca-activated activator90,103
3206 Potassium channel small-conductance Ca-activated blocker1250,337
3207 Pregnane X receptor agonist135,291
3208 Pregnane X receptor antagonist351,273
3209 Premature ejaculation treatment1122,055
3210 Premenstrual syndrome treatment264,334
3211 Preneoplastic conditions treatment813,571
3212 Prenyl-diphosphatase inhibitor52,529
3213 Prephenate dehydratase inhibitor230,623
3214 Prephenate dehydrogenase inhibitor204,986
3215 Prepilin peptidase inhibitor30,524
3216 Preterm labor treatment872,532
3217 Prion diseases treatment3116,914
3218 PRL phosphatase inhibitor283,912
3219 Procollagen C-endopeptidase inhibitor173,419
3220 Procollagen galactosyltransferase inhibitor130,265
3221 Procollagen glucosyltransferase inhibitor130,581
3222 Procollagen N-endopeptidase inhibitor72,714
3223 Procollagen-lysine 5-dioxygenase inhibitor213,71
3224 Procollagen-proline 3-dioxygenase inhibitor140,007
3225 Progesterone agonist1730,748
3226 Progesterone antagonist10880,385
3227 Progesterone receptor A antagonist980,028
3228 Progesterone receptor B antagonist660,099
3229 Progesterone receptor B1 antagonist240,012
3230 Prokinetic5122,023
3231 Prokineticin receptor 1 antagonist30
3232 Prolactin inhibitor433,197
3233 Prolactin release inhibitor631,221
3234 Proliferative diseases treatment2078,59
3235 Proline dehydrogenase inhibitor40,195
3236 Proline racemase inhibitor170,578
3237 Proline transporter inhibitor230
3238 Prolyl aminopeptidase inhibitor136,242
3239 Prolyl endopeptidase inhibitor3541,348
3240 Pro-opiomelanocortin converting enzyme inhibitor55,979
3241 Propanediol dehydratase inhibitor170,604
3242 Propionate CoA-transferase inhibitor40,081
3243 Propionate-CoA ligase inhibitor70,602
3244 Prostacyclin agonist621,556
3245 Prostacyclin antagonist1380,521
3246 Prostaglandin A1 agonist30
3247 Prostaglandin agonist3240,998
3248 Prostaglandin antagonist17391,301
3249 Prostaglandin D2 agonist92,306
3250 Prostaglandin D2 antagonist5640,219
3251 Prostaglandin E1 agonist200,05
3252 Prostaglandin E1 antagonist44,45
3253 Prostaglandin E2 agonist1200,366
3254 Prostaglandin E2 antagonist7171,308
3255 Prostaglandin EP1 antagonist1270,217
3256 Prostaglandin EP12 antagonist500,044
3257 Prostaglandin EP2 agonist380,039
3258 Prostaglandin EP2 antagonist1730,165
3259 Prostaglandin EP3 antagonist4710,245
3260 Prostaglandin EP4 agonist700,005
3261 Prostaglandin EP4 antagonist2900,168
3262 Prostaglandin F2 alpha agonist260,03
3263 Prostaglandin F2 alpha antagonist481,888
3264 Prostaglandin H2 antagonist3790,186
3265 Prostaglandin-A1 DELTA-isomerase inhibitor47,488
3266 Prostaglandin-E synthase inhibitor1580,291
3267 Prostaglandin-E2 9-reductase inhibitor1510,776
3268 Prostaglandin-E2 synthase 1 inhibitor320,434
3269 Prostaglandin-I synthase inhibitor421,136
3270 Prostate cancer treatment28656,847
3271 Prostate disorders treatment39410,2
3272 Prostatic (benign) hyperplasia treatment18743,346
3273 Protease (Human cytomegalovirus) inhibitor1490,06
3274 Protease 3C (Human rhinovirus) inhibitor1770,668
3275 Protease activated receptor 1 antagonist1450,976
3276 Protease activated receptor antagonist1612,077
3277 Protease inhibitor5134,937
3278 Proteasome ATPase inhibitor39,732
3279 Proteasome endopeptidase complex inhibitor323,377
3280 Proteasome inhibitor1333,651
3281 Protein 30S ribosomal subunit inhibitor632,616
3282 Protein 50S ribosomal subunit inhibitor1081,216
3283 Protein C (activated) inhibitor140,874
3284 Protein glycation inhibitor40
3285 Protein kinase (CaMK, MLCK, PhK, SNF, KIN, NIM1, MAPKAP, POLO, CHK, ULK, RSK-2nd domain) inhibitor5671,071
3286 Protein kinase (CK1) delta inhibitor453,571
3287 Protein kinase (CK1) epsilon inhibitor214,668
3288 Protein kinase (CK1) inhibitor606,338
3289 Protein kinase (CK2) inhibitor973,84
3290 Protein kinase (Mos, Mil/Raf, MEKK, RIPK, TESK, LIMK, IRAK, ILK, Activin/TGF-beta) inhibitor6901,631
3291 Protein kinase (PKA, PKC, AKT, GRK, AGC-related, RSK, DBF2, SGK) inhibitor923,326
3292 Protein kinase A inhibitor4381,409
3293 Protein kinase B alpha inhibitor425,137
3294 Protein kinase B beta inhibitor2581,539
3295 Protein kinase B gamma inhibitor1203,15
3296 Protein kinase B inhibitor7212,519
3297 Protein kinase B stimulant274,899
3298 Protein kinase C alpha inhibitor6021,207
3299 Protein kinase C beta I inhibitor680,071
3300 Protein kinase C beta II inhibitor850,027
3301 Protein kinase C beta inhibitor4631,763
3302 Protein kinase C delta inhibitor5601,153
3303 Protein kinase C epsilon inhibitor3971,586
3304 Protein kinase C eta inhibitor3461,796
3305 Protein kinase C gamma inhibitor3721,062
3306 Protein kinase C inhibitor13552,744
3307 Protein kinase C mu inhibitor1441,442
3308 Protein kinase C nu inhibitor1351,639
3309 Protein kinase C stimulant611,175
3310 Protein kinase C theta inhibitor3791,252
3311 Protein kinase C zeta inhibitor1770,649
3312 Protein kinase inhibitor149726,275
3313 Protein kinase stimulant1015,504
3314 Protein N-acetylglucosaminyltransferase inhibitor80,484
3315 Protein phosphatase 2A inhibitor500,133
3316 Protein phosphatase inhibitor19713,577
3317 Protein synthesis inhibitor3565,778
3318 Protein synthesis stimulant93,733
3319 Protein-arginine deiminase inhibitor77,228
3320 Protein-arginine N-methyltransferase inhibitor60,004
3321 Protein-disulfide reductase (glutathione) inhibitor1119,786
3322 Protein-glucosylgalactosylhydroxylysine glucosidase inhibitor30,816
3323 Protein-glutamate methylesterase inhibitor133,824
3324 Protein-glutamate O-methyltransferase inhibitor41,122
3325 Protein-L-isoaspartate (D-aspartate) O-methyltransferase inhibitor30,019
3326 Protein-Npi-phosphohistidine-sugar phosphotransferase inhibitor124,005
3327 Protein-serine-threonine kinase inhibitor24003,902
3328 Protein-S-isoprenylcysteine O-methyltransferase inhibitor262,935
3329 Protein-synthesizing GTPase inhibitor159,952
3330 Protein-tyrosine kinase (PTK, not ETK, WZC) inhibitor6073,046
3331 Protein-tyrosine kinase Lyn inhibitor2044,024
3332 Protein-tyrosine kinase p55(blk) inhibitor337,55
3333 Protein-tyrosine phosphatase 1B inhibitor11851,768
3334 Protein-tyrosine phosphatase 2C inhibitor592,992
3335 Protein-tyrosine phosphatase beta inhibitor110,165
3336 Protein-tyrosine phosphatase C inhibitor40
3337 Protein-tyrosine phosphatase epsilon inhibitor50,002
3338 Protein-tyrosine phosphatase inhibitor18133,128
3339 Protein-tyrosine phosphatase mu inhibitor40,016
3340 Protein-tyrosine phosphatase yopH inhibitor90,918
3341 Protein-tyrosine sulfotransferase inhibitor102,113
3342 Protocatechuate 3,4-dioxygenase inhibitor280,67
3343 Protocatechuate 4,5-dioxygenase inhibitor110,05
3344 Protocollagen prolyl hydroxylase inhibitor1051,63
3345 Proto-oncogene tyrosine-protein kinase c-hck inhibitor2570,551
3346 Proto-oncogene tyrosine-protein kinase Fgr inhibitor149,529
3347 Proto-oncogene tyrosine-protein kinase Fyn inhibitor846,16
3348 Proto-oncogene tyrosine-protein kinase Kit inhibitor3862,184
3349 Proto-oncogene tyrosine-protein kinase Yes inhibitor427,09
3350 Prunasin beta-glucosidase inhibitor62,706
3351 Pseudolysin inhibitor419,112
3352 Pseudoporphyria716,069
3353 Pseudouridylate synthase inhibitor42,374
3354 Psychomotor impairment3417,682
3355 Psychoses6218,634
3356 Psychosexual dysfunction treatment615,557
3357 Pteridine reductase inhibitor92,127
3358 Pterin deaminase inhibitor46,856
3359 Pullulanase inhibitor74,965
3360 Pulmonary edema9413,951
3361 Pulmonary hypertension treatment13310,639
3362 Pure red cell aplasia910,811
3363 Purine antagonist210,132
3364 Purine biosynthesis inhibitor140,653
3365 Purine nucleosidase inhibitor260,329
3366 Purine nucleoside phosphorylase inhibitor2320,31
3367 Purinergic P2 agonist172,316
3368 Purinergic P2 antagonist8641,966
3369 Purinergic P2T antagonist741,907
3370 Purinergic P2X agonist60,063
3371 Purinergic P2X antagonist5251,328
3372 Purinergic P2X1 antagonist156,088
3373 Purinergic P2X2 antagonist411,092
3374 Purinergic P2X3 antagonist532,384
3375 Purinergic P2X4 antagonist140,196
3376 Purinergic P2X7 antagonist4520,546
3377 Purinergic P2Y agonist74,839
3378 Purinergic P2Y antagonist2741,799
3379 Purinergic P2Y1 antagonist752,694
3380 Purinergic P2Y12 antagonist1781,454
3381 Purinergic receptor agonist172,316
3382 Purinergic receptor antagonist9062,277
3383 Puromycin-sensitive aminopeptidase inhibitor40
3384 Putrescine carbamoyltransferase inhibitor60,124
3385 Putrescine oxidase inhibitor141,47
3386 Pyridoxal 4-dehydrogenase inhibitor90,024
3387 Pyridoxal kinase inhibitor453,634
3388 Pyridoxamine-oxaloacetate transaminase inhibitor130,157
3389 Pyridoxamine-phosphate oxidase inhibitor90,315
3390 Pyridoxamine-pyruvate transaminase inhibitor40,03
3391 Pyridoxine 4-oxidase inhibitor32,103
3392 Pyridoxine 5-dehydrogenase inhibitor60,788
3393 Pyrimidine antagonist411,727
3394 Pyrimidine-deoxynucleoside 2'-dioxygenase inhibitor60,892
3395 Pyroglutamyl-peptidase I inhibitor404,627
3396 Pyroglutamyl-peptidase II inhibitor1413,974
3397 Pyrroline-5-carboxylate reductase inhibitor170,98
3398 Pyruvate carboxylase inhibitor276,42
3399 Pyruvate decarboxylase inhibitor76,747
3400 Pyruvate dehydrogenase (cytochrome) inhibitor41,151
3401 Pyruvate dehydrogenase (lipoamide) inhibitor222,239
3402 Pyruvate dehydrogenase inhibitor254,713
3403 Pyruvate dehydrogenase kinase inhibitor1922,779
3404 Pyruvate dehydrogenase stimulant480,143
3405 Pyruvate kinase inhibitor382,748
3406 Pyruvate synthase inhibitor50,059
3407 Pyruvate, phosphate dikinase inhibitor210,778
3408 Pyruvate, water dikinase inhibitor100,543
3409 QT interval prolongation11713,831
3410 Quercetin 2,3-dioxygenase inhibitor111,709
3411 Queuine tRNA-ribosyltransferase inhibitor370,39
3412 Quinate 5-dehydrogenase inhibitor40,056
3413 Quinoline-4-carboxylate 2-oxidoreductase inhibitor42,148
3414 Quinoprotein glucose dehydrogenase inhibitor42,739
3415 Quisqualate antagonist44,435
3416 Radical formation agonist284,031
3417 Radioprotector24610,496
3418 Radiosensitizer18314,83
3419 Raf kinase B inhibitor2801,085
3420 Raf kinase C inhibitor932,295
3421 Raf kinase inhibitor6651,609
3422 RAS guanyl releasing protein antagonist40,001
3423 Raynaud's phenomenon treatment1112,872
3424 Reductant628,867
3425 Reductase inhibitor49,43
3426 RELA expression inhibitor1414,41
3427 Releasing hormone agonist235,584
3428 Renal disease treatment10016,173
3429 Renal failure treatment4895,316
3430 Renal tissue kallikrein inhibitor148,591
3431 Renilla-luciferin 2-monooxygenase inhibitor121,091
3432 Renin inhibitor16090,694
3433 Replication protein E1 (HPV) antagonist30
3434 Reproductive dysfunction21920,754
3435 Respiratory analeptic17512,037
3436 Respiratory distress syndrome treatment3219,034
3437 Respiratory failure32316,644
3438 Respiratory impairment3519,27
3439 Restenosis treatment7845,959
3440 Restless leg syndrome treatment215,477
3441 RET inhibitor816,647
3442 Retinal dehydrogenase inhibitor79,531
3443 Retinoic acid alpha receptor agonist270,275
3444 Retinoic acid alpha receptor antagonist2430,121
3445 Retinoic acid beta receptor agonist150,747
3446 Retinoic acid beta receptor antagonist2490,052
3447 Retinoic acid metabolism inhibitor88,611
3448 Retinoic acid receptor agonist1470,562
3449 Retinoic acid receptor antagonist3830,249
3450 Retinoic acid receptor gamma antagonist2780,341
3451 Retinoid X alpha receptor agonist230,478
3452 Retinoid X alpha receptor antagonist2120,016
3453 Retinoid X beta receptor antagonist580,043
3454 Retinoid X gamma receptor antagonist630,03
3455 Retinoid X receptor agonist1100,199
3456 Retinoid X receptor antagonist2210,019
3457 Retinol dehydrogenase inhibitor63,381
3458 Retinol O-fatty-acyltransferase inhibitor70,557
3459 Retinopathy treatment227,919
3460 Retinoprotector2117,701
3461 Retinyl-palmitate esterase inhibitor181,841
3462 Retroperitoneal fibrosis918,987
3463 Reverse transcriptase (Hepatitis B) inhibitor360
3464 Rhamnulose-1-phosphate aldolase inhibitor72,432
3465 Rheumatoid arthritis treatment16779,257
3466 Rhinitis treatment28413,67
3467 Rhizopuspepsin inhibitor45,972
3468 Rho-associated kinase I inhibitor762,197
3469 Rho-associated kinase II inhibitor2301,035
3470 Rho-associated kinase inhibitor3411,029
3471 Rhodesain inhibitor780,326
3472 Rhodopsin kinase inhibitor345,9
3473 Rhodotorulapepsin inhibitor93,233
3474 Ribitol 2-dehydrogenase inhibitor60,475
3475 Riboflavin kinase inhibitor240,263
3476 Riboflavin phosphotransferase inhibitor41,066
3477 Riboflavin synthase inhibitor120,118
3478 Ribonuclease inhibitor485,06
3479 Ribonuclease L inhibitor90
3480 Ribonuclease T2 inhibitor260,108
3481 Ribonuclease U2 inhibitor51,058
3482 Ribonucleoside diphosphate reductase inhibitor931,857
3483 Ribonucleoside triphosphate reductase inhibitor1710,15
3484 Ribonucleotide reductase inhibitor1991,397
3485 Ribose-5-phosphate adenylyltransferase inhibitor70,882
3486 Ribose-5-phosphate isomerase inhibitor210,809
3487 Ribose-5-phosphate-ammonia ligase inhibitor71,292
3488 Ribose-phosphate diphosphokinase inhibitor380,667
3489 Ribosomal protein S6 kinase 1, 70-kDa inhibitor643,668
3490 Ribosomal protein S6 kinase inhibitor1212,934
3491 Ribosomal protein S6 kinase, 70-kDa inhibitor984,32
3492 Ribosomal protein S6 kinase, 90kD, polypeptide 5 inhibitor40,001
3493 Ribosomal protein S6 kinase, 90-kDa inhibitor423,756
3494 Ribosylpyrimidine nucleosidase inhibitor90,192
3495 Ribulose-bisphosphate carboxylase inhibitor151,31
3496 Ribulose-phosphate 3-epimerase inhibitor313,94
3497 RNA agonist30,072
3498 RNA directed DNA polymerase inhibitor1299,113
3499 RNA ligase (ATP) inhibitor150,014
3500 RNA synthesis inhibitor10610,209
3501 RNA-directed RNA polymerase (Influenza A) inhibitor130,023
3502 RNA-directed RNA polymerase inhibitor2613,862
3503 RNA-directed RNA polymerase stimulant70,164
3504 Rotamase (FKBP) inhibitor60,321
3505 Rotamase (FKBP12) inhibitor770,683
3506 rRNA (adenosine-2'-O-)-methyltransferase inhibitor120,148
3507 Rubefacient72,972
3508 Rubredoxin-NAD+ reductase inhibitor1418,028
3509 Ryanodine receptor 1 antagonist70,66
3510 Ryanodine receptor antagonist70,66
3511 Saccharolysin inhibitor41,349
3512 Saccharopepsin inhibitor312,297
3513 Saccharopine dehydrogenase (NAD+, L-glutamate-forming) inhibitor40,698
3514 Saccharopine dehydrogenase (NAD+, L-lysine-forming) inhibitor192,1
3515 Saccharopine dehydrogenase (NADP+, L-glutamate-forming) inhibitor50,953
3516 Saccharopine dehydrogenase (NADP+, L-lysine-forming) inhibitor120,519
3517 S-adenosyl-L-homocysteine hydrolase inhibitor690,033
3518 S-adenosyl-L-methionine decarboxylase inhibitor580,149
3519 Salicylate 1-monooxygenase inhibitor63,396
3520 S-alkylcysteine lyase inhibitor32,561
3521 Saluretic957,199
3522 Saponin-like80,002
3523 Sarcopenia treatment252,14
3524 Sarcosine oxidase inhibitor141,503
3525 Sclerosant45,761
3526 Scyllo-inosamine-4-phosphate amidinotransferase inhibitor40,614
3527 Scytalone dehydratase inhibitor210,846
3528 Secretase alpha stimulant1115,205
3529 Secretase beta 1 inhibitor7540,941
3530 Secretase beta 2 inhibitor2960,35
3531 Secretase beta inhibitor9561,023
3532 Secretase gamma inhibitor4150,192
3533 Secretase inhibitor13671,25
3534 Secretase stimulant1115,205
3535 Secretory phospholipase A2 inhibitor1511,12
3536 Sedative12238,241
3537 Sedoheptulose-bisphosphatase inhibitor74,554
3538 Selectin antagonist2191,46
3539 Selectin E antagonist1471,834
3540 Selectin L antagonist300,071
3541 Selectin P antagonist650,164
3542 Selenide, water dikinase inhibitor40,016
3543 Selenocysteine lyase inhibitor31,047
3544 Sensitization1617,499
3545 Sensory disturbance80018,227
3546 Sepiapterin deaminase inhibitor120,306
3547 Sepiapterin reductase inhibitor464,272
3548 Sepsis treatment1546,609
3549 Septic shock treatment9227,886
3550 Serine 3-dehydrogenase inhibitor61,086
3551 Serine carboxypeptidase inhibitor381,999
3552 Serine O-acetyltransferase inhibitor154,072
3553 Serine protease unspecified inhibitor225,815
3554 Serine-glyoxylate transaminase inhibitor120,621
3555 Serine-phosphoethanolamine synthase inhibitor101,314
3556 Serine-pyruvate transaminase inhibitor41,669
3557 Serine-sulfate ammonia-lyase inhibitor300,449
3558 Serine-tRNA ligase inhibitor60,947
3559 Serine-type D-Ala-D-Ala carboxypeptidase inhibitor360,464
3560 Serralysin inhibitor223,711
3561 Serratia marcescens nuclease inhibitor72,918
3562 Serum-glucocorticoid regulated kinase 1 inhibitor2412,453
3563 Serum-glucocorticoid regulated kinase inhibitor526,671
3564 Severe acute respiratory syndrome treatment297,296
3565 S-formylglutathione hydrolase inhibitor811,296
3566 Shab potassium channel blocker414,804
3567 Shaker potassium channel blocker8241,568
3568 Shal potassium channel blocker822,146
3569 Shikimate 5-dehydrogenase inhibitor61,596
3570 Shikimate kinase inhibitor222,816
3571 Shikimate O-hydroxycinnamoyltransferase inhibitor42,485
3572 Shivering616,381
3573 Shock treatment552,479
3574 Sialorrhea2216,522
3575 Sickle-cell anemia treatment547,644
3576 Sigma 1 receptor agonist143,44
3577 Sigma 1 receptor antagonist10580,514
3578 Sigma 2 receptor antagonist5850,424
3579 Sigma 3 receptor antagonist110,008
3580 Sigma receptor agonist236,788
3581 Sigma receptor antagonist21611,265
3582 Signal peptidase I inhibitor123,027
3583 Signal peptidase IB inhibitor30
3584 Signal transduction pathways inhibitor38997,86
3585 Simian immunodeficiency virus proteinase inhibitor413,676
3586 Sirtuin 2 inhibitor390,318
3587 Sirtuin inhibitor470,384
3588 Site-specific DNA-methyltransferase (adenine-specific) inhibitor40,913
3589 Skeletal muscle relaxant2198,197
3590 Skin irritation, corrasive159,276
3591 Skin irritation, high4054,441
3592 Skin irritation, inactive1886,424
3593 Skin irritation, moderate2692,437
3594 Skin irritation, weak4683,173
3595 Skin irritative effect11174,061
3596 Skin whitener482,522
3597 Sleep apnea treatment794,034
3598 Sleep disorders treatment12713,885
3599 Sleep disturbance118817,962
3600 Small monomeric GTPase inhibitor30,532
3601 S-methyl-5-thioadenosine phosphorylase inhibitor470,45
3602 S-methyl-5-thioribose kinase inhibitor90,87
3603 SMN2 expression enhancer227,919
3604 Smo receptor agonist30
3605 Smo receptor antagonist1220,653
3606 Smooth muscle myosin light chain kinase inhibitor469,978
3607 Snapalysin inhibitor41,273
3608 Sneezing5618,282
3609 Sodium channel (voltage-gated) blocker5373,529
3610 Sodium channel blocker10046,194
3611 Sodium channel blocker class Ib62,788
3612 Sodium/bile acid cotransporter inhibitor162,975
3613 Sodium/calcium exchanger 1 inhibitor252,728
3614 Sodium/calcium exchanger inhibitor1091,259
3615 Sodium/glucose cotransporter 1 inhibitor1800,803
3616 Sodium/glucose cotransporter 2 inhibitor4250,199
3617 Sodium/glucose cotransporter inhibitor5870,601
3618 Sodium/hydrogen exchanger 1 inhibitor2960,136
3619 Sodium/hydrogen exchanger 2 inhibitor1570,047
3620 Sodium/hydrogen exchanger 3 inhibitor2200,126
3621 Sodium/hydrogen exchanger 5 inhibitor60,442
3622 Sodium/hydrogen exchanger inhibitor6650,183
3623 Sodium-dependent vitamin C transporter 2 inhibitor30,004
3624 Somatostatin 1 antagonist2190,611
3625 Somatostatin 2 agonist71,249
3626 Somatostatin 2 antagonist3190,637
3627 Somatostatin 3 antagonist2760,569
3628 Somatostatin 4 antagonist3110,586
3629 Somatostatin 5 agonist150,086
3630 Somatostatin 5 antagonist2790,706
3631 Somatostatin agonist343,684
3632 Somatostatin antagonist3970,776
3633 Sorbitol-6-phosphate 2-dehydrogenase inhibitor32,341
3634 Sorbose dehydrogenase inhibitor30,519
3635 Spasmolytic14579,324
3636 Spasmolytic, Papaverin-like1886,704
3637 Spasmolytic, urinary2414,614
3638 Spermicide5413,646
3639 Spermidine dehydrogenase inhibitor518,029
3640 Spermidine synthase inhibitor360,478
3641 Spermine antagonist30,035
3642 Spermine synthase inhibitor230,473
3643 Sphinganine kinase inhibitor617,703
3644 Sphinganine-1-phosphate aldolase inhibitor62,058
3645 Sphingomyelinase inhibitor151,474
3646 Sphingosine 1-phosphate receptor 1 agonist1070,044
3647 Sphingosine 1-phosphate receptor 1 antagonist1227,011
3648 Sphingosine 1-phosphate receptor 3 agonist120,003
3649 Sphingosine 1-phosphate receptor 3 antagonist1571,564
3650 Sphingosine 1-phosphate receptor 4 agonist50,011
3651 Sphingosine 1-phosphate receptor 4 antagonist2085,275
3652 Sphingosine 1-phosphate receptor 5 agonist513,714
3653 Sphingosine 1-phosphate receptor 5 antagonist911,227
3654 Sphingosine 1-phosphate receptor agonist1080,041
3655 Sphingosine 1-phosphate receptor antagonist3445,187
3656 Sphingosine kinase 1 inhibitor230,124
3657 Sphingosine kinase inhibitor320,934
3658 Sphingosine kinase stimulant30
3659 Splenomegaly2717,087
3660 Sporulation kinase A inhibitor110,582
3661 Squalene epoxidase inhibitor713,958
3662 Squalene synthetase inhibitor5040,641
3663 Squalene-hopene cyclase inhibitor353,081
3664 Src kinase inhibitor26293,086
3665 Stearoyl-CoA desaturase inhibitor2991,833
3666 Stem cell growth factor agonist1902,844
3667 Steroid 17-alpha-hydroxylase/17,20 lyase inhibitor3650,512
3668 Steroid 9alpha-monooxygenase inhibitor30,213
3669 Steroid DELTA-isomerase inhibitor282,703
3670 Steroid N-acetylglucosaminyltransferase inhibitor44,296
3671 Steroid sulfotransferase inhibitor117,316
3672 Steroid synthesis inhibitor1013,12
3673 Steroid-like180,263
3674 Sterol 24-C-methyltransferase inhibitor271,486
3675 Sterol 3-beta-glucosyltransferase inhibitor124,268
3676 Stipitatonate decarboxylase inhibitor50,166
3677 Stomatitis25521,646
3678 Streptogrisin A inhibitor30,041
3679 Streptomycin 6-kinase inhibitor60,317
3680 Streptopain inhibitor131,314
3681 Stroke treatment48117,756
3682 Strombine dehydrogenase inhibitor50,04
3683 Stromelysin 2 inhibitor119,812
3684 Styrene-oxide isomerase inhibitor31,35
3685 Substance P antagonist3071,971
3686 Subtilisin inhibitor273,947
3687 Succinate dehydrogenase inhibitor144,275
3688 Succinate-CoA ligase (ADP-forming) inhibitor161,754
3689 Succinate-hydroxymethylglutarate CoA-transferase inhibitor80,756
3690 Succinate-semialdehyde dehydrogenase [NAD(P)+] inhibitor715,44
3691 Succinate-semialdehyde dehydrogenase inhibitor200,737
3692 Succinic dehydrogenase inhibitor83,194
3693 Sucrose alpha-glucosidase inhibitor190,404
3694 Sucrose phosphorylase inhibitor50,037
3695 Sucrose synthase inhibitor160,77
3696 Sucrose-phosphate phosphatase inhibitor70,199
3697 Sucrose-phosphate synthase inhibitor192,703
3698 Sugar-phosphatase inhibitor39,852
3699 Sulfate adenylyltransferase (ADP) inhibitor81,422
3700 Sulfate adenylyltransferase inhibitor141,69
3701 Sulfinoalanine decarboxylase inhibitor180,647
3702 Sulfite dehydrogenase inhibitor915,33
3703 Sulfite oxidase inhibitor96,232
3704 Sulfite reductase inhibitor62,968
3705 Sulfonylureas30,074
3706 Sulfotransferase substrate1833,765
3707 Sulfur dioxygenase inhibitor61,306
3708 Sulfur reductase inhibitor813,4
3709 SULT1A1 substrate422,173
3710 SULT1A2 substrate240,638
3711 SULT1A3 substrate172,234
3712 SULT1E1 substrate41,411
3713 SULT2A1 substrate95,852
3714 Superoxide dismutase inhibitor1511,566
3715 Sweating10719,023
3716 Sweetener244,407
3717 Syk tyrosine kinase inhibitor2682,463
3718 Synaptic vesicle protein SV2, levetiracetam binding site antagonist320,001
3719 Systemic lupus erythematosus treatment12413,142
3720 T cell inhibitor2474,673
3721 T cell receptor antagonist170,004
3722 T cell receptor gamma-delta antagonist170,004
3723 T2-induced deoxynucleotide kinase inhibitor30,013
3724 Tachycardiac43718,9
3725 Tagaturonate reductase inhibitor30,541
3726 Tankyrase 2 inhibitor50
3727 Tankyrase inhibitor1011,078
3728 Tannase inhibitor140,425
3729 Tardive dyskinesia treatment406,535
3730 Tartrate decarboxylase inhibitor50,025
3731 Tartrate dehydrogenase inhibitor50,004
3732 Taurine dehydrogenase inhibitor713,881
3733 Taurine-2-oxoglutarate transaminase inhibitor32,423
3734 Taurocyamine kinase inhibitor32,057
3735 Tauropine dehydrogenase inhibitor84,061
3736 T-cell protein-tyrosine phosphatase inhibitor2430,847
3737 TEC kinase inhibitor252,547
3738 Telangiectasia1810,447
3739 Telomerase inhibitor2063,872
3740 Telomerase stimulant60
3741 Tentoxilysin inhibitor45,465
3742 Teratogen15529,477
3743 Testosterone 17beta-dehydrogenase (NADP+) inhibitor313,516
3744 Testosterone 17beta-dehydrogenase inhibitor113,023
3745 Testosterone agonist50,356
3746 Tetanus neurotoxin inhibitor30
3747 Tetracycline antiport transporter antagonist360,001
3748 Tetrahydroxynaphthalene reductase inhibitor71,808
3749 TGF beta receptor type I kinase inhibitor1970,354
3750 TGF beta receptor type II kinase inhibitor140,004
3751 TH expression enhancer1111,486
3752 Theanine hydrolase inhibitor130,093
3753 Thermitase inhibitor129,779
3754 Thermolysin inhibitor230,343
3755 Thermomycolin inhibitor30,436
3756 Thiamine pyridinylase inhibitor514,064
3757 Thiamine-phosphate diphosphorylase inhibitor71,204
3758 Thiamine-phosphate kinase inhibitor51,378
3759 Thiamine-triphosphatase inhibitor912,289
3760 Thiazolidinedione180,047
3761 Thimet oligopeptidase inhibitor206,257
3762 Thioether S-methyltransferase inhibitor30,526
3763 Thiol oxidase inhibitor135,148
3764 Thiol protease inhibitor2327,208
3765 Thiol S-methyltransferase inhibitor81,911
3766 Thiol sulfotransferase inhibitor40,009
3767 Thiopurine S-methyltransferase inhibitor175,617
3768 Thioredoxin inhibitor38,098
3769 Thioredoxin reductase inhibitor537,008
3770 Thiosulfate dehydrogenase inhibitor1012,114
3771 Thiosulfate sulfurtransferase inhibitor211,219
3772 Threonine aldolase inhibitor52,413
3773 Threonine ammonia-lyase inhibitor271,518
3774 Threonine synthase inhibitor110,161
3775 Threonine-tRNA ligase inhibitor56,812
3776 Thrombin inhibitor24822,013
3777 Thrombocytopenia49418,373
3778 Thrombocytopoiesis inhibitor1116,011
3779 Thrombolytic1436,963
3780 Thrombophlebitis14619,845
3781 Thrombopoietin agonist1130,03
3782 Thromboxane A2 antagonist2801,74
3783 Thromboxane agonist30,048
3784 Thromboxane antagonist4912,475
3785 Thromboxane B2 antagonist1815,838
3786 Thromboxane synthase inhibitor9001,362
3787 Thromboxane synthase stimulant31,099
3788 Thymidine kinase (Herpes simplex virus 1) inhibitor380,01
3789 Thymidine kinase (Herpes simplex virus 2) inhibitor150,003
3790 Thymidine kinase 1 inhibitor281,983
3791 Thymidine kinase 2 inhibitor250,01
3792 Thymidine kinase inhibitor1921,734
3793 Thymidine phosphorylase inhibitor650,605
3794 Thymidine-triphosphatase inhibitor60,108
3795 Thymidylate 5'-phosphatase inhibitor519,234
3796 Thymidylate synthase inhibitor8390,679
3797 Thymine dioxygenase inhibitor140,018
3798 Thyroid hormone agonist1041,379
3799 Thyroid hormone alpha 1 agonist50,004
3800 Thyroid hormone alpha 1 antagonist120,003
3801 Thyroid hormone alpha agonist50,004
3802 Thyroid hormone alpha antagonist930,023
3803 Thyroid hormone antagonist2610,695
3804 Thyroid hormone beta 1 agonist50,004
3805 Thyroid hormone beta 1 antagonist1560,038
3806 Thyroid hormone beta agonist740,031
3807 Thyroid hormone beta antagonist1780,038
3808 Thyrotropin releasing hormone agonist150,005
3809 Thyrotropin releasing hormone antagonist60,001
3810 Thyroxine 5-deiodinase inhibitor75,376
3811 TIE antagonist7491,583
3812 TIE-2 agonist60
3813 TIE-2 antagonist7341,582
3814 TNF convertase inhibitor10280,191
3815 TNF expression inhibitor5512,415
3816 Tocolytic1412,206
3817 Toll-Like receptor 2 antagonist100,023
3818 Toll-Like receptor 7 agonist860,214
3819 Toll-Like receptor 8 agonist90,003
3820 Toll-Like receptor agonist880,691
3821 Toll-Like receptor antagonist1612,673
3822 Topoisomerase I inhibitor4783,75
3823 Topoisomerase II inhibitor7263,498
3824 Torsades de pointes9017,764
3825 Torticollis2816,499
3826 Toxic511213,559
3827 Toxic, gastrointestinal136218,128
3828 Toxic, respiration8017,894
3829 Toxic, respiratory center157,302
3830 Toxic, vascular19416,509
3831 TP53 expression enhancer9917,725
3832 Tpr proteinase (Porphyromonas gingivalis) inhibitor414,67
3833 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase inhibitor424,183
3834 Trans-2-enoyl-CoA reductase (NAD+) inhibitor41,151
3835 Trans-acenaphthene-1,2-diol dehydrogenase inhibitor519,151
3836 Transactivator transcription protein inhibitor2514,945
3837 Transaldolase inhibitor50,02
3838 Transcortin receptor antagonist290,032
3839 Transcription factor AP-1 inhibitor2492,894
3840 Transcription factor inhibitor12878,337
3841 Transcription factor NF kappa A inhibitor715,943
3842 Transcription factor NF kappa B inhibitor5344,397
3843 Transcription factor NF kappa B stimulant714,704
3844 Transcription factor rho inhibitor70
3845 Transcription factor STAT inhibitor26910,031
3846 Transcription factor STAT3 inhibitor2348,96
3847 Transcription factor STAT6 inhibitor201,506
3848 Transcription factor stimulant714,704
3849 Transforming growth factor antagonist2411,415
3850 Transforming growth factor beta 1 agonist311,05
3851 Transforming growth factor beta 1 antagonist1860,798
3852 Transforming growth factor beta 3 antagonist200,01
3853 Transforming growth factor beta antagonist2271,049
3854 Transglutaminase 2 inhibitor272,697
3855 Transketolase inhibitor78,318
3856 Translation initiation factor IF-2 antagonist50,021
3857 Trans-octaprenyltranstransferase inhibitor120,835
3858 Trans-pentaprenyltranstransferase inhibitor51,223
3859 Transplant rejection treatment6948,655
3860 Transthyretin amyloid fibril formation inhibitor291,576
3861 Trehalose-phosphatase inhibitor30,444
3862 Tremor53716,51
3863 Triacetate-lactonase inhibitor31,059
3864 Trimerelysin II inhibitor70,79
3865 Trimethylamine dehydrogenase inhibitor96,774
3866 Trimethylamine-N-oxide reductase inhibitor110,978
3867 Trimethylamine-oxide aldolase inhibitor519,014
3868 Trimethyllysine dioxygenase inhibitor71,81
3869 Triose-phosphate isomerase inhibitor231,45
3870 Tripeptide aminopeptidase inhibitor235,956
3871 Tripeptidyl peptidase II inhibitor360,071
3872 Tripeptidyl-peptidase I inhibitor223,66
3873 TRKA antagonist1461,741
3874 TRKB antagonist214,521
3875 tRNA (adenine-N1-)-methyltransferase inhibitor60,077
3876 tRNA (cytosine-5-)-methyltransferase inhibitor51,477
3877 tRNA (guanine-N1-)-methyltransferase inhibitor40,651
3878 tRNA (guanine-N2-)-methyltransferase inhibitor50,63
3879 tRNA (guanine-N7-)-methyltransferase inhibitor60,907
3880 tRNA (uracil-5-)-methyltransferase inhibitor100,064
3881 tRNA adenylyltransferase inhibitor91,37
3882 tRNA cytidylyltransferase inhibitor151,057
3883 tRNA methyltransferase inhibitor220,5
3884 tRNA nucleotidyltransferase inhibitor30,816
3885 tRNA-pseudouridine synthase I inhibitor33,161
3886 Tropinesterase inhibitor314,316
3887 TRPA1 agonist106,662
3888 TRPA1 antagonist172,222
3889 Trypanothione-disulfide reductase inhibitor623,902
3890 Trypsin inhibitor14011,109
3891 Tryptase 1 inhibitor1440,052
3892 Tryptase inhibitor1981,401
3893 Tryptophan 2,3-dioxygenase inhibitor2411,914
3894 Tryptophan 2-monooxygenase inhibitor203,803
3895 Tryptophan 5 hydroxylase inhibitor255,167
3896 Tryptophan alpha,beta-oxidase inhibitor44,174
3897 Tryptophan dimethylallyltransferase inhibitor82,67
3898 Tryptophan hydroxylase 1 inhibitor160,01
3899 Tryptophan synthase inhibitor140,465
3900 Tryptophan transaminase inhibitor41,227
3901 Tryptophanamidase inhibitor51,493
3902 Tryptophan-tRNA ligase inhibitor381,024
3903 Tryptophanyl aminopeptidase inhibitor30,986
3904 TTK protein kinase inhibitor63,69
3905 Tubulin agonist260,014
3906 Tubulin antagonist11642,751
3907 Tubulin GTPase inhibitor60,329
3908 Tubulin-tyrosine ligase inhibitor171,291
3909 Tubulinyl-Tyr carboxypeptidase inhibitor60,169
3910 Tumour necrosis factor alpha antagonist6885,297
3911 Tumour necrosis factor alpha release inhibitor24225,551
3912 Tumour necrosis factor antagonist7816,279
3913 Twitching718,814
3914 Tyrosine 2,3-aminomutase inhibitor60,556
3915 Tyrosine 3 hydroxylase inhibitor1211,636
3916 Tyrosine 3 hydroxylase stimulant30,004
3917 Tyrosine kinase inhibitor60595,093
3918 Tyrosine kinase stimulant34,411
3919 Tyrosine phenol-lyase inhibitor200,188
3920 Tyrosine transaminase inhibitor341,449
3921 Tyrosine-ester sulfotransferase inhibitor241,269
3922 Tyrosine-protein kinase EMT inhibitor1991,056
3923 Tyrosine-protein kinase receptor antagonist1611,689
3924 Tyrosine-protein kinase receptor FLT3 inhibitor3881,794
3925 Tyrosine-protein kinase TYRO 10 inhibitor87,95
3926 Ubiquinol-cytochrome-c reductase inhibitor1018,357
3927 Ubiquitin thiolesterase inhibitor74,037
3928 Ubiquitin-protein ligase inhibitor272,899
3929 UDP-3-O-acyl-N-acetylglucosamine deacetylase inhibitor600,101
3930 UDP-glucose 4-epimerase inhibitor282,786
3931 UDP-glucose 6-dehydrogenase inhibitor84,912
3932 UDP-glucose-hexose-1-phosphate uridylyltransferase inhibitor182,446
3933 UDP-glucuronate 4-epimerase inhibitor130,018
3934 UDP-glucuronate 5'-epimerase inhibitor30,03
3935 UDP-glucuronate decarboxylase inhibitor120,456
3936 UDP-glucuronosyltransferase substrate8176,966
3937 UDP-N-acetylglucosamine 1-carboxyvinyltransferase inhibitor200,999
3938 UDP-N-acetylglucosamine 2-epimerase inhibitor70,847
3939 UDP-N-acetylglucosamine 4-epimerase inhibitor39,85
3940 UDP-N-acetylglucosamine diphosphorylase inhibitor80,692
3941 UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase inhibitor111,922
3942 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase inhibitor90,344
3943 UDP-N-acetylmuramate dehydrogenase inhibitor201,204
3944 UDP-N-acetylmuramate-L-alanine ligase inhibitor182,397
3945 UDP-N-acetylmuramoylalanine-D-glutamate ligase inhibitor181,232
3946 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase inhibitor80,035
3947 UDP-sugar diphosphatase inhibitor40,444
3948 UGT1A substrate3136,949
3949 UGT1A1 substrate1135,573
3950 UGT1A10 substrate995,433
3951 UGT1A3 substrate1185,74
3952 UGT1A4 substrate1285,486
3953 UGT1A5 substrate165,874
3954 UGT1A6 substrate857,087
3955 UGT1A7 substrate615,572
3956 UGT1A8 substrate994,574
3957 UGT1A9 substrate9210,712
3958 UGT2B substrate2594,63
3959 UGT2B1 substrate993,905
3960 UGT2B10 substrate209,076
3961 UGT2B11 substrate374,475
3962 UGT2B12 substrate413,217
3963 UGT2B15 substrate844,514
3964 UGT2B17 substrate157,309
3965 UGT2B18 substrate63,019
3966 UGT2B19 substrate50,793
3967 UGT2B20 substrate190,418
3968 UGT2B23 substrate50,793
3969 UGT2B28 substrate83,8
3970 UGT2B30 substrate50,793
3971 UGT2B4 substrate358,997
3972 UGT2B4D substrate50,793
3973 UGT2B4E substrate50,793
3974 UGT2B7 substrate1384,798
3975 UGT2B7H substrate282,071
3976 UGT2B7Y substrate282,071
3977 UGT2B9 substrate394,925
3978 Ulcer, aphthous916,892
3979 Ulcer, gastric279,281
3980 Ulcer, peptic3411,524
3981 Ulceration539,264
3982 Ulcerative colitis treatment30,013
3983 Undecaprenyl-diphosphatase inhibitor51,719
3984 Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase inhibitor34,405
3985 Undecaprenyl-phosphate galactose phosphotransferase inhibitor60,034
3986 Undecaprenyl-phosphate mannosyltransferase inhibitor35,199
3987 Uracil phosphoribosyltransferase inhibitor140,447
3988 Urate transporter 1 inhibitor292,1
3989 Urate-ribonucleotide phosphorylase inhibitor127,678
3990 Urease inhibitor187,503
3991 Urethanase inhibitor1012,556
3992 Uric acid excretion stimulant1225,685
3993 Uridine kinase inhibitor70,692
3994 Uridine nucleosidase inhibitor150,867
3995 Uridine phosphorylase inhibitor1060,207
3996 Urinary incontinence treatment19594,612
3997 Urinary retention18119,603
3998 Urine discoloration94,615
3999 Urocanate hydratase inhibitor160,599
4000 Urokinase inhibitor3040,943
4001 Urolithiasis treatment69,987
4002 Urologic disorders treatment20255,668
4003 Uroporphyrinogen decarboxylase inhibitor300,922
4004 Uroporphyrinogen-III synthase inhibitor96,027
4005 Urotensin II agonist260,008
4006 Urotensin II antagonist450,326
4007 Urticaria treatment84,621
4008 Uterine relaxant4313,889
4009 Uterine rupture30,022
4010 Uterine stimulant335,255
4011 UTP-glucose-1-phosphate uridylyltransferase inhibitor100,024
4012 Valine decarboxylase inhibitor40,968
4013 Valine dehydrogenase (NADP+) inhibitor60,51
4014 Valine-pyruvate transaminase inhibitor30,005
4015 Valine-tRNA ligase inhibitor102,159
4016 Vanilloid 1 agonist1413,71
4017 Vanilloid 1 antagonist2480,683
4018 Vanilloid 3 antagonist60
4019 Vanilloid 4 agonist60,003
4020 Vanilloid 4 antagonist732,071
4021 Vanilloid agonist207,891
4022 Vanilloid antagonist10660,751
4023 Vanillyl-alcohol oxidase inhibitor70,494
4024 Vascular (periferal) disease treatment7998,865
4025 Vascular adhesion protein 1 inhibitor119,877
4026 Vascular dementia treatment1011,613
4027 Vascular endothelial growth factor 1 antagonist5932,658
4028 Vascular endothelial growth factor 2 antagonist32192,07
4029 Vascular endothelial growth factor 3 antagonist3612,4
4030 Vascular endothelial growth factor antagonist39132,91
4031 Vasculitis treatment264,711
4032 Vasodilator110510,716
4033 Vasodilator, coronary22014,161
4034 Vasodilator, peripheral19014,807
4035 Vasopressin 1 agonist170,003
4036 Vasopressin 1 antagonist9510,45
4037 Vasopressin 1A agonist90
4038 Vasopressin 1A antagonist8470,321
4039 Vasopressin 1B agonist80,001
4040 Vasopressin 1B antagonist2920,244
4041 Vasopressin 2 agonist1320,139
4042 Vasopressin 2 antagonist7480,245
4043 Vasopressor12413,256
4044 Vasoprotector2218,927
4045 VCAM antagonist4141,058
4046 VCAM-1 antagonist4131,059
4047 VCAM1 expression inhibitor564,977
4048 VEGF expression inhibitor385,862
4049 VEGFR2 expression inhibitor50
4050 Venom exonuclease inhibitor812,803
4051 Venombin A inhibitor91,711
4052 Venombin AB inhibitor511,82
4053 Vesicant60,627
4054 Vesicle monoamine transporter 2 inhibitor130,002
4055 Vesicle monoamine transporter inhibitor140,446
4056 Vesicular acetylcholine transporter inhibitor750,162
4057 Vesicular glutamate transport inhibitor40
4058 Vestibular dysfunction107,979
4059 Vibriolysin inhibitor120,135
4060 Viral entry inhibitor6613,355
4061 Viral fusion inhibitor30
4062 Visual acuity impairment610,796
4063 Vitamin1021,827
4064 Vitamin D receptor agonist1020,044
4065 Vitamin D receptor antagonist750,023
4066 Vitamin D3 hydroxylase inhibitor150,081
4067 Vitamin D-like160,052
4068 Vitamin K-like190,048
4069 Vitamin-K-epoxide reductase (warfarin-insensitive) inhibitor75,289
4070 Vitronectin receptor antagonist17210,317
4071 VLA-4 antagonist11190,423
4072 Vomilenine glucosyltransferase inhibitor61,67
4073 Weakness25019,46
4074 Wee-1 tyrosine kinase inhibitor50,153
4075 Weight gain2514,537
4076 Weight loss16917,041
4077 Withdrawal1317,198
4078 Wound healing agent2829,324
4079 Xaa-Pro dipeptidyl-peptidase inhibitor111,626
4080 Xanthine dehydrogenase inhibitor932,017
4081 Xanthine oxidase inhibitor1104,24
4082 Xanthine oxidase substrate422,354
4083 Xanthine phosphoribosyltransferase inhibitor390,291
4084 Xanthine-like230,139
4085 Xanthommatin reductase inhibitor51,471
4086 Xenobiotic-transporting ATPase inhibitor138,09
4087 Xerostomia40519,991
4088 X-His dipeptidase inhibitor222,355
4089 X-methyl-His dipeptidase inhibitor1012,18
4090 X-Pro dipeptidase inhibitor211,449
4091 X-Trp aminopeptidase inhibitor70,557
4092 Xylan 1,4-beta-xylosidase inhibitor140,649
4093 Xylan endo-1,3-beta-xylosidase inhibitor52,836
4094 Xylose isomerase inhibitor111,283
4095 YAK3 inhibitor150,007
4096 Yawning3913,389
4097 Yeast ribonuclease inhibitor33,836
4098 ZAP-70 protein tyrosine kinase inhibitor1041,77
4099 Zinc deficiency42,527